Biophysical Society 61st Annual Meeting | Program Guide

Voltage-gated Ca Channels I (Boards B299–B308)

546-Pos Board B311 NOVEL INSIGHTS FROM STRUCTURAL ANALYSIS OF INTERACTIONS OF KCNQ K + CHANNELS WITH CALMODULIN. Crystal R. Archer , Akash Bhat- tacharya, Benjamin T. Enslow, Alex B. Taylor, Dmitri N. Ivanov, Mark S. Board B312 KCNE1 AND KCNE3 MODULATE KCNQ1 CHANNELS BY AFFECTING DIFFER- ENT GATING TRANSITIONS. Rene Barro-Soria , Rosamary Ramentol, Sara I. Liin, Marta E. Perez, Robert S. Kass, H Peter Larsson 548-Pos Board B313 CP1 OPENS I KS CHANNELS BY SUBSTITUTING PIP 2 . Moawiah M. Naffaa , Xianjin Xu, Hongwu Liang, Guohui Zhang, Hong Zhan Wang, Junyuan Goa, Ira S. Cohen, Xiaoqin Zou, Jianmin Cui 549-Pos Board B314 PI(4,5)P 2 MODULATES HYSTERESIS AND PHARMACOLOGY OF K V 7 CHAN- NELS. Carlos A. Villalba-Galea 550-Pos Board B315 MOLECULAR MECHANISM OF THE KV7.1-CHANNEL ACTIVATOR N-ARA- CHIDONOYL TAURINE. Sara I. Liin , Rene Barro-Soria, H Peter Larsson 551-Pos Board B316 ML277 OPENS KCNQ1 CHANNELS BY SELECTIVELY ENHANCING THE AO STATE. Panpan Hou , Ling Zhong, Powei Kang, Zachary Beller, Kelli McFar- land, Jingyi Shi, Jianmin Cui 552-Pos Board B317 COMPREHENSIVE ASSESSMENT OF DISEASE MUTANT FORMS OF THE HU- MAN KCNQ1 POTASSIUM CHANNEL. Hui Huang , Keenan Taylor, Charles Board B318 A VOLTAGE- TO LIGAND- GATED SWITCH IN VOLTAGE-GATED POTASSIUM CHANNELS. Xiaoping Pi , Qiang Ding, Zhaobing Gao 554-Pos Board B319 VOLTAGE AND CA 2+ SENSOR COUPLING MODULATION BY Β SUBUNITS IN THE BK CHANNEL. Yenisleidy Lorenzo , Karen Castillo, Gustavo Contreras, Willy Carrasquel-Ursulaez, Carlos Gonzalez, Ramon Latorre 555-Pos Board B320 ALPHA-B HELIX OF RCK1 IS A MAJOR TRANSDUCTION PATHWAY FOR CA 2+ ACTIVATION OF BK CHANNELS. Yanyan Geng , Zengqin Deng, Gonzalo Budelli, Alice Butler Butler, Jianmin Cui, Peng Yuan, Lawrence Salkoff, Karl Board B321 CARBON MONOXIDE MAY REGULATE BK SLO1 CHANNEL ACTIVITY BY PARTIALLY DISRUPTING HEME COORDINATION. Taleh Yusifov , Nicoletta Savalli, Antonios Pantazis, Stefan H. Heinemann, Toshinori Hoshi, Riccardo Olcese 557-Pos Board B322 ROLE OF THE SLO1 CRAC4 MOTIF IN BK CHANNEL’S ETHANOL SENSITIVI- TY. Maria N. Simakova , Dasha Zaytseva, Shivantika Bisen, Alex M. Dopico, Anna N. Bukiya 558-Pos Board B323 DIFFERENTIAL EXPRESSION OF BK CHANNEL BETA1 SUBUNITS IN RAT MESENTERIC, CORONARY AND CEREBRAL ARTERIES. Guruprasad Kuntamallappanavar , Shivantika Bisen, Anna Bukiya, Alex Dopico 559-Pos Board B324 FUNCTIONAL COUPLING OF BK CHANNELS TO NMDA RECEPTORS IN HIP- POCAMPAL DENTATE GYRUS. Xin Guan , Jiyuan Zhang, Qin Li, Hui-Lin Pan, Jiusheng Yan Shapiro 547-Pos Sanders 553-Pos Magleby 556-Pos

