Biophysical Society 60th Annual Meeting

1184-Pos Board B161 INVESTIGATION OF THE CAS9 MEDIATED DNA CLEAVAGE USING TIME- LAPSE AFM IMAGING. Suleyman Ucuncuoglu , Ozgur Sahin 1185-Pos Board B162 DNA BINDING FLUORESCENT PROTEINS FOR THE DIRECT VISUALIZATION OF LARGE DNA MOLECULES. Seonghyun Lee , Kyubong Jo 1186-Pos Board B163 DIRECT OBSERVATION OF DNA OVERWINDING BY RVERSE GYRASE.  Taisaku Ogawa , Katsunori Yogo, Shou Furuike, Kazuo Sutoh, Akihiko Kikuchi, Kazuhiko Kinosita, Jr. 1187-Pos Board B164 BINDING OF THE SINGLE-STRANDED DNA BINDING PROTEIN (GP32) OF T4 BACTERIOPHAGE INDUCES POSITION-SPECIFIC LOCAL CONFORMA- TIONAL CHANGES IN DNA LATTICES THAT CAN BE MONITORED BY FLUO- RESCENT PROBES. Davis Jose , Miya M. Michael, Pablo Romano, Benjamin R. Camel, Katarina H. Meze, Neil P. Johnson, Marina Guenza, Andrew H. Marcus, Peter H. von Hippel 1188-Pos Board B165 AN ISING MODEL DESCRIBES HYSTERESIS IN A NOVEL FORM OF COOP- ERATIVE BINDING. Natalia N. Vtyurina , David Dulin, Margreet W. Docter, Anne S. Meyer, Nynke H. Dekker, Elio A. Abbondanzieri 1189-Pos Board B166 CONFORMATIONAL CHANGES IN HIV-1 GAG REGULATE ITS ASSEMBLY AND GENOME SELECTION.  Ioulia Rouzina 1190-Pos Board B167 RECOGNITION OF SPECIFIC URIDINES IN TRNA SUBSTRATES BY DIHY- DROURIDINE SYNTHASES. Huw Jenkins, Fiona Whelan, Daniel Peters, Robert Byrne, Andrey Konevega, Eugene Koonin, Fred Antson 1191-Pos Board B168 A SINGLE-MOLECULE FRET STRATEGY THAT ENABLES THE ORDERING THE PROXIMITIES OF YEAST SPECIFIC U1 PROTEINS TO THE 5 SPLICE SITE.  Jheng-Syong Wu , Tz-yun Chen, Sean Chang, Tien-Hsien Chang, Wei- Board B169 SINGLE STRANDED DNA TRANSLOCASES CAN PUSH SINGLE STRANDED DNA BINDING PROTEINS ALONG SINGLE STRANDED DNA.  Joshua E. Sokoloski , Alexander Kozlov, Roberto Galletto, Timothy M. Lohman 1193-Pos Board B170 FUSED IN SARCOMA (FUS) TARGETS NEURONAL G QUADRUPLEX CON- TAINING MRNAS. Damian McAninch , Mihaela-Rita Mihailescu 1194-Pos Board B171 PROTEIN PACKING CODE FOR DNA RECOGNITION BASED ON THE KNOB- SOCKET MODEL. Hyun Joo , Vivian Chen, Sruti Elson, Jerry Tsai 1195-Pos Board B172 E. COLI GYRASE FAILS TO NEGATIVELY SUPERCOIL DIAMINOPURINE-SUB- STITUTED DNA. Monica Fernandez-Sierra, Qing Shao, Chandler Fountain, Laura Finzi, David D. Dunlap 1196-Pos Board B173 SINGLE MOLECULE MEASUREMENTS OF DNA DECATENATION BY THE TOPOISOMERASE III-RECQ HELICASE COMPLEX. K. Maria Mills , Keir C. Neuman 1197-Pos Board B174 EXTRACTING ENZYME PROCESSIVITY FROM KINETIC ASSAYS.  Itay Barel , Frank L.H. Brown 1198-Pos Board B175 CPOW TRAVEL AWARDEE MODELING PROTEIN-RNA COMPLEXES. Adelene Sim , Jinglin Chen, Julie Bernauer hau Chang 1192-Pos

