Biophysical Society 61st Annual Meeting | Program Guide

1026-Pos Education Travel Awardee EXPLORING THE ROLE OF FLEXIBILITY IN BINDING KINETICS AND AFFIN- ITY OF PKID-KIX THROUGH COARSE GRAINED SIMULATIONS. Talant A. Ruzmetov , John J. Portman 1027-Pos Board B95 DYNAMICAL PROPERTIES OF FLEXIBLE PEPTIDES ARE MODIFIED BY COVA- LENT FLUOROPHORE ATTACHMENT: A COMBINED FLUORESCENCE AND MOLECULAR DYNAMICS STUDY. Anders Barth , Manuel P. Luitz, Alvaro H. Crevenna, Rainer Bomblies, Martin Zacharias, Don C. Lamb 1028-Pos Board B96 DISORDERED TOXIN: THE MECHANISM OF TRANSCRIPTION REGULATION OF THE PSEUDOMONAS PUTIDA GRATA OPERON. Ariel Talavera Perez 1029-Pos Board B97 THE ROLE OF INTRINSICALLY DISORDERED LINKER AND SALT TYPE ON COOPERATIVITY OF E. COLI SSB BINDING TO SSDNA. Alexander G. Kozlov , Min Kyung Shinn, Timothy M. Lohman 1030-Pos Board B98 LATTICE MODELS FOR MODELING SEQUENCE-SPECIFIC PHASE BEHAVIOR OF LOW COMPLEXITY DOMAINS.  Jeong-Mo Choi , Rohit V. Pappu 1031-Pos Board B99 INTRINSICALLY DISORDERED PROTEIN DYNAMICS UNCOVERED THROUGH DYNAMIC FLEXIBILITY INDEX (DFI) ANALYSIS. Tushar Modi , Gül H. Zerze, Jeetain Mittal, Sara M. Vaiana, S. Banu Ozkan 1032-Pos Board B100 A STUDY OF DISORDER-TO-ORDER TRANSITION BY CHARACTERIZING THE BINDING PARTNERS USING A STATISTICAL POTENTIAL.  Iqbal Sumaiya , Hoque Md Tamjidul 1033-Pos Board B101 SINGLE-MOLECULE FRET PROBES A TRANSIENT COMPLEX THAT FACILI- TATES BINDING OF AN INTRINSICALLY-DISORDERED PROTEIN. Jae-Yeol Kim, Fanjie Meng, Hoi Sung Chung 1034-Pos Board B102 THERAPEUTIC POTENTIAL OF PEPTIDES DERIVED FROM INTRINSICALLY DISORDERED PROTEIN REGIONS. Stephen Beesley, Efrosini Artikis, Ewa Bienkiewicz 1035-Pos Board B103 ENSEMBLE AND SINGLE MOLECULE BIOPHYSICAL STUDIES OF TDP43. Phoebe S. Tsoi , Kyoungjae Choi, Josephine C. Ferreon, Allan Chris M. Ferreon 1036-Pos Board B104 GRP78 IS A MAJOR RIBOSYLATED PROTEIN IN CHO CELLS. Rong-Qiao He , Yang Lu, Bei Bei Wu, Le Xiang YU, Chan Shuai Han, Yan Wei 1037-Pos Board B105 THE IMPACT OF IDPS ON CIRCADIAN RHYTHMS.  Jennifer M. Hurley Transcription (Boards B106–B119) 1038-Pos Board B106 SINGLE-CELL, SINGLE-MRNA ANALYSIS OF CCNB1 PROMOTER REGULATION. Nidhi Vishnoi, Jie Yao 1039-Pos Board B107 VISUALIZATION OF ACTIVE TRANSCRIPTION SITES IN HUMAN CARDIO- MYOCYTES SUPPORTS THE CONCEPT OF BURST-LIKE TRANSCRIPTION OF MYH7 . Kathrin Kowalski , Ante Radocaj, Cristobal G. dos Remedios, Anto- nio Francino, Francisco Navarro-López, Theresia Kraft, Bernhard Brenner Board B94

