Biophysical Society 60th Annual Meeting

Cell Mechanics, Mechanosensing, and Motility I (Boards B446 - B464) 666-Pos Board B446 HIGH SPEED, HIGH RESOLUTION IMAGING OF FLUCTUATIONS AT THE LEADING EDGE OF MOTILE CELLS. Rikki M. Garner , Julie Theriot 667-Pos Board B447 SEPARATING CILIARY BEATING FORCE INTO DYNEIN-DRIVEN FORCE AND AXONEME-INTRINSIC BENDING FORCE BY 3-D TRACKING MICROS- COPY. Takanobu A. Katoh , Koji Ikegami, Nariya Uchida, Toshihito Iwase, Tomoko Masaike, Mitsutoshi Setou, Takayuki Nishizaka 668-Pos Board B448 VERTICAL NANOPILLARS AS PROBES FOR IN SITU NUCLEAR MECHANO- TRANSDUCTION. Hsin-Ya Lou , Lindsey Hanson, Wenting Zhao, Yi Cui, Bianxiao Cui 669-Pos Board B449 HIGH FREQUENCY MICRORHEOLOGY OF LIVING CELLS. Felix Rico , Annafrancesca Rigato, Simon Scheuring 670-Pos Board B450 EXAMINING SPATIO-TEMPORAL DYNAMICS OF CELL-SUBSTRATE LINKERS DURING CELL MIGRATION USING POLYMER-TETHERED LIPID MULTI- BILAYERS OF ADJUSTABLE STIFFNESS. Yifan Ge, Kent Shilts, Yu-Hung Lin, Lena Lautscham, Ben Fabry, Wolfgang Goldmann, Christoph A. Naumann 671-Pos Board B451 THE PHYSICAL ORIGINS OF CELL TRANSIT THROUGH MICROFLUIDIC CON- STRICTIONS. Kendra Nyberg , Amy Rowat 672-Pos Board B452 STUDY ON THE REGULATION OF CELL MORPHOLOGY BY MATRIX NANO- TOPOGRAPHY IN 3D ENVIRONMENT.  Jingjing Han , Kenghui Lin, Lock Yue Chew 673-Pos Board B453 FOCAL ADHESION FORMATION AND REORGANIZATION ON NANOPAT- TERNED SURFACES. Emma J. Mah , Elena I. Liang, Albert F. Yee, Michelle A. Digman 674-Pos Board B454 CELLULAR CONTRACTILE FORCES MEASURED A MULTI-WELL SILICONE DEVICE REVEAL PHYSICAL FORCES THAT CONTROL CELL MIGRATION IN PHYSIOLOGY AND DISEASE. Haruka Yoshie 675-Pos Board B455 MOLECULAR TENSION SENSORS FOR PROBING THE MECHANICAL AND CHEMICAL ROLES OF DISTINCT INTEGRIN CLASSES. Steven J. Tan , Armen H. Mekhdjian, Alice C. Chang, Masatoshi Morimatsu, Alexander R. Dunn 676-Pos Board B456 DYNAMIC MONITORING OF CELL MECHANICAL PROPERTIES USING PRO- FILE MICROINDENTATION. Lionel Guillou , Avin Babataheri, Pierre-Henri Puech, Abdul Barakat, Julien Husson 677-Pos Board B457 DISSECTING THE ROLE AND REGULATION OF MECHANICAL FORCE AT THE T-APC SYNAPSE USING ATOMIC FORCE MICROSCOPY. Kenneth H. Hu , Manish J. Butte 678-Pos Board B458 ‘OPTICAL SHAKING’ OF RED BLOOD CELLS: A STRATEGY TO MEASURE CELL-FLUID COUPLING WITH OPTICAL TWEEZERS. Carla Zensen , Isis E. Fernandez Buelvas, Oliver Eickelberg, Theobald Lohmüller, Jochen Feldmann

652-Pos Board B432 INITIAL SEPARATION OF POLES TO FORM A BIPOLAR SPINDLE IS A RAPID AND IRREVERSIBLE PROCESS. Allen Y. Leary , Elena Nazarova, Shannon Sim, Eileen O’Toole, Paul Francois, Jackie Vogel 653-Pos Board B433 EDUCATION TRAVEL AWARDEE OXIDATIVE STRESS IN MYOCARDIAL INFARCTION DISRUPTS MICRO- TUBULE TRAFFICKING, REDUCING TRANSIENT OUTWARD CURRENT DENSITY. Benjamin Drum , Can Yuan, Lei Li, Linda Wordeman, L. Fernando Board B434 THREE-DIMENSIONAL STRUCTURES ASSOCIATED WITH PHOTORECEP- TOR CILIA BY CRYO-ELECTRON TOMOGRAPHY. Zhixian Zhang , Feng He, Michael F. Schmid, Theodore G. Wensel 655-Pos Board B435 STUDYING THE EFFECTS OF MODIFIED TUBULIN C-TERMINAL TAILS ON KATANIN SEVERING ACTIVITY. Corey E. Reed 656-Pos Board B436 MOLECULAR DISSECTION OF THE TUBULIN C-TERMINAL TAILS BY NMR. Kathryn Wall, Maria Pagratis, Geoffrey Armstrong, Chad Pearson, Loren Hough 657-Pos Board B437 BRIDGING LENGTH SCALES TO STUDY POLYMER ASSEMBLY: UTILIZING BAYESIAN ANALYSIS OF FRET TO MEASURE MICROTUBULE NUCLE- ATION. Bryan Kaye , Daniel J. Needleman 658-Pos Board B438 STRUCTURAL BASIS OF MICROTUBULE POLYMERASES IN ACCELERATING TUBULIN POLYMERIZATION VIA MULTIPLE TOG DOMAINS. Stanley Nithianantham, Brian D. Cook, Fred Chang, Jawdat Al-Bassam 659-Pos Board B439 KINESIN-CARGO MOTILITY IN RANDOMMICROTUBULE NETWORKS.  Julianne Flowers , Mehmet Kaplan 660-Pos Board B440 EFFECT OF ACTIVE KINESIN MOTOR DENSITY ON MICROTUBULES DURING SELF-ASSEMBLY OF SPOOLS. Amanda Tan , Dail Chapman, Linda Hirst, Jing Xu 661-Pos Board B441 POST-TRANSLATIONAL MODIFICATION IN MICROTUBULE ARRAYS EXHIB- ITS SPATIAL PATTERNS THAT CAN ACT AS A SIGNAL TO TIGHTLY LOCALIZE MOTOR-DRIVEN CARGO. Abdon Iniguez , Jun F. Allard 662-Pos Board B442 LABEL-FREE IMAGING OF MICROTUBULES WITH SUBNANOMETER PRECISION USING INTERFEROMETRIC SCATTERING MICROSCOPY.  Joanna Andrecka , Jaime Ortega-Arroyo, Robert Cross, Philipp Kukura 663-Pos Board B443 DEFORMABILITY OF MICROTUBULES: AN ATOMISTIC COMPUTATIONAL STUDY. Ondrej Kucera , Daniel Havelka, Marco A. Deriu, Michal Cifra 664-Pos Board B444 EFFECTS OF LATTICE SEGMENTATION ON MICROTUBULE MECHAN- ICS. Scott A. Erickson , Naoto Isozaki, Jennifer Ross, Taviare Hawkins 665-Pos Board B445 IS MICROTUBULE RIGIDITY PROPORTIONAL TO PROTOFILAMENT NUM- BER? Brandon J. Harris Santana 654-Pos

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