Biophysical Society 61st Annual Meeting | Program Guide

Protein Structure and Conformation I (Boards B1–B28) 236-Pos Board B1 A DISCRETE LOOP OF THE SERCA N-DOMAIN INTERACTS WITH PHOS- PHOLAMBAN AND STABILIZES A COMPACT CONFORMATION OF THE SERCA CYTOSOLIC HEADPIECE. Olga N. Raguimova , Nikolai Smolin, Daniel Blackwell, Elisa Bovo, Aleksey Zima, Seth Robia 237-Pos Board B2 PREPARATION OF A OREXIN PRECURSOR PROTEIN BY CHEMICAL DIGES- TION. Natsumi Mitsuoka , Shigeru Shimamoto, Yuji Hidaka 238-Pos Board B3 A SIMULATION BASED ANALYSIS OF THE OLIGOMERIC PLASTICITY OF SM PROTEIN ASSEMBLIES. Charles E. McAnany , Berk Ekmekci, Peter Randolph, Cameron Mura 239-Pos Board B4 NANOMECHANICAL PROPERTIES OF POLYMORPHIC HUMAN ISLET AMY- LOID POLYPEPTIDE PROTOFIBRILS IN THE MULTIPLE PHYSIOLOGICAL AND MECHANICAL CONDITIONS. Myeongsang Lee 241-Pos Board B6 PROTEIN STRUCTURE DETERMINATION BY HIGH-PRECISION FRET AND MOLECULAR MODELING. Mykola Dimura , Thomas Peulen, Holger Gohlke, Claus A. M. Seidel 242-Pos Board B7 APO- AND ANTAGONIST-BINDING STRUCTURES OF VITAMIN D RECEPTOR LIGAND-BINDING DOMAIN REVEALED BY A COMBINATION ANDLYSIS OF MD SIMULATIONS AND SAXS EXPERIMENTS. Yasuaki Anami, Nobutaka Shimizu, Toru Ekimoto , Daichi Egawa, Toshimasa Itoh, Mitsunori Ikeguchi, Keiko Yamamoto 243-Pos Board B8 CONFORMATIONAL FLUCTUATIONS AS AN INTRINSIC MECHANISM OF ACTION: THE LIPASE-SPECIFIC FOLDASE OF PSEUDOMONAS AERUGINOSA STUDIED BY HYBRID FLUORESCENCE SPECTROSCOPY AND MD SIMULA- TIONS.  Jakub Kubiak , Neha Verma, Peter Dollinger, Filip Kovacic, Karl- Erich Jaeger, Holger Gohlke, Claus A.M. Seidel 244-Pos Board B9 DOES CAS9-CATALYZED DNA CLEAVAGE GENERATE BLUNT ENDS OR STAGGERED ENDS? INSIGHT FROMMOLECULAR DYNAMIC SIMULA- TIONS. Zhicheng Z. Zuo , Jin Liu 245-Pos Board B10 METHIONINE SULFOXIDE FORMATION BY CIGARETTE SMOKE IS ASSOCI- ATED WITH THE DEGRADATION OF PLASMA PROTEINS. Abdullah Qassab , Rohana Liyanage, Wesley Stites 246-Pos Board B11 DYNAMICS AND ENERGETICS OF ELONGATION FACTOR SELB IN THE TER- NARY COMPLEX AND THE RIBOSOME. Lars V. Bock , Niels Fischer, Holger Stark, Holger Stark, Helmut Grubmüller 247-Pos Board B12 POLYETHYLENE GLYCOL CONJUGATION ENHANCES MOSQUITO-LARVICI- DAL ACTIVITY OF LYSINIBACILLUS SPHAERICUS BINA PROTEIN. Mahima Sharma , Ramesh S. Hire, Ashok B. Hadapad, Gagan Deep Gupta, Vinay Kumar 248-Pos Board B13 A NOVEL ELECTROSTATIC REGULATORY MECHANISM IN A CALCIUM BINDING PROTEIN, L-PLASTIN. Jonn Keenan Fanning, Van A. Ngo , Hiroaki Ishida, Hans Vogel, Sergei Yu. Noskov AN NMR STUDY OF PIN1- HISTONE H1 INTERACTIONS.  Dinusha S. Jinasena , Hawa Gyamfi, Nicholas C. Fitzkee 240-Pos Board B5

