Biophysical Society 61st Annual Meeting | Program Guide

2724-Pos Board B331 BARBITURATES BIND IN THE GLIC ION CHANNEL PORE AND CAUSE INHIBITION BY STABILIZING A SHUT STATE. Zeineb Fourati, Reinis R. Ruza, Duncan Laverty, Emmanuelle Drege, Sandrine Delarue-Cochin, Delphine Joseph, Patrice Koehl, Trevor Smart, Marc Delarue 2725-Pos Board B332 THERMOANALYTICAL CHARACTERIZATION OF PENTAMERIC ELIC BASED ON DETERGENT SIZE. Ty E. Whisenant , Benjamin W. Elberson, Doris M. Cortes, Luis G. Cuello 2726-Pos Board B333 BIOCHEMICAL AND THERMODYNAMIC CHARACTERIZATION OF THE ERWINIA CHRYSANTHEMI LIGAND-GATED ION CHANNEL. Benjamin W. Elberson , Ty E. Whisenant, D. Marien Cortes, Luis G. Cuello 2727-Pos Board B334 DECIPHERING ANESTHETIC ACTION OF NOBLE GASES THROUGH THEIR MODULATION OF MEMBRANE PROTEIN AND LIPID BILAYER PROPER- TIES. Samuel Murail , Pluton Pullumbi, Marc Baaden 2728-Pos Board B335 CPOW Travel Awardee TRANSMEMBRANE STRUCTURAL DETERMINANTS OF ALCOHOL BINDING AND MODULATION IN A MODEL LIGAND-GATED ION CHANNEL.  Rebecca J. Howard , Stephanie A. Heusser, Özge Yoluk, Oliver Snow, Göran Klement, Alex R. Mola, Travers MD Ruel, Erik Lindahl 2729-Pos Board B336 KETAMINE INHIBITION OF PENTAMERIC LIGAND-GATED ION CHANNELS - INSIGHTS FROMMOLECULAR DYNAMICS SIMULATIONS. Bogdan F. Ion , Marta M. Wells, Yan Xu, Pei Tang 2730-Pos Board B337 International Travel Awardee STRUCTURAL AND FUNCTIONAL EVIDENCE FOR MULTI-SITE ALLOSTERY MEDIATED BY GENERAL ANESTHETICS IN A MODEL LIGAND-GATED ION CHANNEL. Stephanie A. Heusser , Rebecca J. Howard, Zeineb Fourati, Marc Delarue, Erik Lindahl 2731-Pos Board B338 DETERMINANTS OF 5-HT 3A INTRACELLULAR DOMAIN OLIGOMERIZATION AND RIC-3 INTERACTION. Elham Pirayesh , Akash Pandhare, Michaela Jansen 2732-Pos Board B339 CHARACTERIZING THE INTRINSIC ASSEMBLY BEHAVIOR OF THE 5-HT 3A RECEPTOR INTRACELLULAR DOMAIN. Akash Pandhare , Michaela Jansen 2733-Pos Board B340 DEVELOPMENT OF A PENTAMERIC, NON-CHIMERIC 5-HT 3A RECEPTOR INTRACELLULAR DOMAIN CONSTRUCT. Mina Ahmadi , Akash Pandhare, Michaela Jansen 2734-Pos Board B341 RELATIVE AFFINITIES OF GENERAL ANESTHETICS FOR PSEUDO-SYMMET- RIC INTERSUBUNIT BINDING SITES OF HETEROMERIC GABA(A) RECEP- TORS. Sruthi Murlidaran , Reza Salari, Jerome Hénin, Grace Brannigan 2735-Pos Board B342 INVESTIGATING STRUCTURAL TRANSITIONS OF GABA-A RECEPTORS USING ACCELERATED MOLECULAR DYNAMICS. Ole J. Andersen , Philip C. Biggin 2736-Pos Board B343 Education Travel Awardee STRUCTURAL ELEMENTS GOVERNING GABA-A RECEPTOR CHANNEL AC- TIVATION AND DRUG MODULATION. Tzu-Wei Tsao , Connor Ford, Chong Lor, Robert Pearce, Cynthia Czajkowski 2737-Pos Board B344 BINDING MODES OF FULL AND PARTIAL AGONISTS IN THE ORTHOSTERIC BINDING SITE OF THE GLYCINE RECEPTOR. Marc A. Dämgen , Timo Greiner, Remigijus Lape, Lucia G. Sivilotti, Philip C. Biggin

