Biophysical Society 61st Annual Meeting | Program Guide

Protein Structure and Conformation III (Boards B1–B30) 1681-Pos Board B1 PROBING SUBSTRATE SEQUESTRATION IN CARRIER PROTEINS USING VIBRATIONAL SPECTROSCOPY LABELS. Caroline A. McKeon , Samuel C. Epstein 1682-Pos Board B2 IDENTIFICATION OF FLUOXETINE-SEROTONIN TRANSPORTER INTERAC- TIONS USING CROSSLINKING-MASS SPECTROMETRY (CX-MS). Elizabeth Castellano 1683-Pos Board B3 INSIGHTS INTO SUBSTRATE UNFOLDING AND ALLOSTERIC REGULATION OF INSULIN DEGRADING ENZYME. Felicia H. Jiang , Wei-Jen Tang, Esmael J. Haddadian 1684-Pos Board B4 SECA FUNCTIONS IN VIVO AS A 1M6N-LIKE DIMER TO PROMOTE PRO- TEIN TRANSPORT. Tithi Banerjee 1685-Pos Board B5 COMPARISON OF POLARIZABLE CONTINUUM & QUANTUMMECHAN- ICS/MOLECULAR MECHANICS MODELS WITH SERIES OF TRIPEPTIDES (AXA). Allen Walker, Lillian Zhu, Esmael Jafari Haddadian, Ahmed Lakhani 1686-Pos Board B6 IDENTIFICATION OF KEY STRUCTURAL FEATURES DETERMINING THE BINDING OF ALPHA GLOBIN AND ENDOTHELIAL NITRIC OXIDE SYN- THASE. TC Stevenson Keller IV , Nicole K. Swope, Brant E. Isakson, Linda Board B7 MOLECULAR LEVEL INSIGHT INTO A UNIQUE SURFACE PROTEIN GLY- COSYLATION PATHWAY: STRUCTURE OF THE ACTINOMYCES ORIS LCP ENZYME THAT MEDIATES SURFACE PROTEIN GLYCOSYLATION. Brendan R. Amer , Michael R. Sawaya, Brandon Liauw, Janine Fu, Hung Ton-That, Robert T. Clubb 1688-Pos Board B8 RATIONAL DEVELOPMENT OF HBV CAPSID INHIBITORS AIDED BY MOLECULAR DYNAMICS. Maksym Korablyov, Anna Pavlova, Christophe Chipot, James C. Gumbart 1689-Pos Board B9 CHARACTERIZATION OF THE FULL-LENGTH, HUMAN BECLIN-1 PURIFIED FROM ESCHERICHIA COLI . Matthew Ranaghan , Colin Garvie, Doug Dan- iels, Beth Levine, Jose Perez 1690-Pos Board B10 DIFFERENT COVALENT IMMOBILIZATION STRATEGIES INFLUENCING THE FIBRONECTIN’S CONFORMATION AND BIOACTIVITY. Stephanie Vanslambrouck , Pascale Chevallier, Andree-Anne Guay-Begin, Gaetan Laroche 1691-Pos Board B11 International Travel Awardee STRUCTURAL DYNAMICS IN THE MYOSIN 7A SINGLE Α-HELIX DO- MAIN. Matthew Batchelor , Marcin Wolny, Peter J. Knight, Emanuele Paci, Arnout P. Kalverda, Michelle Peckham 1692-Pos Board B12 Education Travel Awardee PROTEIN ENERGY NETWORK MODELS TO CLASSIFY AND PREDICT FUNCTIONALLY LINKED INTERFACES OF PROTEINS FROM FUNCTIONALLY UNCORRELATED INTERFACES.  Isha D. Mehta , Brian W. Beck Columbus 1687-Pos

