Biophysical Society 60th Annual Meeting

248-Pos Board B28 NMR STRUCTURAL/FUNCTIONAL CHARACTERIZATION OF AN ONCOGEN- IC MUTANT OF CAMP-DEPENDENT PROTEIN KINASE A: PRKACA-DNA- JB1. Adak N. Karamafrooz , Jonggul Kim, Geoffrey Li, Sanford M. Simon, Susan S. Taylor, Gianluigi Veglia 249-Pos Board B29 STUDY ON THE CONFORMATIONAL CHANGE OF C-SRC TYROSINE KINASE: TARGETED MOLECULAR DYNAMICS SIMULATION. Sangwook Wu Protein-Small Molecule Interactions I (Boards B30 - B48) 250-Pos Board B30 BIOPHYSICAL STUDIES ON THE INTERACTION OF THIONINE GOLD NANOCONJUGATE TO SERUM ALBUMIN. Puja Paul , G. SURESH KUMAR, S. Chandra Bhattacharyya 251-Pos Board B31 COMPUTATIONAL ASSESSMENT OF TRIMETHOPRIM RESISTANCE IN DI- HYDROFOLATE REDUCTASE. Haleh Abdizadeh, Omer Acar, Tandac Furkan Guclu, Yusuf Talha Tamer, Tugce Altinusak Batur, Erdal Toprak, Ali Rana Atilgan, Canan Atilgan 252-Pos Board B32 INTERACTIONS BETWEEN A CLASSICAL ALLOSTERIC PROTEIN AND A STRONG EFFECTOR REVISITED. Shunsuke Sakurai, Daiki Sawada, Takashi Yonetani, Antonio Tsuneshige 253-Pos Board B33 HUMAN SERUM ALBUMIN-[RU(PHEN)3]2+ COMPLEX FORMATION STUDIED BY OPTICAL SPECTROSCOPIES. Zuzana Jurasekova , Veronika Huntosova, Dominik Belej, Pavol Miskovsky, Daniel Jancura 254-Pos Board B34 MULTIMERIZATION OF SOLUTION-STATE PROTEINS BY WATER SOLUBLE PORPHYRINS. Daniel R. Marzolf , Aidan M. McKenzie, Alexander C. Hudson, Oleksandr Kokhan 255-Pos Board B35 NANOSCALE MEASUREMENTS OF BIOCHEMICAL INTERACTIONS AT THE SURFACE OF OPTICALLY TRAPPED PARTICLES. Wooten D. Simpson III , Volkmar Heinrich 256-Pos Board B36 CHARACTERIZATION OF THE INFLUENCE OF A SMALL MOLECULE ON A RAS-RELATED PROTEIN-PROTEIN INTERACTION. Djamali Muhoza, Paul D. Adams 257-Pos Board B37 CATION-SPECIFIC INFLUENCES ON THE SOLVATION AND SOLVENT ACCES- SIBILITY OF ALANINE-RICH PEPTIDES. Taylor P. Light , Gina MacDonald 258-Pos Board B38 BIOPHYSICAL AND MOLECULAR INVESTIGATION OF THE INTERACTION BETWEEN ENTEROLACTONE AND HUMAN SERUM ALBUMIN. Bahareh Bigdeli, Behdad Delavari, Samaneh Samaei Daryan, Ali Akbar Saboury, Bahram Goliaei 259-Pos Board B39 POLYSACCHARIDE CROWDER SHOWS OPTIMAL AFFINITY FOR SEMI-OPEN STATE OF MALTOSE BINDING PROTEIN. Archishman Ghosh , Huan X. Zhou 260-Pos Board B40 EFFECT OF A COSOLVENT IN BINDING EVENTS OF HYDROPHOBIC MOL- ECULES. AN EXPERIMENTAL AND NUMERICAL STUDY. Caroline Senac, Patrick Fuchs, Wladimir Urbach, Nicolas Taulier 261-Pos Board B41 ATOMIC MECHANISMS OF STABILIZING AND DESTABILIZING CO-SOL- VENTS ON PROTEIN STABILITY. Cristiano L. Dias , Zhaoqian Su

