Biophysical Society 60th Annual Meeting

1130-Pos Board B107 STRUCTURAL CHARACTERIZATION OF THE FULL LENGTH CRGA PROTEIN FOUND IN MYCOBACTERIUM TUBERCULOSIS. Yiseul Shin , Huajune Qin, Malini Rajagopalan, Timothy A. Cross 1131-Pos Board B108 INVESTIGATING THE ROLE OF TRANSMEMBRANE DOMAIN CYSTEINE RESIDUES IN THE ORGANIZATION OF TNF RECEPTORS. Tiffany L. Senkow , Andrew K. Lewis, Jonathan N. Sachs 1132-Pos Board B109 THE LIPOPROTEIN BAMB FACILITATES FOLDING AND INSERTION OF OUT- ER MEMBRANE PROTEIN A (OMPA) INTO LIPID MEMBRANES DEPENDING ON BILAYER THICKNESS. Lisa Gerlach, Jörg H. Kleinschmidt 1133-Pos Board B110 DETERMINATION OF THE INTERACTION OF γ-SECRETASE WITH ITS βCTF SUBSTRATE. Ayse Julius 1134-Pos Board B111 MEASURING LARGE MEMBRANE PROTEIN DIMERIZATION IN LIPID BILAYERS BY FORSTER RESONANCE ENERGY TRANSFER. Venkatramanan Krishnamani , Kacey Mersch, Rahul Chadda, Ankita Chadda, Janice L. Board B112 PROBING STRUCTURE AND DYNAMICS OF TRANSMEMBRANE ALPHA HE- LICES OF THE S21 PINHOLIN PROTEIN USING ELECTRON PARAMAGNETIC RESONANCE SPECTROSCOPY. Daniel L. Drew 1136-Pos Board B113 COMPLEX FOLDING PATHWAYS OF BACTERIORHODOPSIN REVEALED BY 1-μS-RESOLUTION FORCE SPECTROSCOPY. Matthew G. W. Siewny , Hao Yu, Devin T. Edwards, Aric W. Sanders, Thomas T. Perkins 1137-Pos Board B114 NEUTRON SCATTERING REVEALS PROTEIN FLUCTUATIONS IN GPCR ACTIVATION. Suchithranga M. D. C. Perera , Utsab Shrestha, Debsindhu Bhowmik, Udeep Chawla, Andrey V. Struts, Xiang-qiang Chu, Michael F. Brown 1138-Pos Board B115 CONFORMATIONAL CHANGES OF THE MULTIDRUG TRANSPORTER P-GLYCOPROTEIN IN SOLUTION AND LIPID DISCS. Leo Mok, Maria-Elena Zoghbi, Douglas J. Swartz, Anukriti Singh, Greg Fendley, Guillermo A. Altenberg, Ina Urbatsch 1139-Pos Board B116 INSIGHTS INTO THE STABILITY OF GPCRS IN DETERGENT MICELLES.  Sangbae Lee , Supriyo Bhattacharya, Allen Mao, Reinhard Grisshammer, Christopher Tate, Nagarajan Vaidehi 1140-Pos Board B117 MONITORING GPCR CONFORMATIONAL CHANGES DURING AGONIST RE- LEASE IN REAL-TIME: EVIDENCE THAT TRANSMEMBRANE HELIX 6 (TM6) MOVEMENT IN RHODOPSIN LAGS BEHIND RETINAL RELEASE. Christopher T. Schafer , David L. Farrens 1141-Pos Board B118 RETINAL CHROMOPHORE STRUCTURE IN META-II RHODOPSIN REVEALED BY SOLID-STATE 2 H NMR AND MOLECULAR MODELING. Andrey V. Struts , Xiaolin Xu, Trivikram R. Molugu, Michael C. Pitman, Samira Faylough, Charitha Guruge, Carolina Nascimento, Nasri Nesnas, Michael F. Brown 1142-Pos Board B119 INTERNATIONAL TRAVEL AWARDEE UNDERSTANDING STRUCTURAL AND FUNCTIONAL STABILITY OF TWO RHOMBOID PROTEASES: HIGLPG AND PSAARA. Rashmi Panigrahi , Elena Arutyunova, Pankaj Panwar, Katharina Gimpl, Sandro Keller, Joanne Lemieux Robertson 1135-Pos