1013-Pos Board B81 IN VITRO RECONSTITUTION TO UNDERSTAND THE MECHANISM OF BAM. Pamela A. Doerner , Marcelo C. Sousa 1014-Pos Board B82 SIDE CHAIN HYDROPHOBICITY SCALE USING THE TILTED BETA-BARREL PROTEIN PAGP. Dagan Marx , Karen Fleming 1015-Pos Board B83 DIFFERENCES IN THE ASSOCIATION OF BH3-ONLY PROTEINS TO BIOLOGI- CAL MEMBRANES. Vicente Andreu-Fernandez, Maria J. Garcia-Murria, Manuel Baño-Polo, Luis Martinez-Gil, Mar Orzaez, Ismael Mingarro 1016-Pos Board B84 POLYMER-MEDIATED SYNTHESIS AND INCORPORATION OF MEMBRANE PROTEIN IN PHOSPHOLIPID VESICLES. Tao Jiang , Ting Xu Intrinsically Disordered Proteins (IDP) and Aggregates I (Boards B85–B105) 1017-Pos Board B85 ENGINEERING PROTEASE-TRIGGERED DISASSEMBLY OF INTRINSICALLY DISORDERED PROTEIN DROPLETS. Benjamin S. Schuster , Ranganath Parthasarathy, Ellen H. Reed, Daniel A. Hammer 1018-Pos Board B86 SURFACE SOLVATION TUNES MOLECULAR-RECOGNITION PLASTICITY IN IDPS. Aritra Chowdhury , Iker Valle Aramburu, Piau Siong Tan, Edward A. Lemke 1019-Pos Board B87 Education Travel Awardee CONFORMATION PLASTICITY AND PEPTIDOGLYCAN CLEAVAGE BY THE N-TERMINAL INTRINSICALLY DISORDERED DOMAIN OF CHIZ. Cristian A. Escobar , Riqiang Fu, Timothy A. Cross 1020-Pos Board B88 ZINC BINDING INDUCES CONFORMATIONAL CHANGES IN THE LARGE INTRACELLULAR LOOP OF THE HUMAN ZINC TRANSPORTER HZIP4. Eliza- beth Bafaro, Robert Dempski 1021-Pos Board B89 STRUCTURE AND SELF-ASSEMBLY OF ELASTIN-LIKE PEPTIDES: A JOINT MOLECULAR DYNAMICS AND NMR STUDY. Quang Huynh , Sean Reich- held, Sarah Rauscher, Zhen Hao Wu, Simon Sharpe, Régis Pomès 1022-Pos Board B90 A MODEL FOR HYSTERESIS OBSERVED IN PHASE TRANSITIONS OF THER- MALLY RESPONSIVE INTRINSICALLY DISORDERED PROTEIN POLYMERS.  Tyler S. Harmon , Stefan Roberts, Ashutosh Chilkoti, Rohit V. Pappu 1023-Pos Board B91 WALKING THE DNA METHYLATION TIGHTROPE: THE INVOLVEMENT OF INTRINSICALLY DISORDERED REGIONS OF TRANSCRIPTION FAC- TORS. Stephanie M. Bilinovich , Hai Pan, Parminder Kaur, Hong Wang, David C. Williams Jr. 1024-Pos Board B92 MECHANISM UNDERLYING CONFORMATIONAL EFFECTS OF A DISEASE- ASSOCIATED HYDROPHOBIC-TO-HYDROPHOBIC SUBSTITUTION ON AN INTRINSICALLY DISORDERED REGION. Ruchi Lohia , Reza Salari, Grace Board B93 IMPROVING THE PERFORMANCE OF SIMULATIONS OF THE INTRINSI- CALLY DISORDERED N-TERMINAL DOMAIN FROM P53. Nic A. Ezzell , Yue Zhang, Steven T. Whitten, Nicholas C. Fitzkee Brannigan 1025-Pos

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