Biophysical Society 61st Annual Meeting | Program Guide

Symposium Mitochondrial Dynamics and Transport 4:00 pm - 6:00 pm, Great Hall B

895-Plat 4:30 pm THICK FILAMENT COMPLIANCE IN PASSIVELY STRETCHED SKELETAL MUSCLE. Weikang Ma, Danielle Buck, Joshua Nedrud, Thomas C. Irving , Henk Granzier 896-Plat 4:45 pm EVIDENCE FOR AN I-BAND SPRING THAT IS TUNED TO THE LENGTH OF THE SKELETAL MUSCLE SARCOMERE.  Joseph D. Powers , Massimo Recon- diti, Luca Fusi, Elisabetta Brunello, Vincenzo Lombardi, Gabriella Piazzesi 897-Plat 5:00 pm ACTIVATED SKELETAL MUSCLE MYOFIBRILS HAVE DIFFERENT PEAK STRESSES AT SIMILAR SARCOMERE LENGTHS WHEN LENGTHENED BE- YOND MYOFILAMENT OVERLAP.  Tim R. Leonard , Walter Herzog 898-Plat 5:15 pm International Travel Awardee SARCOMERE AND INTER-SARCOMERE DYNAMICS WITHIN SKELETAL MUSCLE MYOFIBRILS.  Felipe de Souza Leite , Dilson E. Rassier 899-Plat 5:30 pm THIN FILAMENT POINTED ENDS REDISTRIBUTE IN RESPONSE TO ALTERED THICK FILAMENTS.  Ryan Littlefield 900-Plat 5:45 pm ACTA1-RELATED NEMALINE MYOPATHY MUTATIONS ENGENDER A RANGE OF STRUCTURAL AND FUNCTIONAL PHENOTYPES IN DROSOPHILA INDI- RECT FLIGHT MUSCLES.  Aditi Madan , Meera C. Viswanathan, Manuela Lavorato, William Schmidt, Julien Ochala, Anthony Cammarato Platform Ion Channel Regulatory Mechanisms 4:00 pm - 6:00 pm, Room R06/07 Co-Chairs Coeli M. Lopes, University of Rochester Gaya P. Yadav, University of Texas Southwestern Medical Center 901-Plat 4:00 pm SMALL MOLECULE MODULATION OF BRAIN GIRK CHANNELS MOLECULE MODULATION OF BRAIN GIRK CHANNELS.  Ian W. Glaaser , Paul A. 4:15 pm BK CHANNEL Α AND Γ1 SUBUNITS ASSEMBLE WITH A STOICHIOMETRY OF UP TO 4:4, BUT ONE Γ1 IS SUFFICIENT TO PRODUCE THE FULL Γ1- INDUCED GATING SHIFT.  Vivian Gonzalez-Perez , Manu Ben-Johny, Xiao- Ming Xia, Christopher J. Lingle 903-Plat 4:30 pm SUMOYLATION OF NA V 1.2 CHANNELS MEDIATES THE EARLY RESPONSE TO ACUTE HYPOXIA IN CENTRAL NEURONS.  Leigh D. Plant , Jeremy D. Marks, Steve A.N. Goldstein 904-Plat 4:45 pm STOICHIOMETRIES OF HCN-KCNE2 CHANNEL.  Yoann Lussier, Lena Möller, Oliver Fürst, Rikard Blunck, Nazzareno D’Avanzo 905-Plat 5:00 pm MOLECULAR INTERACTIONS BETWEEN KV4.3 AND DPP6 - THE BIOCHEM- ICAL ANATOMY OF IDIOPATHIC VENTRICULAR FIBRILLATION.  Nazlee Sharmin , Peter Mohler, Rikard Blunck, Stanley Nattel 906-Plat 5:15 pm CHARACTERIZATION OF THE ORAI-CALMODULIN INTERACTION AS PO- TENTIAL MEDIATOR OF CALCIUM-DEPENDENT ORAI-CHANNEL INACTIVATION.  Lukas Traxler , Felix Faschinger, Petr Rathner, Michael Stadlbauer, Tatsiana Charnavets, Christoph Romanin, Norbert Müller, Peter Hinterdorfer, Hermann J. Gruber Slesinger 902-Plat

M O N D A Y

Chair Robert S. Balaban, NIH 885-Symp

4:00 pm THE MUSCLE CELL MITOCHONDRIA RETICULUM.  Robert S. Balaban 886-Symp 4:30 pm CONTROL OF MITOCHONDRIAL FUNCTION BY FUSION AND FISSION.  Hsiuchen Chen, David Chan 887-Symp 5:00 pm STRUCTURE AND IN SITU ORGANIZATION OF ATP SYTHASE AND RESPIRA- TORY CHAIN COMPLEXES.  Karen Davies , Alexander Muehleip, Thorsten Blum, Bertram Daum, Claudio Anselmi, José Faraldo-Gómez, Werner 5:30 pm MITOCHONDRIA AND MEMORY: BIOENERGETICS, SYNAPTIC PLASTICITY AND NEURODEGENERATION.  Elizabeth A. Jonas , Nelli Mnatsakanyan, Paige Miranda, Han-A Park, Rongmin Chen, Pawel Licznerski, Maria Weinert, Peter J.S. Smith, Andres Chavez, R. Suzanne Zukin, Valentin K. Gribkoff, Kambiz N. Alavian Symposium Epigenomic Changes Driven by Biomechanical Load 4:00 pm - 6:00 pm, Room R02/03 Chair Andrew D. McCulloch, University of California, San Diego 889-Symp 4:00 pm SYSTEMS MECHANOBIOLOGY OF CARDIAC MYOCYTES.  Andrew D. 4:30 pm THE “SELF-STIRRED” GENOME: BULK AND SURFACE DYNAMICS OF THE CHROMATIN GLOBULE.  Alexandra Zidovska 891-Symp 5:00 pm EPIGENETIC REGULATION OF CHROMATIN DYNAMICS. Michael G. Poirier 892-Symp 5:30 pm MULTI-SCALE MODELING OF CHROMOSOMAL DNA IN PROKARYOTIC AND EUKARYOTIC CELLS.  Andrew J. Spakowitz Platform Skeletal Muscle Mechanics, Structure, and Regulation 4:00 pm - 6:00 pm, Room R04/05 Co-Chairs Kühlbrandt 888-Symp McCulloch 890-Symp STRUCTURAL KINETICS OF THE RLC DOMAIN OF MYOSIN DURING ACTI- VATION OF SKELETAL MUSCLE FIBERS BY PHOTOLYSIS OF CAGED-CALCI- UM.  Luca Fusi , Elisabetta Brunello, Ziqian Yan, Malcolm Irving 894-Plat 4:15 pm STRUCTURAL CHANGES IN THE THICK FILAMENTS DURING ACTIVATION OF DEMEMBRANATED SKELETAL MUSCLE FIBERS. Marco Caremani, Luca Fusi, Massimo Reconditi, Gabriella Piazzesi, Theyencheri Narayanan, Malcolm Irving, Vincenzo Lombardi, Elisabetta Brunello Luca Fusi, King’s College London, United Kingdom Felipe de Souza Leite, McGill University, Canada 893-Plat 4:00 pm

61