2710-Pos Board B317 EFFECT OF ELECTROOSMOTIC FLOW ON THE TRANSPORT OF Α-CYCLODEXTRIN THROUGH THE CHANNEL CYMA.  Jigneshkumar Dahyabhai Prajapati , Satya Prathyusha Bhamidimarri, Mathias Winter- halter, Ulrich Kleinekathoefer 2711-Pos Board B318 MOLECULAR DETERMINANTS OF PHOTOCURRENT KINETICS OF THE RED LIGHT ACTIVABLE CHANNELRHODOPSIN CHRIMSON.  Johannes Vierock , Noam Nitzan, Peter Hegemann 2712-Pos Board B319 SEARCHING FOR A POTENTIAL VOLTAGE SENSOR INTRINSIC TO PANNEXIN CHANNELS. Kevin Michalski , Toshi Kawate 2713-Pos Board B320 CHARACTERIZATION OF STRUCTURAL CHANGES VIA LIPID REGULATION OF KIR2.1 IN A LIPID ENVIRONMENT.  Joshua Brettmann , Sunjoo Lee, Shizhen Wang, Colin G. Nichols 2714-Pos Board B321 ELECTROPHYSIOLOGICAL INVESTIGATION OF THE SODIUM PUMP KR2. Christiane Grimm , Arend Vogt, Peter Hegemann 2715-Pos Board B322 VOLTAGE AND TIME DEPENDENCE OF AMPHOTERICIN B CHANNEL ACTIV- ITY IN LIPIDIC MEMBRANES. Karla S. Récamier , Iván Ortega-Blake, Punit Parmananda 2716-Pos Board B323 EFFECTS OF CYTOPLASMIC TAIL TRUNCATIONS ON CONNEXIN 50 HEMI- CHANNEL FUNCTION.  Justine J. Jacobi , Derek L. Beahm 2717-Pos Board B324 COMPARISON OF SECOND MESSENGER PERMEABILITIES THROUGH GAP JUNCTION CHANNELS FORMED BY CX43 AND CX50. Virgis Valiunas , Laima Valiuniene, Peter R. Brink, Thomas W. White 2718-Pos Board B325 INVESTIGATION OF SIDEROPHORE-MONOBACTAM ANTIBIOTIC DERIVA- TIVES: THEIR IRON(III)-COMPLEXES AND BINDING TO RECEPTORS. Mari- ano A. Scorciapino , Giuliano Malloci, Matteo Ceccarelli, Lucile Moynie, James H. Naismith, Eric Desarbre, Malcolm Page 2719-Pos Board B326 TMEM16A MEDIATES THE FAST BLOCK TO POLYSPERMY IN XENOPUS LAE- VIS EGGS. Katherine L. Wozniak, Brianna L. Mayfield, Anne E. Carlson Ligand-gated Channels II (Boards B327–B345) 2720-Pos Board B327 FUNCTIONAL CHARACTERIZATION OF A NICOTINIC ACETYLCHOLINE RECEPTOR FROM AN EXTREMOPHILE WORM. Eveline Wijckmans, Florian Delbart, Chris Ulens 2721-Pos Board B328 ACETYLCHOLINE RECEPTOR GATING: CLICK-TWIST-TILT-RIP-POP. Shaweta Gupta, Srirupa Chakraborty , Ridhima Vij, Tapan K. Nayak, Anthony Board B329 A FLUORESCENT AGONIST OF THE MUSCLE NICOTINIC ACETYLCHOLINE RECEPTOR. Abhilasha Ladha , Vera Martos, Andrew Plested, Jana Kusch 2723-Pos Board B330 THE INTRACELLULAR DOMAIN OF PENTAMERIC LIGAND-GATED ION CHANNELS AND ITS EFFECT ON RECEPTOR CONDUCTANCE IN GLIC CHI- MERAS. Antonia Stuebler , Pablo Artigas, Michaela Jansen Auerbach 2722-Pos

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