Biophysical Society 61st Annual Meeting | Program Guide

Voltage-gated Ca Channels II (Boards B265–B275)

Voltage-gated K Channels and Mechanisms of Voltage Sensing and Gating II (Boards B276–B295) 1208-Pos Board B276 USING UNNATURAL AMINO ACIDS TO PROBE THE INTERACTION BE- TWEEN TARANTULA TOXINS AND VOLTAGE SENSING DOMAINS IN K V CHANNELS. Kanchan Gupta , Kenton J. Swartz 1209-Pos Board B277 VOLTAGE DEPENDENCE AND NON-SENSOR RESIDUES.  Joao L. Carvalho-de-Souza , Francisco Bezanilla 1210-Pos Board B278 GENERALIZED INTERACTION ENERGY ANALYSIS OF RESIDUES AT THE VOLTAGE-SENSOR PORE INTERFACE IN THE SHAKER POTASSIUM CHAN- NEL. Ana I. Fernández-Mariño , Kevin Oelstrom, Baron Chanda 1211-Pos Board B279 POLARITY OF THE CHEMICAL ENVIRONMENT SURROUNDING POTASSIUM CHANNEL VOLTAGE SENSORS DETECTED BY SOLVATOCHROMIC DYE-TA- RANTULA TOXIN CONJUGATES. Sebastian Fletcher-Taylor , Mark W. Lillya, Parashar Thapa, Bruce E. Cohen, Jon T. Sack 1212-Pos Board B280 GRAFTING VOLTAGE SENSING SENSITIVITY AND PHARMACOLOGY IN POTASSIUM CHANNELS. Xi Lan, Chunyan Fan, Wei Ji, Fuyun Tian, Tao Xu, Zhaobing Gao 1213-Pos Board B281 LIPID BILAYER PERTURBATION BY THE SNAIL TOXIN 6-BROMO-2-MER- CAPTOTRYPTAMINE DIMER DOES NOT ACCOUNT FOR ITS MODULATION OF VOLTAGE-GATED POTASSIUM CHANNELS. Chris Dockendorff, Disha Gandhi, Ian Kimball, Kenneth S. Eum, Radda Rusinova, Helgi Ingólfsson, Ruchi Kapoor, Thasin Peyear, Stephen F. Martin, Richard W. Aldrich, Olaf S. Andersen, Jon Sack 1214-Pos Board B282 THE ROLE OF K IONS IN OPENING K CHANNELS. Clay M. Armstrong , Toshi Hoshi, Stefan Heinneman 1215-Pos Board B283 A STRUCTURAL MODEL OF THE INACTIVATION GATE OF VOLTAGE ACTI- VATED POTASSIUM CHANNELS. Ariela Vergara-Jaque, Francisco Palma- Cerda, Horacio Poblete, Adam Lowet, Alexander Sukharev, Jeffrey Comer, Miguel Holmgren 1216-Pos Board B284 ANALYSIS OF THE STATE-DEPENDENT BLOCK OF SHAKER IR BY BTBUA. Ti- bor G. Szanto, Jeffrey D. Fineberg, Manuel Covarrubias, Zoltan Varga, Gyorgy Panyi 1217-Pos Board B285 THE ACTIVATION GATE AND THE SELECTIVITY FILTER OF KCSA ARE TIGHTLY COUPLED. Cholpon Tilegenova, D. Marien Cortes, Luis G. Cuello 1218-Pos Board B286 STRUCTURAL DYNAMICS OF THE POTASSIUM CHANNEL SELECTIVITY FILTER REVEALED BY SINGLE-MOLECULE FRET. Shizhen Wang , Colin G. Nichols 1219-Pos Board B287 PROBING THE GATING OF KV10.1 CHANNELS BY MTS REAGENTS. Adam P. Tomczak, Ferenc Papp, Florina Zakany, Pal Pap, Luis A. Pardo, Gyorgy Panyi, Zoltan Varga 1220-Pos Board B288 THE EAG DOMAIN MEDIATES THE RESPONSE OF HEAG1 K + CHANNELS TO BOTH VOLTAGE AND CA 2+- CALMODULIN. Alina Finch , Éva Lörinczi, Mat- thew Helliwell, John Mitcheson

