Biophysical Society 61st Annual Meeting | Program Guide

Protein Structure and Conformation IV (Boards B1–B15) 2394-Pos Board B1 DEVELOPMENT AND COMPARISON OF ENHANCED SAMPLING METH- ODS FOR BIOMOLECULAR SIMULATION.  James Lincoff , Sukanya Sasmal, Teresa Head-Gordon 2395-Pos Board B2 STRUCTURAL CHARACTERISTICS OF THE RNASE H DOMAIN IN HIV-1 REVERSE TRANSCRIPTASE. Ryan L. Slack , Naima G. Sharaf, Angela M. Gronenborn, Rieko Ishima 2396-Pos Board B3 EFFECTS OF ALS MUTATIONS ON STRUCTURE, DYNAMICS, AND FUNC- TION OF UBIQUILIN-2. Carlos A. Castaneda , Thuy P. Dao 2397-Pos Board B4 ENERGY LANDSCAPES OF A MECHANICAL PRION AND THEIR IMPLICA- TIONS FOR THE MOLECULAR MECHANISMS OF LONG-TERMMEMO- RY. Mingchen Chen 2398-Pos Board B5 METHYL-LABELING ASSISTED NMR STRUCTURE DETERMINATION OF A 66 KDA GROWTH FACTOR-RECEPTOR COMPLEX. Andrew Hinck , Morkos A. Henen, Christian Zwieb, Ravindra Kodali, Cynthia S. Hinck 2399-Pos Board B6 SOLUTION NMR STRUCTURES OF THE C-TERMINAL DOMAIN OF TET- RAHYMENA CYTOSKELETAL PROTEIN TCB2 REVEAL DISTINCT CALCIUM- INDUCED STRUCTURAL REARRANGEMENTS. Adina M. Kilpatrick , Jerry E. Honts, Heidi M. Sleister, C. Andrew Fowler 2400-Pos Board B7 UNDERSTANDING EFFECT OF GERANYLATION OF TRNA LYS ON RIBOSOME BINDING: A COMPUTATIONAL STUDY. Sweta Vangaveti , Phensinee Har- uehanroengra, Rui Wang, Srivathsan V. Ranganathan, Jia Sheng 2401-Pos Board B8 NANO-MECHANICAL STUDIES OF COLLAGEN: THE INFLUENCE OF IONIC STRENGTH, PH AND COLLAGEN SOURCES ON MOLECULAR FLEXIBIL- ITY. Naghmeh Rezaei , Aaron Lyons, Nancy R. Forde 2402-Pos Board B9 STRUCTURAL CHARACTERIZATION OF CWSA IN A LIPID BILAYER WITH SSNMR. Rongfu Zhang 2403-Pos Board B10 DETERMINATION OF THE SOLUTION STRUCTURE OF ISOLATED HISTONE H2A-H2B HETERODIMER BY USING CS-ROSETTA. Tsutomu Yamane , Yoshihito Moriwaki, Hideaki Ohtomo, Mitsunori Ikeguchi, Mitsunori Ike- guchi, Jun-ichi Kurita, Masahiko Sato, Aritaka Nagadoi, Hideaki Shimojo, Yoshifumi Nishimura 2404-Pos Board B11 QUANTITATIVE NMR ANALYSIS OF CONCURRENT PHOSPHORYLATION EVENTS AND PHOSPHORYLATION-RELATED STRUCTURAL CHANGES IN UNSTRUCTURED CYTOPLASMIC DOMAIN OF T-CELL RECEPTOR CD3Γ SUBUNIT.  Innokentiy Maslennikov , Christian Klammt, Johan Kufs, Amy Blount, Barbara Varsonofieva, Bjoern Lillemeier 2405-Pos Board B12 DIFFERENT APPLICATIONS FOR CAS IN FUNCTIONAL CLASSIFICATION OF PROTEIN INTERFACES. Cameron J. Jones , Sanjana Sudarshan, Isha D. Mehta, Brian W. Beck 2406-Pos Board B13 FUSION PROTEIN, DNAJB1-PRKACA, AS A CANCER DRIVER. Tsan-Wen Lu , Michael Cianfrocco, Ping Zhang, Susan Taylor