1693-Pos Board B13 ASSEMBLY OF A MULTIMERIC ALLOSTERIC PROTEIN FROM ITS ISOLATED COMPONENTS CHARACTERIZED BY ISOTHERMAL TITRATION CALORIM- ETRY (ITC). Antonio Tsuneshige 1694-Pos Board B14 BUILDING A BETTER PHOSPHOLAMBAN: CHARACTERIZING AND OPTI- MIZING THE STRUCTURAL DYNAMICS OF DOMAIN IB PLN MUTANTS TO TUNE SERCA FUNCTION. Kim N. Ha , Mara Exline, Sarah E. Nelson, Gianluigi Veglia 1695-Pos Board B15 CHARGE NEUTRALIZATION, NOT SALT BRIDGES, STABILIZES ALPHA HELI- CES IN REPEATING BLOCKS OF ACIDIC AND BASIC RESIDUES. Ammon E. Posey , Tyler S. Harmon, Rohit V. Pappu 1696-Pos Board B16 MULTI-STATE MODELING OF BIOMOLECULES BY SATISFACTION OF SPATIAL RESTRAINTS FROM SINGLE-PARTICLE ELECTRON MICROSCOPY IMAGES.  Ilan E. Chemmama , Charles H. Greenberg, Andrej Sali 1697-Pos Board B17 IDENTIFICATION AND CHARACTERIZATION OF A REPRESSED TROPONIN I-LIKE EPITOPE STRUCTURE IN THE C-TERMINAL REGION OF TROPONIN T. Taylor Heilig , J.-P. Jin 1698-Pos Board B18 NMR STUDIES OF CONFORMATIONAL SELECTION OF HNRNP H ON RNA SPLICING. Liang-Yuan Chiu , Srinivas Penumutchu, Blanton S. Tolbert 1699-Pos Board B19 CHARACTERIZATION OF A NOVEL FRET PROBE IN A CROWDED ENVIRON- MENT USING TIME-RESOLVED ANISOTROPY. Hannah Leopold , Megan Currie, Jacob Schwarz, Arnold J. Boersma, Erin D. Sheets, Ahmed A. Heikal 1700-Pos Board B20 CRYTOCHROME AND NUCLEAR RECEPTORS - EXPANDING THE ROLE OF A CANONICAL CIRCADIAN REPRESSOR. Colby Sandate 1701-Pos Board B21 QUO VADIS, BIOMACROMOLECULAR STRUCTURE QUALITY. Radka Svobodova Varekova , Vladimir Horsky, David Sehnal, Veronika Bendova, Lukas Pravda, jaroslav Koca 1702-Pos Board B22 ACETYL-GROUP SENSING THROUGH MODULATION OF CONFORMATION- AL DYNAMICS IN AN ARYLALKYLAMINE N-ACETYLTRANSFERASE. Adam A. Aboalroub , Ashleigh Bachman, Ioannis Gelis 1703-Pos Board B23 INTERDOMAIN CONFORMATIONAL CHANGES IN VISUAL ARRESTIN UPON BINDING TO DIFFERENT FORMS OF RHODOPSIN. Wei-Lin Ou , Ned Van Eps, Takefumi Morizumi, Aidin R. Balo, Oliver P. Ernst 1704-Pos Board B24 EFFECTS OF G ΑI MYRISTOYLATION ON RIC-8A GEF ACTIVITY. Levi J. McClelland , Stephen R. Sprang 1705-Pos Board B25 USING SINGLE MOLECULE FRET TO EXAMINE THE IMPACT OF ENZYMATIC DEGLYCOSYLATION ON THE STRUCTURE OF IMMUNOGLOBULIN G ANTI- BODIES. Alan J. Mlotkowski , Brandon Roman, Mark S. Piraino, Cathrine A. Southern 1706-Pos Board B26 MONITORING MACROMOLECULAR CROWDING VIA FRET USING WAVE- LENGTH-DEPENDENT FLUORESCENCE LIFETIME MEASUREMENTS.  Jacob Schwarz , Megan Currie, Hannah Leopold, Arnold J. Boersma, Ahmed A. Heikal, Erin D. Sheets

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