Biophysical Society 59th Annual Meeting Program Guide

Actin Structure, Dynamics, and Associated Proteins (Boards B437-B454) 1486-P os B oard B437 ROLE OF H2 CALPONIN IN MYOBLAST DIFFERENTIATION, FUSION AND MYOGENESIS. Bin Wei , J.-P. Jin 1487-P os B oard B438 cpow mid - career travel awardee PALLADIN NUCLEATES ACTIN ASSEMBLY AND REGULATES CYTOSKELETON ARCHITECTURE. Ritu Gurung, Ravi Vattepu, Rahul Yadav, Moriah R. Beck 1488-P os B oard B439 UNRAVELING THE MYSTERY OF ATP HYDROLYSIS IN ACTIN FILAMENTS. Martin McCullagh , Marissa G. Saunders, Gregory A. Voth 1489-P os B oard B440 ACTIN TROPOMYOSIN ASSEMBLY INTERMEDIATES. Peyman Obeidy , Thomas L. Sobey, Elvis Pandzic, Philip R. Nicovich, Adelle Coster, Peter Gunning, Till Böcking 1490-P os B oard B441 TENSION AND CONSTRICTION OF THE CYTOKINETIC CONTRACTILE RING DEPEND ON ANCHORING OF RING COMPONENTS TO THE PLASMA MEMBRANE. Shuyuan Wang , Ben O’Shaughnessy 1491-P os B oard B442 MICRORHEOLOGY OF IN-VITRO ACTO-MYOSIN NETWORKS IN STEADY STATE. Adar Sonn-Segev 1492-P os B oard B443 COUPLING ARP2/3 COMPLEX-MEDIATED ACTIN BRANCHING AND MEMBRANE DEFORMATION BY THE EXOCYST COMPONENT EXO70. Wei Guo 1493-P os B oard B444 COARSE-GRAINED SIMULATIONS REVEAL MECHANISMS OF FISSION YEAST CYTOKINESIS. Lam T. Nguyen , Matthew T. Swulius, Mithilesh Mishra, Grant J. Jensen 1494-P os B oard B445 ACTIN MACROMOLECULES AND BUNDLES IN CELL- SIZED CONFINEMENT: FROM COLLECTIVE BEHAVIOR TO EMERGING NETWORKS. Siddharth Deshpande, Zoe Swank, Thomas Pfohl 1495-P os B oard B446 F-ACTIN HAS SLOW DYNAMICS AND CONCERTED MOVEMENT AS INDICATED BY H/D EXCHANGE RATE MAPPING. Devanand Kowlessur, Larry S. Tobacman 1496-P os B oard B447 CHARACTERIZATION AND STABILIZATION OF FASCIN- BUNDLED ACTIN FILAMENTS TRANSPORTED BY HEAVY MEROMYOSIN. Hideyo Takatsuki , Alf Månsson 1497-P os B oard B448 CRYO-EM OF ONE STATE OF F-ACTIN YIELDS A NEW ATOMIC FILAMENT MODEL. Vitold E. Galkin, Albina Orlova , Gunnar Schroder, Edward H. Egelman 1498-P os B oard B449 MECHANISMS OF FRNK INHIBITION OF FAK IN VASCULAR SMOOTH MUSCLE CELLS. Taylor J. Zak , Allan Samarel, Seth Robia

1475-P os B oard B426 THE POWER OUTPUT OF INTACT, ISOLATED RAT CARDIOMYOCYTES. Michiel Helmes , Aref Najafi, Jolanda van der Velden 1476-P os B oard B427 STORAGE USING BDM OR BLEBBISTATIN PRESERVES FUNCTIONAL MEASURES OF UNLOADED CARDIOMYOCYTES. Charles S. Chung , Charles Mechas, Kenneth S. Campbell 1477-P os B oard B428 RAPID, HIGH EFFICIENCE PURIFICATION OF MYOFILAMENT PROTEINS USING TOBACCO ETCH VIRUS PROTEASE. Mengjie Zhang , Jody L. Martin, Pieter P. De Tombe, Ramzi J. Khairallah 1478-P os B oard B429 STRUCTURAL EFFECTS OF CARDIAC TROPONIN T R92L AND TROPOMYOSIN D230N MUTANTS IN THE CARDIAC THIN FILAMENT. Mark T. McConnell , Lauren Grinspan, Jil Tardiff 1479-P os B oard B430 CONTRACTILE PROPERTIES OF MYOFIBRILS FROM HIPSC-DERIVED CARDIOMYOCYTES OF PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY. Josè Manuel Pioner , Alice Ward Racca, Xuan Guan, Lil Pabon, Mark Y. Jeong, Christian I. Childers, Jesse Macadangdang, Veronica Muskheli, Corrado Poggesi, Deok- Ho Kim, David L. Mack, Martin K. Childers, Charles E. Murry, Michael Regnier Smooth Muscle Mechanics, Structure, and Regulation (Boards B431-B436) 1480-P os B oard B431 AFM REVEALS AGE-DEPENDENT MICROMECHANICAL DEGRADATION OF CARDIOPULMONARY TISSUES IN A MOUSE MODEL OF MARFAN SYNDROME. Jia-Jye Lee , Satish Rao, Josephine Galatioto, Francesco Ramirez, Kevin D. Costa 1481-P os B oard B432 BRONCHIAL BUT NOT TRACHEAL SMOOTH MUSCLE IS HYPERCONTRACTILE IN AN EQUINE MODEL OF SEVERE ASTHMA. Oleg S. Matusovsky , Linda Kachmar, Gijs Ipgma, Nedjma Zitouni, Genevieve Bates, Jean-Pierre Lavoie, Anne-Marie Lauzon 1482-P os B oard B433 REDEFINING THE LATCH-STATE IN HUMAN AIRWAY SMOOTH MUSCLE. Gijs Ijpma , Linda Kachmar, Anne-Marie Lauzon 1483-P os B oard B434 KINETIC CHARACTERIZATION OF STABILIZED SMOOTH MUSCLE MYOSIN FILAMENTS. Brian D. Haldeman , Christine Cremo, Josh Baker 1484-P os B oard B435 VARYING THE NUMBER OF HEADS IN PHOSPHORYLATED SMOOTH MUSCLE MYOSIN FILAMENTS PROVIDES EVIDENCE FOR ATTACHMENT LIMITED KINETICS OF IN VITRO ACTIN- SLIDING VELOCITIES. Richard Brizendine , Diego Alcala, Brian Haldeman, Kevin Facemyer, Josh Baker, Christine Cremo 1485-P os B oard B436 THE STRUCTURE OF THE ACTIN-SMOOTH MUSCLE MYOSIN II COMPLEX IN THE RIGOR STATE. Zhong Huang

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland