Biophysical Society 59th Annual Meeting Program Guide

1362-P os B oard B313 MALIGNANT HYPERTHERMIA SUSCEPTIBILITY MUTATION CAV1.1 R174W DRAMATICALLY ALTERS RYR1 SINGLE CHANNEL FUNCTION. Wei Feng , Yao Dong, Roger Bannister, Philip Hopkins, Clara Franzini-Armstrong, Kurt Beam, Paul D. Allen, Isaac Pessah 1363-P os B oard B314 EFFECTS OF MH AND CCD MUTATIONS IN THE CENTRAL REGION ON RYR1 CHANNELS. Takashi Murayama , Nagomi Kurebayashi, Toshiko Yamazawa, Hideto Oyamada, Junji Suzuki, Kazunori Kanemaru, Katsuji Oguchi, Masamitsu Iino, Takashi Sakurai 1364-P os B oard B315 CHARACTERIZATION OF DUAL MUTANT RYR1D-S100A1KO MICE WITH DISRUPTED CAM AND S100A1 BINDING TO CAMBD2 AND LACKING S100A1 EXPRESSION. Erick O. Hernández-Ochoa , Camilo Vanegas, Stephen J.P. Pratt, Richard M. Lovering, Martin F. Schneider 1365-P os B oard B316 CORRELATION BETWEEN FKBP12/12.6 BOUND TO RYRS, CHANNEL OPENING TO MAXIMAL OR SUBMAXIMAL CONDUCTANCE LEVELS AND MYOPATHY. Gregory Steele, Philip G. Board, Nicole A. Beard, Angela F. Dulhunty Cardiac, Smooth, and Skeletal Muscle Electrophysiology II (Boards B317-B332) 1366-P os B oard B317 A COMPARISON OF ACUTELY ISOLATED HUMAN VENTRICULAR MYOCYTES WITH STEM CELL DERIVED CARDIOCYTES. Aaron D. Kaplan, Agnieszka Lis, Carlos Li, Lei Yang, Michael J. Morales, Glenna C.L. Bett, Randall L. Rasmusson 1367-P os B oard B318 AGING ALTERS CAMP SIGNALING AND MEMBRANE- DELIMITED REGULATION OF I F IN SINOATRIAL MYOCYTES. Emily J. Sharpe , Eric D. Larson, Catherine Proenza 1368-P os B oard B319 REGULATION OF ICA DURING SIMULATED ACUTE ISCHEMIA IN DEVELOPING CARDIOMYOCYTES EXPOSED TO HYPOXIA AND LOW PH. Jose C. Fernandez-Morales , Xiao-Hua Zhang, Hua Wei, Lars Cleemann, Martin Morad 1369-P os B oard B320 NON-LINEAR REDUCTION OF ION CURRENTS IN CULTURED CARDIAC MYOCYTES: CORRELATION WITH A LOSS OF T-TUBULES? Tanya Zeina, Reuben T. Mathew, Erica Freund, Brian K. Panama, Matthew Betzenhauser, Jacqueline A. Treat, Jonathan M. Cordeiro 1370-P os B oard B321 T-TUBULES IN MYOCYTES OF INTACT DOG LEFT AND RIGHT ATRIA. Gary L. Aistrup, Stephen Supple, Caleb Frank, Jasleen Singh, Shannon Tai, Laura Chicos, Anne Zhao, William Marszalec, Rishi Arora, AndrewWasserstrom 1371-P os B oard B322 CDO DEFICIENT MICE DISPLAY CARDIOMYOPATHY WITH ALTERATIONS IN CONNEXINS. Hyun-ji Kim , Myong-Ho Jeong, Young-Eun Leem, Jong-Sun Kang, Hana Cho

1372-P os B oard B323 LOSS OF PI3K-GAMMA SCAFFOLD FUNCTION CAUSES SEVERE ELECTRICAL REMODELING IN MICE VENTRICULAR MYOCYTES. Riccardo Rizzetto , Alexandra Jr Zahradnikova, Yueyi Wang, Alessandra Ghigo, Rodolphe Fischmeister, Emilio Hirsch, Jean- Pierre Benitah, Ana M. Gomez 1373-P os B oard B324 MASS SPECTROMETRY-BASED ANALYSIS OF THE PHOSPHO- PROTEOME FOR CARDIAC DYSSYNCHRONY AND RESYNCHRONIZATION THERAPY. Jonathan A. Kirk , Ronald J. Holewinski, Vidya Venkatraman, Eric Grote, David A. Kass, Jennifer E. Van Eyk 1374-P os B oard B325 MODULATION OF ACTION POTENTIAL ALTERNANS BY IKS IN MYOCARDIAL INFARCTION. Bum-Rak Choi, Tae Yun Kim , Mayara Grizotte-Lake, Jean Daley, Lorraine Schofield, Kamana Bist, Joseph Yammine, Yukiko Kunitomo, Yichun Lu, Xuwen Peng, Zhilin Qu, Gideon Koren 1375-P os B oard B326 A GUINEA PIG MODEL FOR HEART FAILURE-ASSOCIATED SUDDEN CARDIAC DEATH. Ting Liu , Deeptankar Demazumder, Brian O’Rourke 1376-P os B oard B327 IRON OVERLOAD PROMOTES ARRHYTHMIAS VIA ROS PRODUCTION AND MITOCHONDRIAL MEMBRANE POTENTIAL DEPOLARIZATION. Richard Gordan , Nadezhda Fefelova, Judith Gwathmey, Lai-Hua Xie 1377-P os B oard B328 FRET MEASUREMENTS OF CAMP DYNAMICS IN HL1 CELLS SUPPORT THE KEY ROLE OF CONSTITUTIVE AC ACTIVITY IN CARDIAC PACEMAKING. Evgeny Kobrinsky , Kirill V. Tarasov, Yelena S. Tarasova, Victor Maltsev, Steven J. Sollott, Edward G. Lakatta 1378-P os B oard B329 ABNORMALITIES IN TRANSMURAL VENTRICULAR ELECTROPHYSIOLOGY IN A HETEROZYGOUS SCN5A KNOCKOUT MOUSE MODEL REVEALED BY TWO-PHOTON MICROSCOPY. Allen Kelly , Tomas O. Stølen, Karin Solvang-Garten, Flavien Charpentier, Ulrik Wisløff, Godfrey L. Smith 1379-P os B oard B330 FEATURES OF OPTICAL MAPPING IN BLUE-GREEN AND NIR LIGHTS IN RABBIT HEART. Rūta Vosyliūtė , Regina Mačianskienė, Irma Martišienė, Antanas Navalinskas, Rimantas Treinys, Birutė Vaidelytė, Jonas Jurevičius 1380-P os B oard B331 COMPREHENSIVE ANALYSIS OF BEHAVIORAL VARIABILITY IN REAL AND SIMULATED POPULATIONS OF RABBIT LEFT VENTRICULAR CARDIOMYOCYTES. Ryan A. Devenyi , Victor Z. Rodriguez, Maria P. Hortigon-Vinagre, Godfrey L. Smith, Eric A. Sobie 1381-P os B oard B332 APPLICATION OF THE RIMARC ALGORITHM TO A LARGE DATA SET OF ACTION POTENTIALS AND CLINICAL PARAMETERS FOR RISK PREDICTION OF ATRIAL FIBRILLATION. Ursula Ravens , Deniz Katircioglu-Öztürk, Erich Wettwer, Claire Poulet, Simone Loose, Michael Knaut, Emre Oto, Ali Oto, H. Altay Güvenir

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland