Biophysical Society 61st Annual Meeting | Program Guide

973-Pos Education Travel Awardee DEGRADATION OF CALPONIN 2 IS REQUIRED FOR CYTOKINESIS. Dipak Maskey , Airong Qian, Jian-Ping Jin 974-Pos Board B42 INSULIN STRUCTURE AND STABILITY ASSESSED BY INTRINSIC FLUO- RESCENCE AND SIMULTANEOUS UV-VIS ABSORBANCE SPECTROSCOPY COUPLED WITH CHEMOMETRIC ANALYSIS. Karen E. Steege Gall , Mari- nella Sandros 975-Pos Board B43 MACROMOLECULAR CROWDING EFFECTS ON PRESSURE-INDUCED PRO- TEIN FOLDING/UNFOLDING. Andrei G. Gasic , Dirar Homouz, Margaret S. Board B44 EXAMINING THE STABILITY OF Β-SHEETS USING THE CHARMM DRUDE POLARIZABLE FORCE FIELD. Anthony Hazel , James C. Gumbart 977-Pos Board B45 HYDROPHOBIC BURIAL AND DYNAMIC CONFORMATIONS OF ESTROGEN RECEPTOR N-TERMINUS. Sichun Yang , Yi Peng Protein Assemblies I (Boards B46–B58) 978-Pos Board B46 STUDYING PEPTIDE AGGREGATION USING MIXED ALL-ATOM/COARSE GRAIN MOLECULAR DYNAMICS SIMULATIONS.  John C. Shelley , Mee Shel- ley, Myvizhi Esai Selvan, Jun Zhao, Volodymyr Babin, Chenyi Liao, Jianing Li 979-Pos Board B47 MOLECULAR MECHANISM OF SURFACE-ASSISTED SELF-ASSEMBLY OF AMYLOID-LIKE PEPTIDES. Seung-gu Kang 980-Pos Board B48 VARIABLE BINDING OF THIOFLAVIN T BY AMYLOID FIBRILS. Hiroaki Komatsu , Claire Meurice, Giuseppe Grasso, Lisa G. Lippert, Yale E. Gold- man, Paul H. Axelsen 981-Pos Board B49 THE LEVINTHAL PROBLEM IN AMYLOID AGGREGATION: IDENTIFICATION OF GOOD COORDINATES IN A FLAT REACTION SPACE. Zhiguang Jia, Jian- han Chen, Jeremy D. Schmit 982-Pos Board B50 PREDICTION OF PROTEIN AGGREGATION PROPENSITIES USING GOR METHOD. Maksim Kouza, Girik Malik, Eshel Faraggi, Andrzej Kolinski, Irina Buhimschi, Andrzej Kloczkowski 983-Pos Board B51 A GENERAL FRAMEWORK FOR THE BOUNDARY STRUCTURE IN MULTI- COMPONENT SEDIMENTATION VELOCITY WITH REVERSIBLE INTERAC- TIONS. Peter Schuck , Sumit K. Chaturvedi, Huaying Zhao 984-Pos Board B52 DESIGNED CELL-PENETRATING PEPTIDES FOR INHIBITION OF AMYLOID- BETA (AΒ) AMYLOID FORMATION AND CYTOTOXICITY. Anja Henning- Knechtel , Mazin Magzoub 985-Pos Board B53 FLUORESCENCE DETECTED SEDIMENTATION VELOCITY ANALYTICAL ULTRACENTRIFUGATION FOR INVESTIGATING AFFINITY AND STOICHIOM- ETRY OF PROTEIN INTERACTIONS. Huaying Zhao , Sumit Chaturvedi, Peter Schuck 986-Pos Board B54 AUC SEDIMENTATION VELOCITY STUDIES OF THERAPEUTIC PROTEINS IN SERUM. Robert T. Wright , Walter F. Stafford, Peter J. Sherwood, John J. Corriea Board B41 Cheung 976-Pos

