Biophysical Society 60th Annual Meeting

955-Plat 11:45 am PROBING THE STRUCTURE AND BINDING OF KCNE1 TO THE VOLTAGE- GATED POTASSIUM CHANNEL KCNQ1 USING PULSED EPR SPECTROSCOPY. Gary A. Lorigan , Indra D. Sahu, Andrew Craig, Rongfu Zhang, Robert M. McCarrick 956-Plat 12:00 pm STRUCTURAL DETERMINANTS AND BINDING PROPERTIES OF THE NEU- RITE OUTGROWTH INHIBITOR (NOGO). Melanie J. Cocco , Ali Alhoshani, Verna Vu, D’Artagnan Greene 957-Plat 12:15 pm STRUCTURE AND DYNAMICS OF COMPLEXES OF INTERLEUKIN-8 AND ITS RECEPTOR CXCR1 IN PHOSPHOLIPID BILAYERS BY SOLID-STATE NMR.  Sang Ho Park , Anna De Angelis, Jasmina Radoicic, Sabrina Berkamp, Zheng Long, Stanley J. Opella 958-Plat 12:30 pm FUNCTIONAL, DYNAMIC AND STRUCTURAL UNDERSTANDING OF M2 PROTON CHANNEL FROM INFLUENZA A AND ITS INHIBITION.  Timothy A. Cross , Riqiang Fu, E. Vindana Ekanayake, Yimin Miao, Joana Paulino, Wright Anna, Jian Dai, Huan-Xiang Zhou Platform ON THE FORCE-GENERATING CAPACITY OF DISASSEMBLING MICROTU- BULES.  Jonathan W. Driver, Elisabeth Geyer, Luke M. Rice, Charles L. Asbury 960-Plat 11:00 am A STRUCTURAL MODEL OF THE MITOTIC KINESIN-6 MECHANOCHEMICAL CYCLE.  Joseph Atherton, I-Mei Yu, Steven S. Rosenfeld, Anne Houdusse, Carolyn A. Moores 961-Plat 11:15 am EDUCATION TRAVEL AWARDEE KINETICS OF NUCLEOTIDE-DEPENDENT STRUCTURAL TRANSITIONS IN THE KINESIN-1 HYDROLYSIS CYCLE.  Keith J. Mickolajczyk , Nathan C. Deffenbaugh, Jaime Ortega-Arroyo, Joanna Andrecka, Philipp Kukura, William O. Hancock 962-Plat 11:30 am DIRECT OBSERVATION OF THE ALLOSTERIC CONFORMATIONAL CHANGE OF KINESIN-1 USING GOLD NANOROD AND ITS IMPLICATION FOR HEAD- HEAD COORDINATION.  Yamato Niitani, Sawako Enoki, Hiroyuki Noji, Ryota Iino, Michio Tomishige 963-Plat 11:45 am IMPACTS OF MICROTUBULE STRUCTURAL DEFECTS ON KINESIN-BASED TRANSPORT. Winnie H. Liang, Qiaochu Li, K Faysal, Stephen J. King, Ajay Gopinathan, Jing Xu 964-Plat 12:00 pm ENGINEERING NOVEL ACTIN-BASED MOLECULAR MOTORS FROM THE MICROTUBULE-BASED MOTOR DYNEIN.  Akane Furuta, Kazuhiro Oiwa, Hiroaki Kojima, Kenya Furuta 965-Plat 12:15 pm TWO LEVELS OF MYOSIN-IIA DYNAMICS IN CELLS: TURNOVER OF FILA- MENTS AND SELF-ORGANIZATION OF FILAMENT STACKS.  Shiqiong Hu , Kinjal Dasbiswas, Zhenhuan Guo, Yee-Han Tee, Visalatchi Thiagarajan, Ronen Zaidel-Bar, Pascal Hersen, Samuel Safran, Alexander D. Bershadsky 966-Plat 12:30 pm Cytoskeletal Motor Proteins 10:45 am - 12:45 pm, Room 501ABC Co-Chairs Carolyn Moores, Birkbeck College, United Kingdom Jing Xu, University of California, Merced 959-Plat 10:45 am

AN OPTOGENETIC METHOD FOR CONTROLLING FULL-LENGTH MYOSIN VI THROUGH ITS CARGO BINDING DOMAIN.  Alexander R. French , Ronald S. Rock, Tobin R. Sosnick Platform Single-Molecule Spectroscopy 10:45 am - 12:45 pm, Room 511ABC Co-Chairs TESTING THE PHYSICAL THEORY OF FOLDING AS DIFFUSIVE MOTION OVER AN ENERGY LANDSCAPE USING TRANSITION PATH ANALYSIS OF SINGLE-MOLECULE FOLDING TRAJECTORIES.  Krishna P. Npane , Ajay P. Manuel, John Lambert, Michael Woodside 968-Plat 11:00 am 3D TRACKING SINGLE MOLECULE FLUORESCENCE ENERGY TRANSFER MEASUREMENTS.  Aaron Keller, Matt DeVore, Dung Vu, Tim Causgrove, James Werner 969-Plat 11:15 am QUANTITATIVE PROTEIN KINETICS FROM SM-FRET TIME TRACES.  Sonja Schmid , Markus Goetz, Thorsten Hugel 970-Plat 11:30 am INFLUENCE OF THE BACKGROUND IN SINGLE MOLECULE FRET TIRF MI- CROSCOPY.  Søren Preus, Lasse Lava Hildebrandt, Victoria Birkedal 971-Plat 11:45 am A MULTISPOT CONFOCAL PLATFORM FOR HIGH-THROUGHPUT FREELY DIFFUSING SINGLE-MOLECULE FRET STUDIES.  Antonino Ingargiola, Eitan Lerner, SangYoon Chung, Angelo Gulinatti, Ivan Rech, Massimo Ghioni, Shimon Weiss, Xavier Michalet 972-Plat 12:00 pm INTERNATIONAL TRAVEL AWARDEE FARFRET: EXTENDING THE RANGE IN SINGLE-MOLECULE FRET EXPERI- MENTS BEYOND 10 NM.  Georg Krainer , Andreas Hartmann, Michael Schlierf 973-Plat 12:15 pm COMBINING SINGLE-MOLECULE TECHNIQUES WITH MICROFLUIDICS FOR PROTEIN ANALYSIS.  Christopher Taylor , Tuomas Knowles, David Klenerman 974-Plat 12:30 pm INTERNATIONAL TRAVEL AWARDEE APPLICATION OF THE SPLIT-FLCS METHOD TO THE DETECTION OF NANOSCALE DIFFUSION IN 3D IN LIVE CELLS.  Luca Lanzano , Lorenzo Scipioni, Melody Di Bona, Paolo Bianchini, Ranieri Bizzarri, Francesco Cardarelli, Giuseppe Vicidomini, Alberto Diaspro Career Center Workshop Leveraging Social Media for Networking and Career Advancement 11:30 am - 12:30 pm, Room 518 More and more recruiters, job decision-makers and hiring managers are using the web to find and research potential candidates. How can you make sure that you are not only found, but are ahead of the pack? In this session, we will discuss how decision-makers use LinkedIn and Facebook, and how you can use LinkedIn to establish yourself as a leader in your field, enhance your research reputation, and seek out and take advantage of innovative opportunities. We will demonstrate how to create a win- ning LinkedIn profile, and how to use its multitude of features (such as joining and commenting in groups) to generate solid leads for your career. Victoria Birkedal, Aarhus University, Denmark Sonja Schmid, University of Freiburg, Germany 967-Plat 10:45 am

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