Biophysical Society 60th Annual Meeting

2291-Pos Board B435 SARCOMERE LENGTH DEPENDENT EFFECTS ON CA 2+ -INDUCED TRO- PONIN REGULATION WITHIN CHEMICALLY SKINNED CARDIAC MUSCLE FIBERS. King-Lun Li, R. John Solaro, Wenji Dong 2292-Pos Board B436 DESIGNING A HIGH AFFINITY CARDIAC TROPONIN ACTIVATOR. Fangze Cai , Monica Li, Sandra Pineda-Sanabria, Shorena Gelozia, Steffen Lindert, J. AndrewMcCammon, Frederick West, Brian Sykes, Peter Hwang Cytoskeletal-based Intracellular Transport (Boards B437 - B444) 2293-Pos Board B437 BROWNIAN DYNAMICS SIMULATION REVEALS FREEDOM OF MOTORS IN THE CARGO MEMBRANE CAN INFLUENCE CARGO DYNAMICS. Matthew J. Bovyn , Steven Gross, Jun Allard 2294-Pos Board B438 CONTROLLING VESICLE MOTION IN CORTICAL NEURONS WITH MAGNET- IC FORCES. Anja Kunze , Coleman Murray, Andy K. Tay, Dino Di Carlo 2295-Pos Board B439 THE ROLE OF THE MICROTUBULE CYTOSKELETON IN REGULATING INTRA- CELLULAR TRANSPORT. Linda Balabanian , Christopher L. Berger, Adam G. Board B440 MICROTUBULE GLIDING FORMATION ON CURVED SURFACES. Kaylee Cortes 2297-Pos Board B441 INTERNATIONAL TRAVEL AWARDEE COLLECTIVE EFFECTS OF MOTORS AND MICROTUBULES GEOMETRY IN GLIDING ASSAYS. Neha Khetan, Kunalika Jain, Anushree R. Chaphalkar, Chaitanya A. Athale 2298-Pos Board B442 MYOSIN VA MOTOR TEAMS NAVIGATE VESICLE CARGOS THROUGH 3D ACTIN FILAMENT INTERSECTIONS. Andrew T. Lombardo , Shane Nelson, M. Yusuf Ali, Kathleen Trybus, SamWalcott, David M. Warshaw 2299-Pos Board B443 3D MODEL OF VESICLES TRANSPORTED BY MYOSIN VA MOTOR TEAMS THROUGH ACTIN INTERSECTIONS PREDICTS EXPERIMENTAL DIRECTION- AL OUTCOMES. SamWalcott , Andrew T. Lombardo, Shane Nelson, M. Yusuf Ali, David M. Warshaw 2300-Pos Board B444 FORCE GENERATION BY MEMBRANE-ASSOCIATED MYOSIN-I. Serapion Pyrpassopoulos, Goker Arpag, Elizabeth A. Feeser, Henry Shuman, Erkan Tuzel , E. Michael Ostap Bacterial Mechanics, Cytoskeleton, and Motility (Boards B445 - B458) 2301-Pos Board B445 DYNAMICS OF REVERSIBILITY OF PRESSURE INDUCED CHANGES IN CELL MORPHOLOGY, CELL DIVISION, AND GENE EXPRESSION OF ESCHERICHIA COLI. Pradeep Kumar 2302-Pos Board B446 DYNAMICS OF PHENOTYPIC REVERSIBILITY OF BACTERIAL CELLS WITH OSCILLATING PRESSURES. Sudip Nepal , Pradeep Kumar 2303-Pos Board B447 INVESTIGATING THE MATERIAL PROPERTIES OF THE CAULOBACTER CRES- CENTUS ADHESIVE HOLDFAST. Alex Nyarko , Hazel Barton, Ali Dhinojwala Hendricks 2296-Pos

