Biophysical Society 61st Annual Meeting | Program Guide

330-Pos Board B95 A COMPUTATIONAL INVESTIGATION INTO THE MECHANISM OF THE HIS- TONE ACETYLTRANSFERASE, GCN5. R. Hunter Wilson , Isaiah Sumner 331-Pos Board B96 MOLECULAR SIMULATIONS OF BACTERIAL LIPOPROTEIN BIOGEN- ESIS. Phillip J. Stansfeld 332-Pos Board B97 HEME TRAFFICKING BY THE CYTOCHROME C BIOGENESIS PATH- WAYS. Molly C. Sutherland , Joel A. Rankin, Robert G. Kranz 333-Pos Board B98 DESIGNED ENZYMES AND THE DRIVING FORCES BEHIND INTERDOMAIN ELECTRON TRANSFER. Mia C. Brown , Kelly Greenland, Lei Zhang, Ronald Board B99 FACTORS GOVERNING AUTOOXIDATION OF HUMAN HEMOGLOBIN.  Andres S. Benitez Cardenas , John S. Olson 335-Pos Board B100 ASSESSING THE SPECTROSCOPIC PROPERTIES AND ENZYME ACTIVITY OF FLUORESCENT CASPASE SUBSTRATES. Gena Lenti, Nicholas Tassone, Srirajkumar Ranganathan, Caitlin Karver, Cathrine A. Southern 336-Pos Board B101 SINGLE MOLECULE ENZYMOLOGY WITH OUTER MEMBRANE PROTEIN G. Bach G. Pham 337-Pos Board B102 PROTEIN SEMI-SYNTHESIS TO CHARACTERIZE PHOSPHO-REGULATION OF HUMAN UNG2. Brian P. Weiser , James T. Stivers, Philip A. Cole 338-Pos Board B103 VOLTAGE DEPENDENT PHOSPHATASE ACTIVITY IS ENHANCED BY INTRA- CELLULAR ACIDIFICATION. Angeliki Mavrantoni, Kirstin Hobiger, Dominik Oliver, Christian R. Halaszovich 339-Pos Board B104 ELECTRIC FIELD EFFECTS IN THE ACTIVE SITE OF A THERMOPHILIC ENZYME AS OBSERVED BY FTIR AND 2DIR SPECTROSCOPY. Tayler D. Hill , Hannah H. Lepird, David A. Price, Sean D. Moran 340-Pos Board B105 INFRARED STRUCTURAL BIOLOGY: HOW TO DETECT PROTONATION STATES OF HISTIDINE SIDE CHAINS IN PROTEINS. Aihua Xie , Charle Liu, Matthew Cavener 341-Pos Board B106 ORIGIN OF CHAIN LENGTH SPECIFICITES OF STARCH BRANCHING EN- ZYME. Hadi Nayebi Gavgani , Remie Fawaz, Zahra Assar, Alireza Ghanbar- pour, David Walls, Sarah McGovern, James H. Geiger 342-Pos Board B107 MODIFICATIONS OF ALPHA AND BETA CARBOXY-TERMINAL TAILS REGU- LATE MICROTUBULE SEVERING BY KATANIN. Madison Tyler , Corey Reed, Dan Sackett, Jennifer Ross Ribosomes and Translation (Boards B108–B110) 343-Pos Board B108 PROTEIN SYNTHESIS TIMES SCALE WITH GENE LENGTH BECAUSE THE DETERMINANTS OF TRANSLATION SPEED ARE RANDOMLY DISTRIBUTED ACROSS GENES. Edward P. O’Brien , Ajeet Sharma 344-Pos Board B109 THE ROLE OF L11 STALK FLUCTUATIONS IN AA-TRNA ACCOMMODA- TION. Huan Yang , Paul Charles Whitford L. Koder 334-Pos

317-Pos Board B82 NFΚB AND IΚBΑ ENGAGE IN AN ‘I FOLD YOU, YOU FOLD ME’ INTERAC- TION EXCLUDING DNA. Kristen M. Ramsey , Holly E. Dembinski, Yi Chen, Elizabeth A. Komives 318-Pos Board B83 HDXMS REVEALS DYNAMIC CHANGES IN THE ANTICOAGULANT W215A MUTANT OF THROMBIN. Riley Peacock , Jessie Davis, Sofia Zaragosa, Elizabeth Komives 319-Pos Board B84 INSIGHTS INTO DYNAMICS OF THROMBIN W215 MUTANTS USING SYNAPT G2SI WITH ION MOBILITY SEPARATION.  Jessie R. Davis , Riley Peacock, Elizabeth Komives 320-Pos Board B85 THE EFFECTS OF PROTEIN DYNAMICS ON IMMUNE SYSTEM SIGNALING PATHWAYS. Helen T. Hobbs , Susan Marqusee, John Kuriyan 321-Pos Board B86 IMATINIB BINDING TO HUMAN C-SRC IS COUPLED TO INTER-DOMAIN ALLOSTERY AND SUGGEST A NOVEL KINASE INHIBITION STRATEGY. Yuko Tsutsui , Daniel Deredge, Patrick L. Wintrode, Franklin A. Hays 322-Pos Board B87 A PHOSPHO-INDUCED THEFT OF A SALT BRIDGE IN RKIP LINKS MAP KINASE AND G PROTEIN-MEDIATED SIGNALING. Tobin R. Sosnick , John J. Skinner, Sheng Wang, Jiyoung Lee, Ruth Sommese, Sivaraj Sivaramakrish- nan, Wolfgang Kölmel, Maria Hirschbeck, Hermann Schindelin, Caroline Kisker, Kristina Lorenz, Marsha R. Rosner 323-Pos Board B88 CHARACTERIZATION OF DISEASE CAUSING MUTATIONS ASSOCIATED WITH FGF RECEPTOR TYROSINE KINASES USING NMR SPECTROSCO- PY. WilliamM. Marsiglia , Huaibin Chen, Min-kyu Cho, Moosa` Moham- madi, Nathaniel J. Traaseth 324-Pos Board B89 CONFORMATIONAL FLEXIBILITY OF HIV VIF IN COMPLEX WITH HOST PROTEINS. K. Aurelia Ball , John D. Gross, Matt P. Jacobson 325-Pos Board B90 BINDING-INTERFACE DYNAMICS BETWEEN CALMODULIN AND ITS TARGETS REVEALED USING NONPERTURBATIVE INFRARED PROBE GROUPS. Casey H. Londergan , Kristen L. Kelly 326-Pos Board B91 NEDD4-2 IS A FUNCTIONAL OLIGOMER EXHIBITING COOPERATIVE ALLO- STERIC KINETICS. Dustin R. Todaro , Allison C. Augustus-Wallace, Jennifer M. Klein, Arthur L. Haas 327-Pos Board B92 UBIQUITINATION OF SUBSTRATES BY E6AP/UBE3A LIGASE.  Virginia Ronchi , Arthur Haas 328-Pos Board B93 MECHANISTIC INSIGHTS INTO UBC13-CATALYZED UBIQUITINATION.  Isaiah Sumner , R. Hunter Wilson, Walker M. Jones, Aaron G. Davis, Serban Zamfir 329-Pos Board B94 CHARACTERIZATION OF THE ESSENTIAL RESIDUES OF CYCLOOXYGEN- ASE-1 AND -2 RESPONSIBLE FOR THEIR INTER-SUBUNIT COMMUNICA- TIONS UPON THEIR BINDING TO THE CORRESPONDING SUBSTRATES AND INHIBITORS.  Inseok Song Enzyme Function, Cofactors, and Post-translational Modifications (Boards B91–B107)

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