Biophysical Society 61st Annual Meeting | Program Guide

2360-Plat 2:30 pm FLEXIBILITY DICTATES FUNCTION IN AN EXCEPTIONAL CURVATURE SENS- ING HELIX.  Erin R. Tyndall , Edward Kim, Kumaran S. Ramamurthi, Fang Tian 2361-Plat 2:45 pm RHODOPSIN DIMERIZATION IN MEMBRANE BILAYERS REVEALED BY SMALL ANGLE NEUTRON SCATTERING.  Olivier Soubias , Jonathan D. Nickels, Walter E. Teague, Kirk G. Hines, Kevin L. Weiss, John Katsaras, Klaus Gawrisch Platform Intrinsically Disordered Proteins (IDP) and Aggregates II 1:00 pm - 3:00 pm, Room R06/07 Co-Chairs SINGLE-MOLECULE SPECTROSCOPY REVEALS THE ROLE OF TWO-DI- MENSIONAL CROWDING IN DISORDERED PROTEIN FOLDING.  Priya R. Banerjee , Mahdi Moosa, Ashok Deniz 2363-Plat 1:15 pm International Travel Awardee A TALE OF TWO AMYLOIDOGENIC INTRINSICALLY DISORDERED PRO- TEINS: INTERPLAY OF TAU AND Α-SYNUCLEIN.  Karishma Bhasne , Sanjana Sebastian, Samrat Mukhopadhyay 2364-Plat 1:30 pm TARDIGRADE DISORDERED PROTEINS MEDIATE DESICCATION TOLER- ANCE.  Thomas C. Boothby , Samantha Piszkiewicz, Aakash Mehta, Alex- andra Brozena, Hugo Tapia, Doug Koshland, Alex Holehouse, Rohit Pappu, Bob Goldstein, Gary Pielak 2365-Plat 1:45 pm CONTROLLING THE BIOPHYSICAL PROPERTIES AND FUNCTIONALITY OF PHASE-SEPARATED ELASTIN-BASED DROPLETS THROUGH AMINO ACID SEQUENCE MUTATIONS.  Lisa D. Muiznieks , Fred W. Keeley, Régis Pomès 2366-Plat 2:00 pm Education Travel Awardee MODELING THE EARLY STAGES OF AGGREGATION IN DISORDERED ELASTIN-LIKE PROTEINS.  Yue Zhang , Valeria Zai-Rose, Cody J. Price, Gene L. Bidwell III, John J. Correia, Nicholas C. Fitzkee 2367-Plat 2:15 pm WHAT ENCODES COUPLED FOLDING AND BINDING REACTIONS: IDPS OR PARTNER PROTEINS? Michael D. Crabtree , Carolina A. T. F. Mendonca, Quenton Bubb, Sarah L. Shammas, Jane Clarke 2368-Plat 2:30 pm THE MEASLES VIRUS PHOSPHOPROTEIN: AN INTRINSICALLY DISORDERED CHAPERONE THAT REGULATES NUCLEOCAPSID ASSEMBLY.  Sigrid Milles , Malene Ringkjøbing Jensen, Guillaume Communie, Damien Maurin, Guy Schoehn, Rob WH Ruigrok, Martin Blackledge 2369-Plat 2:45 pm RAMACHANDRAN MAP ANALYSIS OF THE MONOMERIC AB1-40 AND AB1-42 PEPTIDES BY SOLUTION NMR.  Julien Roche Lisa Muiznieks, The Hospital For Sick Children, Canada Sigrid Milles, Institut de Biologie Structurale, France 2362-Plat 1:00 pm

2348-Plat 1:30 pm SINGLE MOLECULE KINETIC MEASUREMENTS AND HIDDEN MARKOV MODELS FOR P2X1 RECEPTORS.  James A. Brozik , Adam O. Barden, Ash- ish Bhattari, Brian N. Webb, Andrew J. Thompson 2349-Plat 1:45 pm STRUCTURAL BASIS AND MOLECULAR MECHANISM UNDERLYING P2X7 RECEPTOR ANTAGONISM.  Akira Karasawa , Toshimitsu Kawate 2350-Plat 2:00 pm BLUE NATIVE PAGE EVIDENCE THAT PLASMA MEMBRANE-BOUND HU- MAN ENAC CHANNELS SHARE A TRIMERIC ARCHITECTURE WITH FULL- LENGTH HUMAN ASIC1 AND ASIC2.  Anke Dopychai , Ralf Hausmann, Linda Krüger, Stefan Gründer, Günther Schmalzing 2351-Plat 2:15 pm MAPPING THE FLEXIBILITY OF AMPA TYPE IONOTROPIC GLUTAMATE RECEPTORS.  Jelena Baranovic , Andrew JR Plested 2352-Plat 2:30 pm PROBING A MOLECULAR LOCK IN A PRIMITIVE NMDA RECEPTOR.  Alvin Yu , Robert Alberstein, Alecia Thomas, Richard Grey, Mark L. Mayer, Albert Lau 2353-Plat 2:45 pm INVESTIGATING THE SCRAMBLING MECHANISM OF TMEM16 SCRAMBLA- SES. Mattia Malvezzi , Rabia Iqbal, Ashley Brown, Anant Menon, Alessio Accardi Platforms Protein-Lipid Interactions: Structures 1:00 pm - 3:00 pm, Room R04/05 Co-Chairs Steven R. Van Doren, University of Missouri Olivier Soubias, NIH 2354-Plat 1:00 pm TRANSIENT INTERACTIONS OF METALLOPROTEINASES WITH BILAY- ERS, CAPTURED BY PARAMAGNETIC NMR, INCLUDE DUAL MODES OF BINDING, ELECTROSTATIC RECRUITING, AND ALLOSTERY.  Steven R. Van Doren , Stephen H. Prior, Yan G. Fulcher, Jia Xu, Tara C. Marcink, Rama K. 1:15 pm OXIDIZED LIPIDS: THEIR ROLE IN REGULATION OF MITOCHONDRIAL APOPTOSIS.  Artur Dingeldein, Jörgen Aden, Tobias Sparrman, Radek Sachl, Sarka Pokorna, Martin Hof, Gerhard Gröbner 2356-Plat 1:30 pm SPECTROSCOPIC INVESTIGATION OF Α-SYNUCLEIN 71-82, A PEPTIDE DE- RIVED FROM A PROTEIN INVOLVED IN PARKINSON’S DISEASE.  Benjamin Martial , Émilie Bruneau, Laurie Bédard, Thierry Lefèvre, Michèle Auger 2357-Plat 1:45 pm DETERMINANTS OF LIPID SPECIFICITY FOR THE FVII MEMBRANE BINDING DOMAIN. Melanie Muller , Emad Tajkhorshid 2358-Plat 2:00 pm STRUCTURE OF THE SAR1 LATTICE AND ITS ROLE IN COPII VESICLE FOR- MATION AND SCISSION.  Peter Randolph , Hanaa Hariri, Scott Stagg 2359-Plat 2:15 pm ROLE OF PIP2-DEPENDENT MEMBRANE INTERACTIONS IN VINCULIN ACTIVATION, MOTILITY AND FORCE TRANSMISSION.  Sharon L. Campbell , Peter M. Thompson, Srinivas Ramachandran, Lindsay Case, Nikolay Dokholyan, Caitlin Tolbert, Clare M. Waterman Koppisetti 2355-Plat

W E

D N

E S

D A Y

130