Biophysical Society 60th Annual Meeting

1748-Plat 10:45 am MOLECULAR EFFECTS OF DEAFNESS MUTATIONS IN ACTIN.  Lauren Jepsen, Karina Kruth, Peter Rubenstein, David Sept 1749-Plat 11:00 am TARGETED ACTIN DISASSEMBLY BY MICAL AND COFILIN.  Elena E. Grintsevich , Hunkar Gizem Yesilyurt, Shannon K. Rich, Ruei-Jiun Hung, Jonathan R. Terman, Emil Reisler 1750-Plat 11:15 am F-ACTIN FRAGMENTATION INDUCES DISTINCT MECHANISMS OF STRESS RELAXATION IN THE ACTIN CYTOSKELETON. Wonyeong Jung, Michael P. Murrell, Taeyoon Kim 1751-Plat 11:30 am THE EFFECT OF MULTIVALENT CATIONS ON MICROTUBULE-PROTEIN TAU ORDERING.  Chaeyeon Song , Peter Chung, Herbert P. Miller, Youli Li, Stuart C. Feinstein, Leslie Wilson, Cyrus R. Safinya 1752-Plat 11:45 am NOVEL MECHANISM OF REGULATION OF MICROTUBULE DYNAMICS BY TAU.  Rehan Ali, Christopher L. Berger 1753-Plat 12:00 pm SUPER-RESOLUTION IMAGING OF SLOWLY DEPOLYMERIZING MICRO- TUBULES REVEALS NO CURVED PROTOFILAMENTS WITH A LIFETIME LONGER THAN SECONDS.  Douglas S. Martin , Nicholas J. Carter, Robert A. Cross 1754-Plat 12:15 pm LOCAL ANCHORAGE OF KINETOCHORE-FIBERS TO THE MAMMALIAN SPINDLE PROVIDES MECHANICAL ISOLATION AND LOAD-BEARING RE- DUNDANCY. Mary W. Elting , Dylan B. Udy, Sophie Dumont 1755-Plat 12:30 pm SINGLE-MOLECULE INVESTIGATION OF THE DIFFUSIVE MICROTUBULE +TIP TRACKING PROTEIN EB1.  Benjamin J. Lopez, Megan T. Valentine Platform Protein-Lipid Interactions II 10:45 am - 12:45 pm, Room 502B Co-Chairs Zhiming Chen, University of Pennsylvania Durba Sengupta, National Chemical Laboratory, Germany 1756-Plat 10:45 am CROSSLINKING/MS STUDIES OF CHOLESTEROL INTERACTIONS WITH HUMAN α1 GLYCINE RECEPTOR.  Nicholas Ferraro , Emily Benner, Jeffry Madura, Michael Cascio 1757-Plat 11:00 am A THERMODYNAMIC STUDY OF THE EFFECTS OF CHOLESTEROL ON THE ACTIVITY OF ANTIMICROBIAL PEPTIDE PROTEGRIN-1.  Nishanth S. Iyengar , J. Michael Henderson, Tiffany Suwatthee, Indroneil Roy, Alan J. Waring, Ka Yee C. Lee 1758-Plat 11:15 am CONFORMATIONAL DYNAMICS OF GPCR DIMERS IS DEPENDENT ON MEMBRANE CHOLESTEROL.  Durba Sengupta , Xavier Prasanna, Amitabha Chattopadhyay 1759-Plat 11:30 am CHOLESTEROL PROMOTES THE PERIPHERAL BINDING OF RETROVIRAL PROTEINS TO LIPID BILAYERS. Milka Doktorova , Robert Dick, Frederick A. Heberle, Gerald W. Feigenson, Volker M. Vogt 1760-Plat 11:45 am ASSESSING THE MECHANISM BY WHICH A CHOLESTEROL RECOGNITION AMINO ACID CONSENSUS (CRAC) MOTIF RECOGNIZES MEMBRANE CHO- LESTEROL.  Evan Koufos , Angela C. Brown

No Abstract 11:53 pm X-RAYS AND ELECTRONS ILLUMINATE NEUROTRANSMITTER RECEPTOR STRUCTURE AND MECHANISM.  Eric Gouaux No Abstract 12:10 pm CHOLESTEROL, THE MOLECULE YOU THOUGHT YOU KNEW.  Philip Yeagle No Abstract 12:27 pm INTERPRETATION OF SOLUTION X-RAY SCATTERING BY EXPLICIT-SOLVENT MOLECULAR DYNAMICS.  Jochen Hub Platform Other Channels 10:45 am - 12:45 pm, Petree Hall D Co-Chairs Jorge Arreola, Universidad Autónoma de San Luis Potosí Inicio, Mexico Peter Pohl, Johannes Kepler University, Australia 1740-Plat 10:45 am MOLECULAR DETERMINANTS UNDERLYING THE PATHOGENIC MECHA- NISM OF KID SYNDROME ELICITED BY CX26G12R MUTATION.  Isaac E. García , Gustavo Contreras, Amaury Pupo, Bernardo Pinto, Ramón Latorre, Jorge E. Contreras, Agustín D. Martínez, Carlos González 1741-Plat 11:00 am THREE-DIMENSIONAL STRUCTURE OF INNEXIN GAP JUNCTION CHAN- NELS STUDIED BY ELECTRON CRYSTALLOGRAPHY.  Atsunori Oshima , Tomohiro Matsuzawa, Kazuyoshi Murata, Kazutoshi Tani, Yoshinori Fujiyoshi 1742-Plat 11:15 am ACCESS OF METAL IONS AND METHANETHIOSULFONATE REAGENTS TO THE CALCIUM-GATED CONNEXIN HEMICHANNEL PORE: IMPLICATIONS FOR THE LOCATION OF THE GATE. William I. Lopez , Jaya Ramachandran, Andrew L. Harris, Jorge E. Contreras 1743-Plat 11:30 am MEASURING PROTON DEPLETION IN THE VICINITY OF PROTON CHAN- NELS.  Leon D. Islas , Victor De la Rosa-Jimenez, Esteban Suarez, Gisela Rangel 1744-Plat 11:45 am ACID-INDUCED CHLORIDE CURRENT IN DISTAL CONVOLUTED TUBULE.  William C. Valinsky, Rhian M. Touyz, Alvin Shrier 1745-Plat 12:00 pm MODULATION OF THE CALCIUM-DEPENDENT CHLORIDE CHANNEL TMEM16A BY EXTRACELLULAR PROTONS.  Silvia Cruz-Rangel , José J. De Jesús-Pérez, Criss Hartzell, Patricia Pérez-Cornejo, Jorge Arreola 1746-Plat 12:15 pm UNUSUAL ION PATHWAY ARCHITECTURE OF THE DUAL-TOPOLOGY FLUO- RIDE CHANNEL FLUC.  Nicholas B. Last , Christopher Miller 1747-Plat 12:30 pm VOLTAGE SENSITIVITY OF THE BACTERIAL PROTEIN TRANSLOCATION CHANNEL.  Denis G. Knyazev , Roland Kuttner, Christine Siligan, Lukas Winter, Peter Pohl Platform Actin and Microtubules: Structure and Dynamics 10:45 am - 12:45 pm, Room 502A Co-Chairs David Sept, University of Michigan Megan Valentine, University of California, Santa Barbara

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