Biophysical Society 61st Annual Meeting | Program Guide

Speed Networking 2:30 pm - 3:30 pm, Mosaic Lounge, Lobby A

Colloidal stability in contrast, is a property that describes extrinsic behav- ior of proteins in a bulk solution, and can be a key attribute in ensuring product quality. The most commonly observed properties to quantify colloidal stability include the diffusion interaction parameter (k D ), second virial coefficient (B 22 ), zeta potential (ζ), viscosity (η) and hydrodynamic size (r h ). The workshop will introduce a newly developed technique called Taylor Dispersion Analysis (TDA), which provides an automated method for analysis of hydrodynamic size and k D using small volumes of sample (<5uL) without the need for serial dilutions. This presentation will compare and contrast the results of Taylor Dispersion Analysis to that of traditional analysis methods to further understand the complimentary nature of these results. Speaker MatthewMcGann, Product Manager, Innovation Products, Malvern Instruments Biophysics 101 Cryo-electron Microscopy (Cryo-EM) 1:30 pm - 3:00 pm, Room 214 Cryo electron microscopy is booming, with new atomic structures ap- pearing every week and new facilities being installed at research centers across the globe. This unprecedented growth has been stimulated by the availability of new imaging detectors that dramatically increase the acuity of images, but also reflects advances in electron microscopes and image analysis software. These technologies are being employed for two main applications, known as single-particle analysis and tomography, which can be used to produce structures of a wide range of biomolecu- lar assemblies, from isolated molecules to cells and tissues. This year’s “Biophysics 101” will discuss both the technologies and the applications to provide insight into why cryo-EM has become such a powerful and essential tool in structural biology. Session Chair Erin Schexnaydre, Lousiana State University Presenters Esther Bullitt, Boston University School of Medicine David DeRosier, Brandeis University David Stokes, New York University School of Medicine Snack Break 1:45 pm - 3:00 pm, Hall B-2 & C How to Get Your Scientific Paper Published 2:15 pm - 3:45 pm, Room 220 This panel discussion, will focus on the practical issues involved in publishing a scientific paper. The panelists have extensive experience in writing, reviewing, and editing papers, and will provide information on the dos and don’ts of submitting research manuscripts. Discussions will focus on strategies to avoid common pitfalls, how to prevent and fix problems before submission, and how to respond to critiques and even rejection of a paper. Attendees are encouraged to ask questions during the session. Moderators Enrique De La Cruz, Yale University Gail Robertson, University of Wisconsin-Madison Panelists Cynthia Czajkowski, University of Wisconsin-Madison Jane Dyson, Scripps Research Institute Chris Yip, University of Toronto

Career development and networking is important in science, but can be a big time commitment. Here we offer refreshments and the chance to speed network, an exciting way to connect with a large number of biophysicists in a short amount of time. This is an ideal opportunity for graduate students to meet prospective postdoc mentors and faculty to find a postdoc. Early career scientists could use their new contacts to discuss career goals and challenges, get advice on tenure or grant writing, find out how to gain recognition, or network for your next job. Mid-career and more experienced scientists could learn how to get more involved in the Society or network for possible reviewers for papers. After introductions, each person will have short 3-5 minute meetings with consecutive new contacts. During this time you can exchange information and ask questions. When time is up, you select the next person to talk to. By the end of the event, each participant will have had meaningful inter- actions with over half a dozen colleagues and the opportunity to meet many more. It’s that simple! Career Center Workshop Beyond the Bench: Preparing for Your Career Transition in the Life Sciences 2:30 pm - 3:30 pm, Room 212/213 There are numerous alternative career options for the seasoned bench scientist who may have decided to take his/her talents and apply them in a new direction. This transition can be accomplished without having to matriculate in another graduate program, and this session explores the how’s and why’s of making such a transition. Be prepared to talk about the role you are thinking about moving into, why you may have chosen this alternative path, and what successes you may have had thus far. A Driving Force in the Middle of the Journey Funding Opportunities for Mid-Career Scientists 2:30 pm - 4:00 pm, Room 219 This session features a discussion of funding opportunities for mid-career researchers – those who fall in between the “new investigator” and “senior researcher” career stages. Panelists will discuss options and offer their points of view on how to maximize and strategize about funding opportunities. Speakers Nancy Carrasco, Yale University German Cavelier, Fordham University Frances Separovic, University of Melbourne, Australia Engin Serpersu, NSF

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