2407-Pos Board B14 EFFECT OF PHOSPHORYLATION ON SUPERTERTIARY STRUCTURE AND LIGAND BINDING AFFINITY ON SCAFFOLD PROTEINS. Brié N. Levesque , Fang Wu, Mark E. Bowen 2408-Pos Board B15 TOXIC METAL IONS PROMOTE SELF-ASSOCIATION AND REPLACE STRUC- TURAL ZINC IONS IN THE REGULATORY REGION OF PROTEIN KINASE C. Taylor R. Cole , Samuel G. Erickson, Min Woo Sung, Andreas Holzen- burg, Tatyana I. Igumenova Aggregates, Chaperones, and Mechanical Forces (Boards B16–B30) 2409-Pos Board B16 USING SINGLE MOLECULE CHEMO-MECHANICAL UNFOLDING TO PROBE THE EFFECT OF ENVIRONMENTAL CONDITIONS ON PROTEIN FOLD- ING. Emily J. Guinn , Bharat Jagannathan, Susan Marqusee 2410-Pos Board B17 PROTEIN AGING: LOSS OF FOLDING CONTRACTION DUE TO OXIDATION OF CRYPTIC SIDE CHAINS.  Jessica Valle Orero , Jaime Andres Rivas-Pardo, Rafael Tapia-Rojo, Ionel Popa, Daniel J. Echelman, Julio M. Fernandez 2411-Pos Board B18 THERMODYNAMICS AND KINETICS OF GLOBULAR POLYMERS UNDER AN APPLIED FORCE. Samuel Bell , Eugene M. Terentjev 2412-Pos Board B19 MECHANO-INDUCED UNFOLDING OF VON WILLEBRAND FACTOR: A CLINICAL EXAMPLE OF PROTEIN DESTABILIZATION. Camilo A. Aponte Santamaria , Svenja Lippok, Judith J. Mittag, Tobias Obser, Reinhard Schneppenheim, Carsten Baldauf, Frauke Gräter, Ulrich Budde, Joachim Rädler 2413-Pos Board B20 MECHANICAL ARCHITECTURE AND GENESIS OF BACTERIAL PILUS DO- MAINS REVEALED BY SINGLE-MOLECULE FORCE SPECTROSCOPY. Alvaro Alonso-Caballero, Raul Perez-Jimenez 2414-Pos Board B21 MULTISCALE MODELING OF PROTEIN UNFOLDING AND TRANSLOCATION BY AAA+ CHAPERONES IN THE DEGRADATION PATHWAY. Andrea N. Kra- vats, Sam Tonddast-Navaei, Abdolreza Javidialesaadi, George Stan 2415-Pos Board B22 Education Travel Awardee EVIDENCE FOR CHAPERONE FUNCTION IN MECHANOSENSATION.  Miranda Collier , Georg Hochberg, Cameron Turtle, Carin De Villiers, Katja Gehmlich, Justin L.P. Benesch 2416-Pos Board B23 Education Travel Awardee PROMISCUOUS HISTONE MIS-ASSEMBLY IS ACTIVELY PREVENTED BY CHAPERONES. Haiqing Zhao 2417-Pos Board B24 PROTEIN KINASE RECOGNITION AND SORTING BY THE HSP90 KINOME- SPECIFIC COCHAPERONE CDC37.  Ioannis Gelis , Dimitra Keramisanou, Adam Aboalroub 2418-Pos Board B25 TRACKING STRUCTURAL CHANGES IN THE UCS DOMAIN OF THE MYOSIN CHAPERONE UNC-45 BY FLUORESCENCE SPECTROSCOPY. Andres Oberhauser , Paul Nicholls 2419-Pos Board B26 UNFOLDING EFFICACY OF THE IMMUNOGLOBULIN DOMAIN I27 CON- TROLLED BY FORCE DIRECTIONALITY IN PROTEIN REMODELING BY CLP ATPASE CHAPERONES. Abdolreza Javidialesaadi , George Stan

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