Biophysical Society 60th Annual Meeting

Symposium: New and Notable Petree Hall C Co-Chairs: Vasanthi Jayaraman, University of Texas Health Science Center, and E. Michael Ostap, University of Pennsylvania STRUCTURE OF A TRPV2 ION CHANNEL, Seok-Yong Lee CRYO-EM STRUCTURE OF A MICRONUTRIENT TRANSPORTER WITH UNUSAUL ARCHITECTURE. Filippo Mancia STRUCTURAL DYNAMICS OF K CHANNEL GATING REVEALED BY SINGLE MOLECULE FRET. Colin Nichols THE MOTIONS AND INTERACTIONS IN MISMATCH REPAIR TAGET SEARCH DYNAMICS ARE REVEALED BY LIVE-CELL SINGLE-MOLECULE MICROSCOPY. Julie Biteen INTEGRATIVE STRUCTURAL BIOLOGY OF TETRAHYMENA TELOMERASE. Juli Feigon INTRINSICALLY DISORDERED PROTEINS AS PHYSICAL DRIVERS OF MEMBRANE TRAFFIC. Jeanne C. Stachowiak FLOPPY BUT NOT SLOPPY: DECODING PLASTICITY IN THE DARK PROTEOME OF THE NUCLEAR TRANSPORT MACHINERY. Edward Lemke

S U N D A Y

10:45 am–12:45 pm

Symposium: Computational and Experimental Approaches to Protein Design Chair: Rama Ranganathan, University of Texas, Southwestern MAPPING CONSTRAINTS ON PROTEIN EVOLUTION . Jesse Bloom UNCOVERING AND REPROGRAMMING G PROTEIN COUPLED RECEPTOR SIGNALING. Patrick Barth DESIGNING PEPTIDE INHIBITORS OF ANTI-APOPTOTIC BCL-2 FAMILY PROTEINS . Amy E. Keating PROTEIN MECHANICS: THE LINK BETWEEN STRUCTURE AND FUNCTION. Rama Ranganathan

Petree Hall D

10:45 am–12:45 pm

10:45 am–12:45 pm Platform: Cryo-Electron Microscopy

Room 502A

10:45 am–12:45 pm Platform: Cell Mechanics, Mechanosensing, and Motility I

Room 502B

10:45 am–12:45 pm Platform: TRP Channels

Room 515A

10:45 am–12:45 pm Platform: Protein Assembly and Function

Room 515B

10:45 am–12:45 pm Platform: Membrane Active Peptides and Toxins

Room 501ABC

10:45 am–12:45 pm Platform: Cardiac Smooth and Skeletal Muscle Electrophysiology

Room 511ABC

11:30 am–1:00 pm Undergraduate Student Pizza "Breakfast"

Room 406AB

11:30 am–5:00 pm Colleges in the Community Day

Room 406AB

12:00 pm–1:00 pm International Travel Awardee Luncheon

Room 404AB

Room 518

12:00 pm–1:00 pm Career Center Workshop

Creating and Using an Effective CV/Résumé

12:15 pm–2:15 pm Public Affairs Committee Meeting

Room 506

1:00 pm–2:30 pm The World Outside the Lab: Many Ways to Use Your PhD Skills in Industry

Room 403A

1:00 pm–3:00 pm Graduate & Postdoc Institution Fair

West Hall

1:45 pm–3:00 pm Snack Break

West Hall

1:45 pm–3:45 pm Poster Presentations and Late Posters

West Hall

2:00 pm–3:30 pm Teaching Science Like We Do Science

Room 408A

Room 518

2:30 pm–3:30 pm Career Center Workshop Networking for Nerds 2:30 pm–4:00 pm Transparency, Reproducibility, and the Progress of Science

Room 411

3:30 pm–5:00 pm Early Careers Committee Meeting

Room 506

Room 518

4:00 pm–5:00 pm Career Center Workshop

Ten Tough Industrial Interview Questions (and Ten Pretty Good Responses)

Symposium: Signaling Complexes and Dynamics

Petree Hall C

Chair: Hao Wu, Harvard Medical School STRUCTURAL ELUCIDATION OF INNATE IMMUNITY . Hao Wu MECHANISM OF JAK2 ACTIVATION BY THE ARCHETYPE CLASS I CYTOKINE RECEPTOR, THE GROWTH HORMONE RECEPTOR. Andrew J. Brooks MECHANISM AND FUNCTIONS OF PLATELET MECHANOSENSING. Renhao Li CONFORMATIONAL PLASTICITY AND DRUGGABILITY OF MEMBRANE-BOUND K-RAS. Alemayehu A. Gorfe

4:00 pm–6:00 pm

10