959-Pos Board B27 NOVEL METHOD FOR THE DESIGN OF A NEW ALPHA-HELICAL FOLD.  Taylor R. Crawford , Shivarni Patel, Danielle MacArt, Hyun Joo, Jerry Tsai 960-Pos Board B28 HIGH-THROUGHPUT PROTEIN DESIGN REVEALS QUANTITATIVE PROTEIN STABILITY REQUIREMENTS. Gabriel J. Rocklin , Tamuka Chidyausiku, Inna Goreshnik, Alex Ford, Scott Houliston, Cheryl Arrowsmith, David Baker 961-Pos Board B29 LUTE (LOCAL UNPRUNED TUPLE EXPANSION): ACCURATE CONTINUOUSLY FLEXIBLE PROTEIN DESIGN WITH GENERAL ENERGY FUNCTIONS AND RIGID-ROTAMER-LIKE EFFICIENCY. Mark A. Hallen , Jonathan D. Jou, Bruce R. Donald 962-Pos Board B30 A DEEP-DIVE INTO THE ROSETTA ENERGY FUNCTION FOR BIOLOGICAL MACROMOLECULES. Rebecca F. Alford , Andrew Leaver-Fay, Jeliazko R. Jeliazkov, Michael S. Pacella, Brian Kuhlman, Tanja Kortemme, Jeffrey J. Gray 963-Pos Board B31 FRACTAL NATURE OF PROTEIN INTERIOR AND ITS IMPLICATIONS FOR PROTEIN FUNCTION. Alexandr P. Kornev , Susan S. Taylor Protein Folding: Dynamics and Novel Methods (Boards B32–B45) 964-Pos Board B32 HOW DO COSOLUTES STABILIZE MACROMOLECULES? FROM BRIDGING TO DEPLETION ATTRACTION. Liel Sapir , Daniel Harries 965-Pos Board B33 THREE-STRAND Β-SHEET PEPTIDE MODELS. IR, VCD AND ECD SPECTRA, T-JUMP DYNAMICS AND NMR STRUCTURES SUPPORT MD AND DFT SIMULATATIONS. Timothy A. Keiderling , Heng Chi, Dan McElheny, Allen Walker, David Scheerer, Karin Hauser 966-Pos Board B34 NANOPORE IONIC CURRENT CAN REPORT ON THE FOLDING STATE OF A PROTEIN. Wei Si , Aleksei Aksimentiev 967-Pos Board B35 SIMULATING FORCE RESPONSE AT CELLULAR JUNCTIONS: DESMOPLAKIN AS A MOLECULAR FORCE SENSOR? Csaba Daday , Frauke Gräter 968-Pos Board B36 COMPLEX DYNAMICS IN SINGLE MOLECULE FORCE SPECTROSCOPY FROM SIMPLE SIMULATION MODELS. David De Sancho , Robert B. Best 969-Pos Board B37 DYNAMIC ESTIMATION OF FRET CORRECTION FACTORS TO STUDY REDOX PROTEIN INTERACTIONS. Halil Bayraktar , Selen Manioglu 970-Pos Board B38 FAST CALCULATION OF PROTEIN-PROTEIN BINDING FREE ENERGIES US- ING UMBRELLA SAMPLING WITH A COARSE-GRAINED MODEL.  Jagdish Suresh Patel , F. Marty Ytreberg 971-Pos Board B39 ULTRAFAST PROTEIN FOLDING THROUGH POLAR INTERACTIONS IN MEM- BRANE-MIMETIC ENVIRONMENTS. Georg Krainer , Andreas Hartmann, Abhinaya Anandamurugan, Pablo Gracia, Sandro Keller, Michael Schlierf 972-Pos Board B40 MONTE CARLO SIMULATIONS OF THE EFFECT OF A TURN SEQUENCE IN AN ALANINE-BASED PEPTIDE. Shiloh M. Nold

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