1199-Pos Board B176 SIGNIFICANCE OF STERIC BULK IN DNA THREADING INTERCALATION REVELAED THROUGH FORCE-DEPENDENT KINETICS. Andrew G. Clark , Thayaparan Paramanathan, Fredrik Westerlund, Per Lincoln, Micah McCauley, Ioulia Rouzina, Mark Williams 1200-Pos Board B177 SINGLE-MOLECULE CONFORMATIONAL DYNAMICS OF E. COLI DNA POLYMERASE I. Raymond Pauszek , Rajan Lamichhane, Ingemar Pedron, David Millar 1201-Pos Board B178 SENSING THE BINDING SITES OF RNAP HOLOENZYME ON λ DNA AT- TACHED TO A PROBE TIP WITH SOLID STATE NANOPORES. Harpreet Kaur , Santoshi Nandivada, Changbae Hyun, Tao Huang, Min Xiao, David S. McNabb, Jiali Li Membrane Physical Chemistry and Membrane Dynamics (Boards B179 - B207) 1202-Pos Board B179 POLYSTYRENE NANOPARTICLES ALTER THE STRUCTURE AND STABILITY OF MODEL CELL MEMBRANES. David Van Doren , Luke Cuculis, Shelli L. Frey 1203-Pos Board B180 NANOPARTICLE INTERACTIONS WITH GIANT VESICLES FABRICATED FROM INVERTED HEADGROUP LIPIDS. Lu Wang , Noah Malmstadt 1204-Pos Board B181 CARBON NANOSTRUCTURES INTERACTION WITH GIANT UNILAMELLAR VESICLES AS A CELLULAR MODEL. Carlos A. Moreno Aguilar , Verónica Pérez Luna, José Luis Arauz Lara, Said Eduardo Aranda Espinoza, Mildred Quintana Ruiz 1205-Pos Board B182 PLFE AS A LIPOSOMAL STABILIZING AGENT: A SHEAR STRESS STUDY.  Alexander Bonanno , Allison Andrews, Umme Ayesa, Servio Ramirez, Parkson Lee-Gao Chong 1206-Pos Board B183 UNDERSTANDING LIPID BILAYER DYNAMICS: RELATING BENDING AND THICKNESS FLUCTUATIONS TO MEMBRANE ELASTICITY. Michihiro Nagao , Rana Ashkar, Elizabeth Kellery, Robert Bradbury, Paul Butler 1207-Pos Board B184 BENDING MODULI OF TERNARY MIXTURE MODELS OF THE CELL PLASMA MEMBRANE. Rebecca Simpson , Sanjula Wickramasinghe, David Ackerman, Gerald Feigenson 1208-Pos Board B185 THE EFFECT OF PROTEINS AND LIPIDS ON MEMBRANE STIFFNESS. Philip W. Fowler, Anna Duncan, Jean Helie, Matthieu Chavent, Heidi Koldsø, Mark S.P. Sansom 1209-Pos Board B186 USING MOLECULAR DYNAMICS SIMULATIONS AND ATOMIC FORCE MICROSCOPY TO DETERMINE HOW α-SYNUCLEIN AFFECTS MEMBRANE MECHANICS. Benjamin E. Brummel , Jonathan Sachs 1210-Pos Board B187 LIPID-LIPID COUPLING TO MEMBRANE CURVATURE BY SIMULATION AND NMR. Alexander J. Sodt , Olivier Soubias, Klaus Gawrisch, Richard W. Pastor 1211-Pos Board B188 CURVED LIPID BILAYER MEMBRANES: PROTEIN MOTIONS AND HYDRODY- NAMIC TRANSPORT. Paul J. Atzberger

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