Biophysical Society 60th Annual Meeting

909-Plat 8:45 am CALSEQUESTRIN DEPOLYMERIZES WHEN CA 2+ CONCENTRATION DECAYS IN THE SARCOPLASMIC RETICULUM OF SKELETAL MUSCLE.  Carlo Manno , Lourdes Figueroa, Dirk Gillespie, Eduardo Rios 910-Plat 9:00 am SHEET-LIKE REMODELING OF THE T-SYSTEM OF VENTRICULAR CARDIO- MYOCYTES IN HEART FAILURE.  Thomas Seidel , Martin Tristani-Firouzi, Craig H. Selzman, Frank B. Sachse 911-Plat 9:15 am DIFFUSION PROPERTIES OF CARDIAC T-TUBULAR SYSTEM. Marina Scardigli, Claudia Crocini , Cecilia Ferrantini, Raffaele Coppini, Chiara Tesi, Elisabetta Cerbai, Corrado Poggesi, Francesco S. Pavone, Leonardo Sacconi 912-Plat 9:30 am MICROTUBULE-DEPENDENT ALTERATIONS TO MECHANICAL PROPERTIES AND MECHANOTRANSDUCTION IN SKELETAL MUSCLE.  Jaclyn P. Kerr , Guoli Shi, W Jonathan Lederer, Kelley M. Virgilio, Sylvia S. Blemker, Stuart S. Martin, Roberto Raiteri, Christopher W. Ward 913-Plat 9:45 am CALCIUM ENTRY UNITS: EXERCISE-DEPENDENT FORMATION OF NEW SR-TT JUNCTIONS CONTAINING STIM1 AND ORAI1 IN MUSCLE.  Simona Boncompagni, Antonio Michelucci, Laura Pietrangelo, Robert T. Dirksen, Feliciano Protasi 914-Plat 10:00 am RYANODINE RECEPTOR ACTIVITY REGULATES THE LEVELS OF CA 2+ EXTRU- SION AND STORE-OPERATED CA 2+ ENTRY IN SKELETAL MUSCLE.  Tanya R. Cully, Rocky H. Choi, Thomas R. Shannon, Bradley S. Launikonis Platform DNA Structure and Dynamics 8:15 am - 10:15 am, Room 511ABC Co-Chairs Vincent Croquette, LPS-ENS Research University, France Catherine Tardin, Institute of Pharmacology and Structural Biology, France 915-Plat 8:15 am REVISITING SEQUENCING BY HYBRIDIZATION AT THE SINGLE MOLECULE LEVEL USING THE UNZIPPING ASSAY.  Vincent Croquette , Saurabh Raj, Jean-François Allemand, David Bensimon, Jean-Baptiste Boulé 916-Plat 8:30 am MODELING SECONDARY STRUCTURAL ELEMENTS IN PROGRAMMED DNA ASSEMBLIES.  Keyao Pan , Mark Bathe 917-Plat 8:45 am THE OVERSTRETCHING TRANSITION OF DIAMINOPURINE SUBSTITUTED TRIPLY HYDROGEN-BONDED DNA.  Daniel T. Kovari , Matteo Cristofalo, David Dunlap, Laura Finzi 918-Plat 9:00 am THREE DIMENSIONAL DYNAMICS AND FLUCTUATIONS OF DNA-NANO- GOLD DIMERS BY INDIVIDUAL-PARTICLE ELECTRON TOMOGRAPHY.  Lei Zhang , Dongsheng Lei, Jessica M. Smith, Huimin Tong, Xing Zhang, Paul Alivisatos, Gang Ren 919-Plat 9:15 am BRANCHPOINT STRUCTURE OF DNA THREEWAY JUNCTIONS.  Anita Toulmin, Michael J. Morten , Tara Sabir, Laura E. Baltierra-Jasso, Peter McGlynn, Gunnar F. Schröder, Brian Smith, Steven W. Magennis 920-Plat 9:30 am DYNAMICS OF HUMAN TELOMERIC G-QUADRUPLEX PROBED BY SINGLE MOLECULE FLUORESCENCE-FORCE SPECTROSCOPY.  Jaba Mitra , Thuy T.M. Ngo, Taekjip Ha

921-Plat 9:45 am PROBING A LABEL-FREE LOCAL BEND IN DNA BY SINGLE MOLECULE TETHERED PARTICLE MOTION.  Annaël Brunet, Sébastien Chevalier, Nicolas Destainville, Manoel Manghi, Philippe Rousseau, Maya Sahi, Laurence Salome, Catherine Tardin 922-Plat 10:00 am QUANTIFYING THE ION ATMOSPHERE OF UNFOLDED, SINGLE-STRANDED NUCLEIC ACIDS.  David R. Jacobson , Omar A. Saleh CPOW Committee Meeting 8:30 am - 10:30 am, Room 408A Exhibitor Presentation Sophion together with Biolin Scientific 9:30 am - 11:00 am, Room 505 Pioneering Ion Channels - Expanding the Boundaries of Automated Patch Clamp Recent advances in automated patch clamp for voltage and ligand gated ion channels with emphasis on NMDA, cardiac safety and induced plu- ripotent stem cells Speakers Timm Danker, NMI, Germany Automated Patch Clamp on Crdiac Ion Channels and Multiwell MEA Recordings on Human iPSC-derived Cardiomyocytes: a Complementary Approach for Predictable Proarhytmia Assessments Caterina Virginio, Aptuit NMDA Receptors: Meaningful Biophysical and Pharmacological Studies to Redefine Ligands Properties Denise Franz, University of Rostock, Germany Electrophysiological Characterization of Human Induced Ppluripotent Stem Cell-derived Dopaminergic Neurons on the QPatch Career Center Workshop Ten Tough Industrial Interview Questions (and Ten Pretty Good Responses) 10:00 am - 11:00 am, Room 518 You’ve been invited to interview with that drug development company that you’ve always wanted to work for. You’ve soaked up the details of the position description. You are confident in your ability to do the job, as well as answer any/all technical questions during the interview process. The day is yours…until…that first question catches you by surprise and your confidence begins to wilt. Be prepared for those non-technical ques- tions that you will almost certainly hear at some point, know why they are asked, and learn what a good (if not great) response to each question might be by attending this workshop. Exhibits 10:00 am - 5:00 pm, West Hall Coffee Break 10:15 am - 11:00 am, West Hall

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