1143-Pos Board B120 EDUCATION TRAVEL AWARDEE INFLUENCE OF FAMILIAL PARKINSON’S DISEASE MUTATIONS ON MITOCHONDRIAL LOCALIZATION AND SECONDARY STRUCTURE OF PINK1. Stephania Irwin , Rashmi Panigrahi, Elena Arutyunova, Nicolas Touret, M. Joanne Lemieux 1144-Pos Board B121 STRUCTURAL BASIS FOR KCNQ1 LONG-QT SYNDROME DISEASE CAUSING MUTATIONS. Keenan C. Taylor , Hui Huang, Brett Kroncke, Charles Sanders 1145-Pos Board B122 ENERGY COUPLING MECHANISMS AND LIPID-MEDIATED SUBUNIT INTERACTIONS OF THE MITOCHONDRIAL PROTEIN TRANSPORT MACHIN- ERY. Nathan N. Alder , Ketan Malhotra, Murugappan Sathappa, Shivangi Nangia, Tyler Daman, Dejana Mokranjac, Eric May Transcription (Boards B123 - B137) 1146-Pos Board B123 PAUSING IN ESCHERICHIA COLI TRANSCRIPTION INITIATION. Eitan Lerner , Sangyoon Chung, Benjamin Allen, Wang Shuang, Lee J. Jookyung, Lu Winson Shijia, Grimaud Wilson Logan, Antonino Ingargiola, Yazan Alhadid, Sergei Borukhov, Terence Strick, Dylan J. Taatjes, Shimon Weiss 1147-Pos Board B124 WALK AND CHECK ALONG A VIRAL RNA POLYMERASE TRANSCRIPTION ELONGATION PATH.  Jin Yu 1148-Pos Board B125 TRANSCRIPTION FACTOR CLUSTERING IN LIVE YEAST CELLS.  AdamWollman , Sviatlana Shashkova, Erik Hedlund, Stefan Hohmann, Mark C. Leake 1149-Pos Board B126 E.COLI RNA POLYMERASE ACTIVITY UNDER CROWDING. SangYoon Chung , Eitan Lerner, Yan Jin, Yazan Alhadid, Soohong Kim, Charles M. Knobler, WilliamM. Gelbart, Shimon Weiss 1150-Pos Board B127 LIVE CELL SINGLE MOLECULE BINDING OF TRANSCRIPTION FACTORS IN LIVING CELLS. CHARACTERIZING P53 LATENCY. Emanuela Jacchetti, Paolo Rainone, Tiziana Daniele, Tacchetti Carlo, Davide Mazza 1151-Pos Board B128 NANOSCALE PROBING OF THE P53 TUMOR SUPPRESSION TRANSCRIP- TION MACHINERY. Robert A. Coleman, Sameer K. Singh, Chunte S. Peng, Michael Cianfrocco, Zhengjian Zhang, William Rice, Edward Eng, Wei-Li Liu 1152-Pos Board B129 RAPID LONG RANGE SLIDING OF RNA DEPENDENT RNA POLYMERASES ON VIRAL GENOME TEMPLATES VISUALIZED BY PHOTOACTIVATABLE LOCALIZATION MICROSCOPY. Xiaolin Tang , Mourad Bendjennat, Saveez Board B130 PPI RELEASE FOLLOWED BY DNA TRANSLOCATION STUDIED FROM ATOM- ISTIC SIMULATIONS OF T7 RNA POLYMERASE TRANSCRIPTION. Chao E , Lin-Tai Da, Baogen Duan, Shaogui Wu, Jin Yu 1154-Pos Board B131 REGULATION OF THE BDNF MRNA 3’ UTR ON THE RNA LEVEL. Brett A. DeMarco , Mihaela-Rita Mihailescu, Snezana Stefanovic 1155-Pos Board B132 SUBNUCLEAR SPATIAL STRUCTURING OF CHROMATIN AND POLYMERASE II DURING TRANSCRIPTION ACTIVATION OF THE ZEBRAFISH ZYGOTIC GENOME. Lennart Hilbert , Vasily Zaburdaev, Nadine Vastenhouw Saffarian 1153-Pos

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