Biophysical Society 59th Annual Meeting Program Guide

1597-P os B oard B548 MAPPING FUNCTIONAL GROUP REQUIREMENTS OF LIGANDS AT THE OCCLUDED BINDING POCKET OF β 2- ADRENERGIC G-PROTEIN COUPLED RECEPTOR USING SITE IDENTIFICATION BY LIGAND COMPETITIVE SATURATION SIMULATIONS. Sirish K. Lakkaraju , Wenbo Yu, Prabhu E. Raman, Alexander D. MacKerell Jr. 1598-P os B oard B549 INSIGHTS FROM ALL-ATOM MOLECULAR DYNAMICS SIMULATIONS OF 40 NUCLEOSOME CHROMATIN FIBER. Ramu Anandakrishnan , Saeed Izadi, Alexey V. Onufriev 1599-P os B oard B550 COMPUTATIONALLY PROJECTING THE INFLUENCE OF NUCLEIC ACID ON PATHWAYS OF NUCLEATION-LIMITED VIRUS CAPSID ASSEMBLY. Gregory R. Smith , Lu Xie, Russell Schwartz 1600-P os B oard B551 DOCKING TO THE HIGHLY FLEXIBLE ESTROGEN RECEPTOR LIGAND BINDING DOMAIN VIA MIXED-RESOLUTION MONTE CARLO. Sundar Raman Subramanian , Daniel M. Zuckerman 1601-P os B oard B552 TOWARDS THE SIMULATION OF A COMPLETE ATP SYNTHASE: UNRAVELLING THE STRUCTURAL BASIS OF THE ENZYME’S REVERSIBLE ACTION. Abhishek Singharoy , Klaus Schulten 1602-P os B oard B553 SIN MUTATIONS ALTER STRUCTURE AND DYNAMICS OF HUMAN MONONUCLEOSOMES. Suma Mohan S , Thomas C. Bishop, Vijayalakshmi Mahadevan 1603-P os B oard B554 QUINONE BINDING IN BACTERIAL PHOTOSYNTHETIC REACTION CENTER. Arpita Banerjee , Marilyn Gunner 1604-P os B oard B555 MOLECULAR DYNAMIC SIMULATION STUDIES ON LOLA AND LOLB PROTEINS IN E.COLI. Priyadarshini Murahari , Gautam Pennathur, Sharmila Anishetty 1605-P os B oard B556 THE ROLE OF THE ION DEHYDRATION PROCESS IN LOW AND HIGH CONDUCTANCE K CHANNELS. Romina V. Sepúlveda , Felipe Bravo-Moraga, Ignacio Diaz-Franulic, Daniel Aguayo, David Naranjo, Ramon Latorre, Fernando D. Gonzalez-Nilo 1606-P os B oard B557 COMPUTATIONAL DESIGN OF ALLOSTERIC INHIBITORS OF AKT AND SGK KINASES. D. S. Dalafave , R. E. Dalafave Optical Microscopy and Super-Resolution Imaging I (Boards B558-B586) 1607-P os B oard B558 AN AUTOMATED PROTOCOL FOR PERFORMANCE BENCHMARKING A WIDEFIELD FLUORESCENCE MICROSCOPE. Michael Halter , Elianna Bier, Paul C. DeRose, Gregory A. Cooksey, Steven J. Choquette, Anne L. Plant, John T. Elliott 1608-P os B oard B559 RESPIRATION RATE MEASUREMENTS OF SINGLE BACTERIAL CELLS. Michael C. Konopka

1609-P os B oard B560 DEVELOPMENT OF PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL (PBPK) OF CANCER TREATMENT IN MICE. Jeremy C. Bonor 1610-P os B oard B561 RAISING THE SPEED LIMIT ON 3D-3WAY FRET MICROSCOPY. Brandon L. Scott , Adam D. Hoppe 1611-P os B oard B562 STRETCHED, ORIENTED DNA ARRAYS (SODA) FOR FLUORESCENCE BASED SINGLE-MOLECULE EXPERIMENTS IN COMPLEX ENVIRONMENT. Eugeniu Ostrofet , Seungkyu Ha, Richard Janissen, Theo van Laar, Nynke Dekker 1612-P os B oard B563 DUAL-SWITCHING FRET (DSFRET) IMAGING BASED ON PHOTOSWITCHABLE DONOR-ACCEPTOR PAIR. Yingqi Wang , Ji Tang, Xiaodong Liu 1613-P os B oard B564 DYNAMIC TURNOVER OF FTSZ-RING IN LIVE CELL. Xinxing Yang , Christopher Herrick Bohrer, Jie Xiao 1614-P os B oard B565 COUNTING MOLECULES IN NON-MUSCLE MYOSIN II FILAMENTS. Xiaohu Wan 1615-P os B oard B566 Z-PROFILING OF CFTR OLIGOMERIZATION STATE DISTRIBUTIONS VIA SINGLE MOLECULE STEP PHOTOBLEACHING ANALYSIS IN EPITHELIAL CELLS. Jean-Francois Desjardins , Asmahan Abu-Arish, Amani Hariri, Hanadi F. Sleiman, Gonzalo Cosa, John W. Hanrahan, Paul W. Wiseman 1616-P os B oard B567 DIMERIZATION OF EPHA2 IN CELL MEMBRANES. Deo R. Singh , Chris King, Nisha R. Gupta, Matt Salotto, Kalina Hristova 1617-P os B oard B568 SINGLE MOLECULE ANALYSIS REVEALS COEXISTENCE OF STABLE SEROTONIN TRANSPORTER MONOMERS AND OLIGOMERS IN THE LIVE CELL PLASMA MEMBRANE. Andreas Anderluh, Enrico Klotzsch, Vivek Kumar, Amy H. Newman, Harald H. Sitte, Gerhard J. Schuetz 1618-P os B oard B569 RFP TAGS FOR LABELING SECRETORY PATHWAY PROTEINS. Mingshu Zhang , Xi Zhang, Lin Yuan, Pingyong Xu 1619-P os B oard B570 “DECORATING” CELLS WITH GENETICALLY ENCODED FLUORESCENT PROTEINS - WHAT COLOR SUITS YOUR EXPERIMENT BEST? Li-Chun Tu , Juahdi Monbo, Aviva Joseph, David B oard B571 CONFOCAL ABSORPTION MICROSCOPY OF BIOMOLECULES IN THE ATTO-MOLE RANGE. Alfons Schulte , Fatholah Salehi, Michael Sigman 1621-P os B oard B572 TESTING A DIFFUSION TRAP MODEL FOR STORE-OPERATED CALCIUM ENTRY BY SINGLE PARTICLE TRACKING. Minnie M. Wu , Elizabeth D. Covington, Richard S. Lewis Grunwald 1620-P os

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland