Biophysical Society 61st Annual Meeting | Program Guide

2512-Pos Board B119 DESIGN OF SUPERCHARGED PROTEINS TO IMPART ALLOSTERIC BEHAV- IOR AND THEIR USE IN BIOSENSING. Peter Schnatz , Joseph Brisendine, Derek Kosciolek, David Crouse, Ronald Koder 2513-Pos Board B120 LIKE CHARGE REGIONS (LCRS) ARE ONE OF THE KEY REGULATORS OF NUCLEOCYTOPLASMIC TRANSPORT. Mohaddeseh Peyro , Mohammad Soheilypour, Mohammad R. K. Mofrad 2514-Pos Board B121 THE INTRINSICALLY DISORDERED TAIL OF FTSZ IMPACTS POLYMERIZATION AND BACTERIAL CELL DIVISION THROUGH SEQUENCE-ENCODED CHARGE PATTERNING. Megan C. Cohan , Ammon Posey, Steven Grigsby, Alex S. Holehouse, Anuradha Mittal, Paul J. Buske, Petra Levin, Rohit V. Pappu 2515-Pos Board B122 DISSECTING CONFORMATIONAL FEATURES AND BINDING MECHANISMS OF PHENYLALANINE-GLYCINE RICH NUCLEOPORINS. Piau Siong Tan , Iker Valle Aramburu, Swati Tyagi, Aritra Chowdhury, Edward A. Lemke 2516-Pos Board B123 POLYGLUTAMINE LENGTH DEPENDENT STRUCTURAL PROPERTIES AND PHASE BEHAVIOR OF HUNTINGTIN EXON 1. Kiersten M. Ruff , John B. Warner, Ammon E. Posey, Piau Siong Tan, Edward A. Lemke, Rohit V. Pappu, Hilal A. Lashuel 2517-Pos Board B124 MOLECULAR DYNAMICS STUDY OF EARLY STAGE KINETICS OF POLYGLU- TAMINE AGGREGATION.  Jason Haaga , C. Nadia Buckles, James D. Gunton 2518-Pos Board B125 CROWDING INDUCED COIL-GLOBULE TRANSITIONS OF INTRINSICALLY DISORDERED PROTEINS. Youngchan Kim , Jeetain Mittal 2519-Pos Board B126 THERMODYNAMIC PROPERTIES OF SYNB1-CYS-ELP-DRUG CARRIER AND THE ROLE OF OSMOLYTES. Valeria Zai-Rose , John J. Correia 2520-Pos Board B127 Education Travel Awardee TARDIGRADE INTRINSICALLY DISORDERED PROTEINS AS POTENTIAL EX- CIPIENTS FOR BIOLOGICS. Samantha Piszkiewicz , Aakash Mehta, Thomas C. Boothby, William Daniel, Sergei Sheiko, Bob Goldstein, Gary J. Pielak 2521-Pos Board B128 EXPLORING THE UNEXPECTED GELATION OF TRIPEPTIDES IN A BINARY MIXTURE OF WATER AND ETHANOL. David DiGuiseppi , Stefanie Farrell, Nicolas Alvarez, Reinhard Schweitzer-Stenner 2522-Pos Board B129 EXPLORING THE EFFECTS ON THE CONFORMATIONAL PROPENSITY OF ALANINE IN THE UNBLOCKED TRIPEPTIDE GLYCYL-ANALYL-GLYCINE IN WATER/ETHANOL MIXTURES. David DiGuiseppi , Nina Kubatova, Gabrielle Lewis, Harald Schwalbe, Reinhard Schweitzer-Stenner DNA Replication, Recombination, and Repair (Boards B130–B147) 2523-Pos Board B130 NEAR-ATOMIC STRUCTURAL MODEL FOR BACTERIAL DNA REPLICATION INITIATION COMPLEX AND ITS FUNCTIONAL INSIGHTS. Masahiro Shimizu , Yasunori Noguchi, Yukari Sakiyama, Hironori Kawakami, Tsutomu Katayama, Shoji Takada 2524-Pos Board B131 UPF1-LIKE HELICAES - SAME SUBFAMILY, YET SO DIFFERENT BEHAV- IOR. Saurabh Raj, Joanne Kanaan, Hervé Le Hir, Vincent Croquette

2500-Pos Board B107 ENERGY LANDSCAPE MODEL AND SPATIAL MOTION MODELS IN RHODOPSIN ACTIVATION. Suchithranga M.D.C. Perera , Udeep Chawla, Andrey V. Struts, Michael F. Brown 2501-Pos Board B108 ACTIVATION OF GPCR RHODOPSIN INVESTIGATED BY SOLID-STATE NMR SPECTROSCOPY. Andrey V. Struts , Xiaolin Xu, Trivikram R. Molugu, Mike C. Pitman, Samira Faylough, Charitha Guruge, Carolina L. Nascimento, Nasri Nesnas, Michael F. Brown 2502-Pos Board B109 MANIPULATING THE DIMERIC INTERFACE OF HUMAN CONE OPSINS.  William D. Comar 2503-Pos Board B110 INVESTIGATING THE GATING MECHANISM OF G PROTEIN-ACTIVATED INWARD RECTIFYING POTASSIUM CHANNELS. Harald Bernsteiner , Anna Stary-Weinzinger 2504-Pos Board B111 SINGLE PROTEIN TRACKING OF P450-REDUCTASE IN AN ENDOPLASMIC RETICULUM BIOMIMETIC REVEALS A NADPH DEPENDENT INTERACTION WITH THE MEMBRANE.  James A. Brozik , Carlo Barnaba, Adam O. Barden, Linda Agyen, Sean L. Sheridan 2505-Pos Board B112 Education Travel Awardee A EUKARYOTIC SENSOR FOR MEMBRANE LIPID SATURATION. Roberto Covino , Stephanie Ballweg, Claudius Stordeur, Jonas B. Michaelis, Kristina Puth, Florian Wernig, Amir Bahrami, Andreas M. Ernst, Gerhard Hummer, Robert Ernst 2506-Pos Board B113 ANALYSIS OF THE DYNAMICS OF A MULTI-DRUG EXPORTER ACRB IN THE ABSENCE AND PRESENCE OF SUBSTRATES. Tomoki Matsuda , Seiji Yama- saki, Kunihiko Nishino, Takeharu Nagai, Akihito Yamaguchi 2507-Pos Board B114 PREPARATION OF NICOTINIC ACETYLCHOLINE RECEPTOR DETERGENT COMPLEXES FOR STRUCTURAL STUDIES: ASSESSMENT OF PURITY, FUNC- TIONALITY AND AGGREGATION ANALYSIS. Bianca N. Valdés Fernández , Hui Wei, Luis López Cruz, Francis Reilly Andujar, Rafael Cordero Villamil, Bryan Cobo Torres, Orlando Gonzalez Martinez, Jose A. Lasalde Dominicci Intrinsically Disordered Proteins (IDP) and Aggregates III (Boards B115–B129) 2508-Pos Board B115 MULTIPLY-PHOSPHORYLATED INTRINSICALLY DISORDERED SIGNALING MOLECULES CAN EXHIBIT EMERGENT COOPERATIVITY AND SEQUENTIAL BINDING. Lara Clemens , Omer Dushek, Jun Allard Board B116 PHOSPHORYLATION INDUCES SEQUENCE-SPECIFIC CONFORMATIONAL SWITCHES IN THE RNA POLYMERASE II C-TERMINAL DOMAIN. Scott A. Showalter , Eric B. Gibbs 2510-Pos Board B117 Education Travel Awardee INTERPLAY AMONG BINDING, PHOSPHORYLATION AND DENATURATION IN DISORDERED 4E-BP2 AS PROBED BY SINGLE MOLECULE FLUORES- CENCE. Zhenfu Zhang , Alaji Bah, Julie D. Forman-Kay, Claudiu C. Gradi- naru 2511-Pos Board B118 SEQUENCE DETERMINANTS OF THE CONFORMATIONAL PROPERTIES OF AN INTRINSICALLY DISORDERED PROTEIN PRIOR TO AND UPON MUL- TISITE PHOSPHORYLATION. Erik W. Martin , Alex S. Holehouse, Rohit V. Pappu, Tanja Mittag 2509-Pos

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