Biophysical Society 60th Annual Meeting

Molecular Biophysics Subgroup 9:15 am - 1:45 pm, Room 502A

2:10 pm short talks by postdoctoral awardees PHASE SEPERATION OF DISORDERED PROTEINS INTO LIQUID DROPLETS WITH TUNABLE PROPERTIES. Shana Elbaum-Garfinkle . A GOLDILOCKS PREDICAMENT FOR VON WILLEBRAND FACTOR MEDI- ATED PLATELET ADHESION. Alexander Tischer (SEE LATE ABSTRACTS) 14-Subg 2:40 pm STRUCTURE AND DYNAMICS OF INTRINSICALLY DISORDERED PROTEINS FROM A PHYSICS-BASED MODEL.  Jeetain Mittal 15-Subg 3:05 pm DISCOVERY AND CHARACTERISATION OF NOVEL FUNCTIONAL MODULES IN INTRINSICALLY DISORDERED REGIONS.  Norman Davey 3:30 pm coffee break 16-Subg 3:50 pm SIMULTANEOUS TUNING OF ACTIVATION AND REPRESSION IN INTRINSIC DISORDER-MEDIATED ALLOSTERY.  Vincent J. Hilser 17-Subg 4:15 pm DISORDERED CDK SUBSTRATES ACT AS MULTI-INPUT SIGNAL PROCES- SORS TO CONTROL THE KEY DECISION POINTS IN THE CELL CYCLE. Mart Loog 18-Subg 4:40 pm SLOW INTERNAL DYNAMICS AND STRUCTURAL PROPERTIES OF IDPS OF THE CT FAMILY: COMPARING AMYLOID AND NON-AMYLOID VARIANTS.  Sara M. Vaiana 19-Subg 5:05 pm STRUCTURAL AND FUNCTIONAL ANALYSES OF IDPS BY HIGH-SPEED AFM IMAGING.  Toshio Ando , Noriyuki Kodera 5:30 pm introduction of keynote speaker 2 20-Subg 5:35 pm SEQUENCE CONSTRAINTS ON FOLDING AND BINDING.  Susan Marqusee 6:20 pm closing remarks Biopolymers in vivo Subgroup 10:45 am – 6:45 pm, Room 501ABC Subgroup Chair Martin Gruebele, University of Illinois at Urbana Champaign TRANSLATION DYNAMICS AND NASCENT PROTEOME BEHAVIOR 10:45 am business meeting 11:45 am lunch break 1:15 pm introduction by the program co-chairs, chris- tian kaiser and ed o’brien 21-Subg 1:20 pm MONITORING TRANSLATION IN SPACE AND TIME WITH RIBOSOME PRO- FILING.  Jonathan Weissman No Abstract 1:50 pm PROBING DIMENSIONALITY BEYOND THE LINEAR SEQUENCE OF MRNA.  Zoya Ignatova 22-Subg 2:20 pm LOW ENERGY BARRIERS AND A DYNAMIC CONTACT NETWORK BETWEEN RIBOSOMAL SUBUNITS ENABLE RAPID TRNA TRANSLOCATION.  Lars V. Bock, Christian Blau, Andrea C. Vaiana, Helmut Grubmuller No Abstract 2:50 pm DYNAMICS OF TRANSLATION.  Joseph Puglisi

Subgroup Chair Justin Benesch, University of Oxford, United Kingdom

S A T U R D A Y

NEW METHODS FOR STUDYING THE STRUCTURAL DYNAMICS OF MACROMOLECULES

9:15 am

opening remarks

No Abstract 9:20 am STRUCTURE, DYNAMICS, AND FREE ENERGY LANDSCAPES BY NMR.  Dorothee Kern No Abstract 10:05 am TIME-RESOLVED X-RAY CRYSTALLOGRAPHY.  Arwen Pearson No Abstract 10:35 am HIGH-SPEED SCATTERING FOR VISUALIZING NANOMETRIC PROTEIN COMPLEXES.  Philipp Kukura No Abstract 11:05 am ASSEMBLING MACROMOLECULAR COMPLEXES WITH EVOLUTIONARY- BASED INTEGRATIVE MODELING. Matteo Dal Peraro 11:35 am coffee break and subgroup business meeting 10-Subg 12:05 pm CHARTING CELLULAR LANDSCAPES IN MOLECULAR DETAIL BY IN SITU CRYO-ELECTRON TOMOGRAPHY.  Jürgen Plitzko , Julia Mahamid, Benja- min D. Engel, Sahradha Albert, Miroslava Schaffer, Jan Arnold, Yoshiyuki Fukuda, Radostin Danev, Wolfgang Baumeister No Abstract 12:35 am NEWMICROFLUIDIC APPROACHES FOR STUDYING THE SELF-ASSEMBLY AND MISASSEMBLY OF PROTEINS.  Tuomas Knowles No Abstract 1:05 pm DYNAMICS OF VIRAL STRUCTURES - FROMMASS SPECTROMETRY TO X-RAY FREE-ELECTRON LASERS.  Charlotte Uetrecht 1:35 pm close Society of General Physiologists Council Meeting 10:00 am - 1:00 pm, Room 510 Intrinsically Disordered Proteins Subgroup 10:00 am - 6:30 pm, Room 515A Subgroup Chair Elizabeth Rhoades, Yale University 10:00 am business meeting 12:30 pm opening remarks and introduction of keynote speaker 1 11-Subg 12:35 pm INTRINSICALLY DISORDERED PROTEINS IN NEURODEGENERATION.  Markus Zweckstetter 12-Subg 1:20 pm BALANCING ORDER AND DISORDER IN NEURODEGENERATION AND NEUROTRANSMISSION.  David Eliezer 13-Subg 1:45 pm ATOMIC-RESOLUTION IN-CELL NMR ANALYSIS OF ALPHA-SYNUCLEIN IN MAMMALIAN CELLS REVEALS DISORDERED MONOMER.  Phil Selenko

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