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534-Pos Board B299 MODELING THE EFFECTS OF VOLATILE ANESTHETICS ON L-TYPE CA 2+ CHANNELS AND CA 2+ INDUCED CA 2+ RELEASE IN CARDIOMYO- CYTES. Neeraj Manhas 535-Pos Board B300 ELECTROPHYSIOLOGICAL CHARACTERIZATION OF T-TYPE CALCIUM CHAN- NELS IN CENTRAL MEDIAL NUCLEUS OF THE RAT THALAMUS. Tamara Timic Stamenic , Slobodan M. Todorovic 536-Pos Board B301 CID Travel Awardee UNMASKING THE MOLECULAR DETERMINANTS IMPORTANT FOR CA 2+ -DEPENDENT REGULATION OF CA V 2.2.  Jessica R. Thomas , Jussara Hagen, Board B302 CID Travel Awardee C-TERMINAL SPLICE VARIATION REVEALS NEW INSIGHTS INTO CALMOD- ULIN REGULATION OF CA V 1.4 CHANNELS. Brittany Williams , Vasily Kerov, Daniel Soh, Amy Lee 538-Pos Board B303 STRUCTURAL CHARACTERIZATION OF CALMODULIN DISEASE MUTA- TIONS. Kaiqian Wang , Jocelyn Lu, Kamilla T. Larsen, Michael T. Overgaard, Filip Van Petegem 539-Pos Board B304 STRONTIUM AND BARIUM IN AQUEOUS SOLUTION AND AN ION CHAN- NEL BLOCKING SITE. Mangesh Chaudhari , Susan Rempe 540-Pos Board B305 THE CALCIUM CHANNEL A2D SUBUNIT INCREASES THE GATING CHARGES OF CAV1.2 CHANNELS. Gustavo F. Contreras , Nicoletta Savalli, Antonios Pantazis, Carlos Gonzalez, Riccardo Olcese, Alan Neely 541-Pos Board B306 CALMODULIN AND STAC3 ENHANCE FUNCTIONAL EXPRESSION OF CA V 1.1.  Jacqueline Niu , Manu Ben Johny, David T. Yue, Takanari Inoue 542-Pos Board B307 CA V 1.3 ( CACNA1D ) GAIN-OF-FUNCTION DE NOVO MISSENSE MUTATIONS ARE ASSOCIATED WITH CNS DISORDERS. Alexandra Pinggera , Luisa Mack- enroth, Jörg Striessnig 543-Pos Board B308 DUAL EFFECT OF PALMITATE ON VOLTAGE-GATED CALCIUM CHANNELS AND INSULIN SECRETION IN PANCREATIC BETA CELLS OF RATS. Neivys García-Delgado , Myrian Velasco-Torres, Carmen Sanchez-Soto, Marcia Hiriart Voltage-gated K Channels and Mechanisms of Voltage Sensing and Gating I (Boards B309–B324) 544-Pos Board B309 Education Travel Awardee EXAMINING THE ROLE OF PHOSPHORYLATION ON INTERACTIONS BETWEEN THE CARDIAC POTASSIUM CHANNEL ALPHA-SUBUNITS HERG AND K V LQT1. Medeea C. Popescu , Louise E.O. Darling 545-Pos Board B310 MONITORING STRUCTURAL REORGANIZATION OF CALMODULIN IN COM- PLEX WITH THE C-TERMINUS OF KCNQ CHANNELS. Carolina Gomis-Perez , Eider Nunez-Viadero, Ganeko Bernardo-Seisdedos, Cova- donga Malo, Pilar Areso, Alvaro Villarroel Amy Lee 537-Pos

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