2279-Pos Board B423 APLIP1 CONTROLS THE PROCESSIVITY OF NEUREXIN AXONAL TRANS- PORT. Ulises Rey , Mehmet Ucar, Reinhard Lipowsky, Stephan Sigrist Cardiac Muscle Mechanics and Structure II (Boards B424 - B436) 2280-Pos Board B424 HIGH-SPEED, HIGH-PERFORMANCE REAL-TIME IMAGING OF PHYSI- OLOGICAL SARCOMERE DYNAMICS IN THE BEATING MOUSE HEART IN VIVO. Fuyu Kobirumaki-Shimozawa , Kotaro Oyama, Togo Shimozawa, Takashi Ohki, Takako Terui, Shin’ichi Ishiwata, Norio Fukuda 2281-Pos Board B425 IMAGINGS OF SARCOMERES IN RAT NEONATAL CARDIOMYOCYTES EX- PRESSING STRESS FIBER-LIKE STRUCTURES. Teruyuki Fujii 2282-Pos Board B426 OSCILLATORY BEHAVIOR IN MUSCLE MYOSIN. Lorenzo Marcucci , Takumi Washio, Toshio Yangida 2283-Pos Board B427 CROSS-BRIDGE GROUP ENSEMBLES DESCRIBING COOPERATIVITY IN THERMODYNAMICALLY CONSISTENT WAY. Mari Kalda , Pearu Peterson, Marko Vendelin 2284-Pos Board B428 CARDIAC LENGTH-DEPENDENT ACTIVATION: WEAK BINDING HYPOTHESIS TESTED BY A COMPUTATIONAL SARCOMERE MODEL. William C. Hunter , Alison L. Schroeder 2285-Pos Board B429 MODELING PREDICTS NON-MONOTONIC DEPENDENCE OF MYOFILA- MENT CA 2+ SENSITIVITY ON TROPOMYOSIN STIFFNESS. Lorenzo R. Sewanan , Stuart Campbell 2286-Pos Board B430 A FRET INVESTIGATION ON THE EFFECTS OF TROPOMYOSIN D230N AND CARDIAC TROPONIN T R92L MUTANTS ON THE TROPOMYOSIN OVER- LAP STRUCTURE. Mark T. McConnell , Lauren Tal Grinspan, Benjamin Schwartz, Ofer Z. Fass, Jayant James Jayasundar, Jil C. Tardiff 2287-Pos Board B431 MOLECULAR MECHANISMS OF CARDIOMYOPATHY-CAUSING TNT MUTANTS IMPLICATED IN INTERACTIONS WITH TROPOMYOSIN. Binnu Gangadharan , Souhrid Mukherjee, Margaret S. Sunitha, Ashvini Dubey, R Sowdhamini, James A. Spudich, John A. Mercer 2288-Pos Board B432 CA 2+ -SENSITIVITY AND ELEMENTARY STEPS OF THE CROSS-BRIDGE CYCLE IN PAPILLARY MUSCLE FIBERS FROM THE TROPONIN C (TNC)-A8V KNOCK-IN MOUSE, WHICH EXHIBITS HYPERTROPHIC CARDIOMYOPATHY (HCM). Masataka Kawai, Tarek Karam, Jose R. Pinto 2289-Pos Board B433 HCM ASSOCIATED CARDIAC TROPONIN I MUTATIONS ALTER CARDIAC TROPONIN FUNCTION, CONTRACTILE PROPERTIES AND MODULATION BY PKA MEDIATED PHOSPHORYLATION. Yuanhua Cheng , Lindert teffen, An-Yue Tu, Maria V Razumova, Luping Xie, Lucas Oxenford, Andrew D. McCulloch, J AndrewMcCammon, Michael Regnier 2290-Pos Board B434 THE ROLE OF CALCIUM AFFINITY AND C-I INTERACTION IN LENGTH-DE- PENDENT ACTIVATION.  Jordan M. Klaiman , Maria V. Razumova, Joseph D. Powers, Cameron W. Turtle, Farid Moussavi-Harami, Todd E. Gillis, Michael Reniger

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