249-Pos Board B14 STRUCTURAL DESTABILIZATION OF TROPOMYOSIN INDUCED BY A CARDIOMYOPATHY-LINKED MUTATION. Thu N. Ly , Inna Krieger, Young-Ho Yoon, Dmitri Tolkatchev, Fadel A. Samatey, Alla S. Kostyukova 250-Pos Board B15 PROBING CONFORMATIONAL AND FUNCTIONAL SUBSTATES OF CALMODULIN BY HIGH-PRESSURE FTIR. Nelli Erwin , Satyajit Patra, Roland Winter 251-Pos Board B16 0BSCURIN ACTS AS A VARIABLE FORCE RESISTOR. Nathan T. Wright , Aidan M. Willey 252-Pos Board B17 STRUCTURAL AND FUNCTIONAL INSIGHT INTO RECOMBINANT LUNG SURFACTANT PROTEIN B (RSP-B). Tadiwos G. Asrat , Valerie Booth 253-Pos Board B18 REGULATION OF FOLDING OF DE NOVO DESIGNED PEPTIDES BY Α-HELIX FORMATION. Saya Nishihara , Kosuke Toyama, Shigeru Shimamoto, Yuji Hidaka 254-Pos Board B19 CHARACTERIZATION OF PROTEIN KINASE A FREE ENERGY LANDSCAPE BY NMR-RESTRAINED METADYNAMICS. Yingjie Wang , Carlo Camilloni, Jong- gul Kim, Michele Vendruscolo, Jiali Gao, Gianluigi Veglia 255-Pos Board B20 THERMAL RESPONSE OF INNER AND OUTER TRANSMEMBRANE SEG- MENTS OF CORA PROTEIN BY A COARSE-GRAIN MONTE CARLO SIMULA- TION. Ras Pandey , Sunan Kitjaruwankul, Channarong Khrutto, Pornthep Sompornpisut, Barry Farmer 256-Pos Board B21 THE COMPETITION BETWEEN ELECTROSTATIC-STEERING AND CONFOR- MATIONAL DYNAMICS IN THE DIFFUSION-LIMITED ASSOCIATION OF CALCINEURIN AND CALMODULIN. Peter M. Kekenes-Huskey , Bin Sun, Eric C. Cook, Trevor P. Creamer 257-Pos Board B22 EQUILIBRIUMMOLECULAR DYNAMICS OF THE MONOMER AND DIMER UNITS OF STREPTOCOCCUS PNUEMONAE AND CORYNEBACTERIUM DIPHTHERIAE PILI. Emmanuel Naziga , Jeff Wereszczynski 258-Pos Board B23 BIOPHYSICAL AND STRUCTURAL CHARACTERIZATION OF ANTIBODY RESPONSES TO MALARIA ANTIGENS. Stephen Scally, Alexander Bosch, Brandon McLeod, Gianna Triller, Katharina Imkeller, Rajagopal Murugan, Sebastian Rämisch, Rick King, William Schief, Hedda Wardemann, Jean- Philippe Julien 259-Pos Board B24 STRUCTURAL ANALYSIS OF THE PRECURSOR PROTEIN OF ATRIAL NATRI- URETIC PEPTIDE. Sumika Futori , Satomi Higashigawa, Shigeru Shima- moto, Yuji Hidaka 260-Pos Board B25 INHIBITION OF AGGREGATION IN B-SHEET MODEL PEPTIDE BY PPII HELIX CAPPING. Heng Chi , Min Zhou, Timothy A. Keiderling 261-Pos Board B26 PROTEIN FOLDING AS A RESONANCE PHENOMENON, WITH FOLDING FREE ENERGIES DETERMINED BY PROTEIN-HYDRATION SHELL INTERAC- TIONS. Sungchul Ji 262-Pos Board B27 RECONSTRUCTION OF PRIMORDIAL PLOOP NTPASE PRECURSORS. Maria Luisa Romero-Romero

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