262-Pos Board B42 FCS ON PROTEINS IN CROWDED ENVIRONMENTS. Alyazan Albarghash , Daryan Kempe, Niklas Ole Junker, Birgit Simone Hillebrecht, Friedemann Melchior Landmesser, Jörg Fitter 263-Pos Board B43 MODELING MACROMOLECULAR CROWDING THROUGH TRANSLATIONAL AND ROTATIONAL DIFFUSION OF SMALL MOLECULAR PROBES. Megan Currie , Brenden Berry, Taylor Ward, Erin D. Sheets, Ahmed A. Heikal 264-Pos Board B44 EFFECT OF CO-SOLUTES ON MODEL REACTION EQUILIBRIA: MIGHT CHANGES IN THE FREE ENERGY OF BULK WATER BE THE UNDERLYING CAUSE? Daryl K. Eggers 265-Pos Board B45 EXPLORATION OF WEAK INTERACTIONS BETWEEN FOLATE AND GLYCINE- BETAINE. Purva P. Bhojane , Michael R. Duff, Elizabeth E. Howell 266-Pos Board B46 QUANTIFYING INTERACTIONS BETWEEN BIOCHEMICAL FUNCTIONAL GROUPS AND WITH HOFMEISTER SALT IONS IN WATER. Xian Cheng , Lixue Cheng, Irina Shkel, Ben Knowles, Kevin Connor, Evan Buechel, Cristen Molzahn, AndrewMcclyman, David Lambert, Hunter Cochran, Thomas Jr. Record 267-Pos Board B47 A PROTEIN EXPRESSION SYSTEM FOR EVALUATING CATION-PI AND PI-PI INTERACTION IN PROTEINS. Jinfeng Shao, Andy-Mark W.H. Thunnissen, Jaap Broos 268-Pos Board B48 STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THREE UNDERCHAR- ACTERIZED FIMBRIAL ADHESINS. Roger D. Klein , Kevin O. Tamadonfar, Jerome S. Pinkner, Karen W. Dodson, Scott J. Hultgren Protein Dynamics and Allostery I (Boards B49 - B71) 269-Pos Board B49 THE STRUCTURAL AND DYNAMIC EFFECTS OF INHIBITOR BINDING TO PROTEIN KINASE C βII. Shashank Jariwala , Sivaraj Sivaramakrishnan, Barry J. Grant 270-Pos Board B50 MOLECULAR DYNAMICS SIMULATION AND MARKOV STATE MODEL REVEAL IRREGULAR METASTABLE CONFORMATION AND ALLOSTERY IN DNAJB-PKAC. Yingjie Wang , Alessandro Cembran, Jiali Gao, Gianluigi Veglia, Susan S. Taylor, Sanford M. Simon 271-Pos Board B51 A SYSTEMS APPROACH TO UNDERSTANDING THE ALLOSTERIC MECHA- NISM OF PYRUVATE KINASE M2.  Jamie A. Macpherson 272-Pos Board B52 ROLE OF THE CENTRAL STALK IN THE ROTARY-CHEMICAL COUPLING AND TORQUE GENERATION OF F1-ATPASE. Shayantani Mukherjee , Arieh Board B53 PROTEIN-LIGAND INTERACTIONS THROUGH THE COMPUTATIONAL MICROSCOPE: ALLOSTERY IN A CANONICAL SIGNALING DOMAIN. Robert D. Malmstrom , Alexandr P. Kornev, Susan S. Taylor, Rommie E. Amaro 274-Pos Board B54 MAPPING ALLOSTERY IN THE TWO DOMAIN CONSTRUCTS OF PDZ3 AND SH3 WITH ARTIFICIAL DOMAINS. Kirubakaran Palani , Lucie Pfeiferová, Jiří Vondrášek Warshel 273-Pos

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