Biophysical Society 60th Annual Meeting

Caterina Ricci , Marche Polytechnic University, Italy 1813-Plat STRUCTURE AND STABILITY OF HSP60 AND GROEL IN SOLUTION. Zhaokun Zhou , University of York, United Kingdom 2460-Pos, B604 COMBINED MAGNETO-OPTICAL TWEEZERS AND SUPER-RESOLUTION FLUORESCENCE IMAGING FOR PROBING DYNAMIC SINGLE-MOLECULE TOPOLOGY OF DNA, AND PROTEIN MACHINES THAT MANIPULATE Matteo Aldeghi , University of Oxford, United Kingdom 2687-Pos, B64 PREDICTING LIGAND SELECTIVITY ACROSS BROMODOMAIN FAMILIES. Annemie Biesemans , KU Leuven, Belgium 2553-Plat CONTROLLING THE NANOSCOPIC CONFINEMENT OF ENZYMES INSIDE CLYA NANOPORES FOR SINGLE-PROTEIN STUDIES. Marco Castello , Italian Institute of Technology, Genoa 3199-Pos, B576 BOOST YOUR MICROSCOPE BY EXPLORING NEW DIMENSIONS. Tao-Hsin Chang , University of Oxford, United Kingdom 2912-Pos, B289 STRUCTURAL AND FUNCTIONAL INSIGHTS OF NORRIN MIMICS WNT FOR SIGNALLING. Pilar Cossio , Max Planck Institute of Biophysics, Germany 3126-Pos, B503 ON ARTIFACTS IN SINGLE-MOLECULE FORCE SPECTROSCOPY. Wei Ding , Queen Mary University of London, United Kingdom 2826-Pos, B203 ATOMISTIC AND COARSE-GRAINED MOLECULAR SIMULATIONS OF MIXED LAMELLAR/NONLAMELLAR LIPID MEMBRANES. Bárbara Gomes , Institute of Molecular Medicine, University of Lisbon, Portugal 2566-Plat THE MECHANISM OF HIV ENTRY INHIBITION BY 25-HYDROXYCHOLESTEROL. Deepak K. Hansda , Indian Institute of Technology, Bombay 3046-Pos, B423 EFFECT OF BRANCHING ON FORCE-VELOCITY CURVES AND LENGTH FLUCTUATIONS OF ACTIN NETWORKS. Rikke Holm , Aarhus University, Denmark 3101-Pos, B478 RESCUE OF NA+ AFFINITY IN ASPARTATE-928 MUTANTS OF NA+,K+- ATPASE BY SECONDARY MUTATION OF GLUTAMATE-314. Ishutesh Jain , Indian Institute of Technology, Bombay 3045-Pos, B422 DYNAMIC INSTABILITY EMERGES FROM MICROMECHANICS AND CHEMICAL KINETICS OF MICROTUBULE PROTOFILAMENTS. Yadira Medina Guevara , University of Sao Paulo, Brazil 2664-Pos, B41 MODELING PROTEIN- DNA INTERACTION ON GROUNDS OF QUANTUM ENTANGLEMENT. DNA TOPOLOGY. Wednesday

Yury A. Nikolaev , Victor Chang Cardiac Research Institute, Australia 3015-Pos, B392 MECHANOSENSITIVITY OF TRPC6 ION CHANNEL RECONSTITUTED IN THE LIPOSOMES. Michele Oneto , Italian Institute of Technology, Genoa 3198-Pos, B575 3D MULTICOLOR STED NANOSCOPE A SUPER-RESOLUTION APPROACH TO MAMMALIAN PHOTORECEPTOR. SS Soumya , Indian Institute of Technology, Bombay 3082-Pos, B459 COHERENT MOTION OF MONOLAYER SHEETS UNDER ACTIVE AND PASSIVE CONFINEMENT: FROM BUILD-UP TO CONSEQUENCE. PROFESSIONAL OPPORTUNITIES FOR WOMEN Sunday Jana Broecker , University of Toronto, Canada 208-Plat ADVANCES IN IN SITU X-RAY CRYSTALLOGRAPHY OF MEMBRANE PROTEINS. Ana M. Melo , University of Pennsylvania 197-Plat DETERMINING A TOPOLOGICAL MODEL FOR TAU BOUND TO TUBULIN HETERODIMERS. Rebecca J. Moen , Minnesota State University, Mankato 763-Pos, B543 DETECTING STRUCTURAL CHANGES IN MYOSIN USING BIFUNCTIONAL SPIN LABELS. Sonia Troeira Henriques , University of Queensland, Australia 399-Pos, B179 STRUCTURE-ACTIVITY RELATIONSHIP STUDIES REVEAL THAT THE SPIDER TOXIN PROTX-II HAS UNUSUAL MEMBRANE-BINDING PROPERTIES AND INHIBITS NAV1.7 CHANNEL AT THE MEMBRANE SURFACE. Monday Nabanita Das , University of Colorado, Boulder 1084-Pos, B61 ACTIVATION OF TOLL-LIKE RECEPTOR 5 IMMUNE SIGNALING BY HMGB1. Sherry S.W. Leung , Simon Fraser University, Canada 1228-Pos, B205 DEVELOPMENT OF LIPID-BASED DRUG DELIVERY SYSTEMS FOR GENE THERAPY: PHYSICOCHEMICAL CHARACTERIZATION OF CHARGED LIPID INTERACTIONS. Sabine Lotteau , University of Leeds, United Kingdom 1319-Pos, B296 SIMVASTATIN HAS PROFOUND EFFECTS ON SARCOPLASMIC RETICULUM CA 2+ LEAK IN SKELETAL BUT NOT CARDIAC MUSCLE: A MECHANISM FOR MYOPATHY. Gaelle Robin , University of California, Davis 1568-Pos, B545 FRAGILE X~ASSOCIATED TREMOR~ATAXIA SYNDROME: LINKING CA 2+ DYSREGULATION AND DNA DAMAGE RESPONSES.

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