Biophysical Society 61st Annual Meeting | Program Guide

CID Committee Meeting 8:30 am - 10:30 am, Room 203 Career Center Workshop Ten Tough Industrial Interview Questions (and You’ve been invited to interview with that drug development company that you’ve always wanted to work for. You’ve soaked up the details of the position description. You are confident in your ability to do the job, as well as answer any/all technical questions during the interview process. The day is yours…until…that first question catches you by surprise and your confidence begins to wilt. Be prepared for those non-technical ques- tions that you will almost certainly hear at some point, know why they are asked, and learn what a good (if not great) response to each question might be by attending this workshop. Exhibits 10:00 am - 5:00 pm, Hall B-2 & C Coffee Break 10:15 am - 11:00 am, Hall B-2 & C New Member Welcome Coffee 10:15 am - 11:15 am, Rivergate Room, Lobby Level Calling all new BPS members! Come and mingle with BPS Staff, Soci- ety Council, and programmembers as you learn about the Society’s activities. Current members are welcome to come and meet with new members. Exhibitor Presentation Beckman Coulter Life Sciences 10:30 am - 12:00 pm, Room 221 What Goes Around, Comes Around: Unveiling the Optima AUC For more than 70 years, Analytical Ultracentrifugation (AUC) has played a critical role in laying the foundations for modern molecular biology. AUC allows for the characterization of proteins, oligomers, aggregates, particles, colloids, nanoparticles, extracellular vesicles and other small structures in native conditions and matrix-free conditions. By measuring proteins and other macro-molecules as interacting elements instead of in isolation, AUC more closely approximates true physiological conditions offering unique insight into molecular characterization and processes including molecular weight determination/conformation, stoichiometry, heterogeneity as well as thermodynamic parameters associated with binding. Following a brief overview of the fundamentals of AUC operation and analysis, the talk will include a brief introduction of the new Optima AUC system. Comparative data from the new Optima AUC versus the Pro- teomeLab series will be presented, while highlighting applications that are now enabled in the new system due to multi-wavelength analysis and faster scan speeds. Analytical Ultracentrifugation is a complementary technique to many oth- ers; the talk will illuminate advantages of AUC over existing techniques for different applications. Lastly, future research fields enabled by the new Optima AUC will be discussed. Speaker Chad Schwartz, AUC Product Manager, Beckman Coulter Life Sciences Ten Pretty Good Responses) 10:00 am - 11:00 am, Room 212/213

Symposium Future of Biophysics 10:45 am - 12:45 pm, Great Hall A Support contributed by the Burroughs Wellcome Fund Co-Chairs David W. Piston, Washington University Catherine W. Royer, Rensellaer Polytechnic Institute No Abstract 10:45 am X-RAY VISION INTO THE WORLD OF ENZYMES.  Nozomi Ando No Abstract 11:05 am BACTERIAL TYPE 3 SECRETION SYSTEMS: HIGH-THROUGHPUT 3D SINGLE- MOLECULE TRACKING OFSORTING PLATFORM PROTEINS IN LIVE CELLS.  Andreas Gahlmann No Abstract 11:25 am SCANNING HE ION- AND NONLINEAR OPTICAL MICROSCOPY COMBINED WITH FORCE MEASUREMENTS FOR THE CHARACTERIZATION OF SPIDER SILK.  Irina Iachina No Abstract 11:45 am REPURPOSING MECHANOSENSITIVE CHANNELS TO STUDY CONFINED 3D CELL MIGRATION .  Allen Liu No Abstract 12:05 pm PHOSPHORYLATION INDUCES SEQUENCE-SPECIFIC CONFORMATIONAL SWITCHES IN THE RNA POLYMERASE II C-TERMINAL DOMAIN.  Scott A. Showalter No Abstract 12:25 pm REAL-TIME QUANTIFICATION OF SINGLE RNA TRANSLATION DYNAMICS IN LIVING CELLS.  Timothy J. Stasevich Symposium TRP Channels 10:45 am - 12:45 pm, Great Hall B Chair Sharona E. Gordon, University of Washington 830-Symp 10:45 am MECHANISMS OF TRPV1 ION CHANNEL GATING.  Sharona E. Gordon No Abstract 11:15 am GLEANING FUNCTIONAL INSIGHTS FROM TRP CHANNEL STRUCTURES.  David Julius 831-Symp 11:45 am COMPUTATIONAL APPROACHES TO THE STUDY OF TRPV CHANNEL ACTIVATION AND MODULATION APPROACHES TO THE STUDY OF TRPV CHANNEL ACTIVATION AND MODULATION.  Carmen Domene 832-Symp 12:15 pm NEW INSIGHTS INTO THE FUNCTION OF TRPV CHANNELS.  Vera Moiseenkova Bell Platform Protein-Nucleic Acid Interactions I 10:45 am - 12:45 pm, Room R02/03 Co-Chairs Dagmar Klostermeier, University of Munster, Germany Candice Etson, Wesleyan University

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