Biophysical Society 61st Annual Meeting | Program Guide

275-Pos Board B40 POLARIZABLE AMOEBA FORCE FIELD METADYNAMICS WITH MINIMI- ZATION PREDICTS MISSING PROTEIN LOOPS. Armin Avdic, Mallory R. Tollefson, Nicole Tatro, Stephen D. LuCore, Jacob M. Litman, Timothy D. Fenn, Michael J. Schnieders 276-Pos Board B41 IMPROVING 3D STRUCTURE PREDICTION OF BETA-BARREL MEMBRANE PROTEINS. Wei Tian , Hammad Naveed, Jie Liang 277-Pos Board B42 DE NOVO PROTEIN STRUCTURE PREDICTION BY BIG DATA AND DEEP LEARNING. Sheng Wang, Jinbo Xu 278-Pos Board B43 NEXT GENERATION EVOLUTIONARY SAMPLING AND ENERGY FUNCTION GUIDED AB INITIO PROTEIN STRUCTURE PREDICTION. Avdesh Mishra , Md Tamjidul Hoque 279-Pos Board B44 A PREDICTED STRUCTURE OF THE ANGIOMOTIN LIPID BINDING DO- MAIN. Ann C. Kimble-Hill , Cameron J. Peck, Piiamaria S. Virtanen 280-Pos Board B45 SELF-ASSOCIATION AND CONFORMATIONAL STABILITY OF NAMPT PRO- TEIN. Trivikram R. Molugu , Udeep Chawla, Annie Huang, Radu C. Oita, Ting Wang, Michael F. Brown, Joe G. N. Garcia 281-Pos Board B46 THE INTERVAL BRANCH-AND-PRUNE ALGORITHM FOR THE PROTEIN STRUCTURE DETERMINATION. Thérèse E. Malliavin , Bradley Worley, Ben- jamin Bardiaux, Guillaume Bouvier, Mohamed Machat, Andrea Cassioli, Carlile Lavor, Leo Liberti, Michael Nilges  Protein Stability (Boards B47–B63) 282-Pos Board B47 BIOLOGICAL ROLES OF PROTEIN HYPERSTABILITY: IMPLICATIONS FOR BIOTECHNOLOGY. Wilfredo Colón , Ke Xia, Jennifer Church, Jayeeta Sen, Jane Thibeault, Hannah S. Trasatti 283-Pos Board B48 VOLUMETRICALLY DERIVED THERMODYNAMIC PROFILE OF INTERAC- TIONS OF UREA WITH A NATIVE PROTEIN.  Ikbae Son , Tigran Chalikian 284-Pos Board B49 SUB-STATE CONFORMATIONS OF THE MESOPHILIC AND PSYCHROPHILIC LACTATE DEHYDROGENASES PRECEDING IRREVERSIBLE THERMAL INACTI- VATION. Sergei Khrapunov , Eric Chang, Robert Callender 285-Pos Board B50 DENATURED STATE LOOP FORMATION THERMODYNAMICS OF A HYBRID POLYPEPTIDE. Moses Leavens , Bruce E. Bowler 286-Pos Board B51 REGULATION OF PROTEIN FOLDING USING ORGANIC SOLVENTS AND IONIC LIQUIDS. Yuji Hidaka , Ryosuke Nishimura, Shigeru Shimamoto 287-Pos Board B52 GLYCINE BETAINE REVERSES OSMOTIC SHOCK INDUCED PROTEIN DESTA- BILIZATION IN LIVING CELLS. Samantha S. Stadmiller , Gary J. Pielak 288-Pos Board B53 FLUORESCENCE EVIDENCES FOR NON-HOMOGENEITY AND RESIDUAL STRUCTURE OF DENATURED STATES. Katherina Hemmen , Dmitro Rodnin, Igor Markovic, Thomas Otavio Peulen, Suren Felekyan, Ralf Kuehnemuth, Hugo Sanabria, Claus A M Seidel

263-Pos Board B28 PROBING PROTEIN FOLDING AND INTERACTION IN LIVE CELLS USING OSMOTIC PERTURBATIONS. Shahar Sukenik , Martin Gruebele Protein Structure, Prediction, and Design I (Boards B29–B46) 264-Pos Board B29 UNDERSTANDING THE ROLE OF CHAIN FLEXIBILITY IN AMYLOID PROTEIN AGGREGATION THROUGH RATIONALLY DESIGNED PROTEIN SEQUENC- ES. Steven Z. Vance , Xavier Redmon, Rachel Hall, Colman Moore, Gram Booth, Christa Hestekin, Melissa Moss 265-Pos Board B30 PROBING INTERACTIONS BETWEEN THE CURLI ACCESSORY PROTEIN CSGE AND HUMAN ISLET AMYLOID POLYPEPTIDE. Tanya J. Espino , Sharon Patray, Isamar Aranda, Karen Guerrero, Sajith Jayasinghe 266-Pos Board B31 NON-STANDARD PROTEIN ENGINEERING AT THE BOUNDARY OF MO- LECULAR MECHANICS AND QUANTUM CHEMISTRY: HALOGEN-BASED DESIGN OF INSULIN ANALOGS. Michael A. Weiss , Nelson F. Phillips, Faramarz Ismail-Beigi, Vijay Pandyarajan, Yanwu Yang, Yen-Shan Chen, Nalinda Wickramasinghe, Brian Smith, John G. Menting, Michael C. Law- rence, Krystel El-Hage, Markus Meuwly 267-Pos Board B32 SWEETER AND STRONGER: STRUCTURAL-DRIVEN MOLECULAR DESIGN TO ENHANCE SWEETNESS AND STABILITY OF THE SINGLE CHAIN MONEL- LIN MNEI. Serena Leone, Andrea Pica, Federica Donnarumma, Alessandro Emendato, Rocco Di Girolamo, Roberta Spadaccini, Piero A. Temussi, Delia Picone 268-Pos Board B33 MOLECULAR DETERMINANTS OF SPECIFICITY IN THE DPR-DIP INTERAC- TION NETWORK. Aiman Sherani , John M. Jumper, Engin Ozkan, Tobin R. Sosnick, Benoit Roux 269-Pos Board B34 PREDICTION OF PROTEIN AND RNA STRUCTURES BY CO-EVOLUTION: GOING BEYOND ANECDOTAL CASES TOWARDS LARGE-SCALE. Guido Uguzzoni, Shalini John Lovis, Francesco Oteri, Hendrik Szurmant, Weigt Martin, Alexander Schug 270-Pos Board B35 PROTEIN-PROTEIN COMPLEX STRUCTURE PREDICTION USING THE SOLU- TION THEORY IN THE ENERGY REPRESENTATION. Kazuhiro Takemura , Akio Kitao, Nobuyuki Matubayasi 271-Pos Board B36 REFINEMENT OF PROTEIN DOCKING WITH ATOM-ATOM CONTACT POTENTIALS, BACKBONE FLEXIBILITY AND SIDE-CHAIN REPACKING. Taras Dauzhenka , Ivan Anishchenko, Petras J. Kundrotas, Ilya A. Vakser 272-Pos Board B37 PROTEIN FOLDING UPON BINDING REVEALED BY MOLECULAR DYNAMICS SIMULATION. Chris Neale , Régis Pomès, Rachel Sterne-Marr, Angel García 273-Pos Board B38 USING MOLECULAR DYNAMICS SIMULATIONS TO UNDERSTAND PAT- TERN FORMATION IN POLYMERS . Anna Vernon , Paul Fenimore, Charlie Strauss, Chang-Shung Tung, Daan Frenkel, Eugene Terentjev 274-Pos Board B39 MOLECULAR INTERACTIONS OF CANNABINOID RECEPTOR INTERACTING PROTEIN 1 A AND B WITH CANNABINOID RECEPTOR 1 . Pratishtha Singh, Anjali Ganjiwale, Allyn C. Howlett, Sudha M. Cowsik

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