M O N D A Y

1197-Pos

Board B265

STIMULATION OF AT 1 1.2 L-TYPE CA 2+ CHANNELS THROUGH BETA-ARRESTIN2 AND CASEIN KINASE 2 IN IMMATURE CARDIOMYOCYTES. Toshihide Kashihara 1198-Pos Board B266 MANIPULATING L-TYPE CALCIUM CHANNEL ACTIVITY ALTERS MITO- CHONDRIAL FUNCTION AND PREVENTS HYPERTROPHIC CARDIOMYOPA- THY IN A TROPONIN I MUTANT MOUSE MODEL. Helena M. Viola , Victoria P.A. Johnstone, Christopher Semsarian, Livia C. Hool 1199-Pos Board B267 STABLE INTERACTION BETWEEN VOLTAGE-ACTIVATED CA 2+ CHANNEL Α1 AND Β SUBUNITS REVEALED BY TRANSLOCATABLE Β SYSTEMS. Jun-Hee Yeon, Byung-Chang Suh 1200-Pos Board B268 DELETION OF Α 2 Δ-1 CALCIUM CHANNEL SUBUNIT REDUCES CALCIUM INFLUX AND ALTERS THE ELECTRICAL ACTIVITY OF MOUSE CHROMAFFIN CELLS. Matteo M. Ottaviani, Vincenzo Mastrolia, Laura Guarina, Emilio Carbone, Petronel Tuluc 1201-Pos Board B269 International Travel Awardee INVESTIGATION OF THE PROTEOLYTIC CLEAVAGE OF Α 2 Δ SUBUNITS: A MECHANISTIC SWITCH FROM NHIBITION TO ACTIVATION OF VOLTAGE- GATED CALCIUM CHANNELS?  Ivan Kadurin , Simon Rothwell, Laurent Ferron, Otto Meyer, Annette Dolphin 1202-Pos Board B270 HYDROGEN PEROXIDE INHIBITS WHOLE-CELL I CA,L BUT INCREASES ON- CELL I CA,L AND EBSELEN, AN ORGANOSELENIUM COMPOUND, SUP- PRESSES I CA,L IN ARTERIAL SMOOTH MUSCLE CELLS. Rikuo Ochi , Sukrutha Chettimada, Sachin A. Gupte 1203-Pos Board B271 OPTICALLY PROBING THE MECHANISM OF VOLTAGE-DEPENDENT FACILI- TATION IN CA V 1.2 CHANNELS. Antonios Pantazis , Daniel Sigg, Alan Neely, Riccardo Olcese 1204-Pos Board B272 TREATMENT OF ADULT MDX MICE WITH PHOSPHORODIAMIDATE MOR- PHOLINO OLIGOMER RESTORES CARDIAC MITOCHONDRIAL ENERGETICS AND PREVENTS THE DYSTROPHIC CARDIOMYOPATHY. Helena M. Viola , Victoria P. A. Johnstone, Abbie M. Adams, Susan Fletcher, Livia C. Hool 1205-Pos Board B273 STAC PROTEINS SUPPRESS CALCIUM DEPENDENT INACTIVATION OF NEURONAL L-TYPE CA 2+ CHANNELS. Alexander Polster , Stefano Perni, Kurt G. Beam 1206-Pos Board B274 ANGIOTENSIN II STIMULATES L-TYPE CALCIUM CURRENT IN MOUSE ATRIAL MYOCYTES BY AFFECTING CAVEOLAE-HOUSED CHANNELS. Marina Balycheva , Timothy J. Kamp, Alexey Glukhov 1207-Pos Board B275 STAC3 FACILITATED EXPRESSION OF CA V 1.1 IN XENOPUS OOCYTES TO ASSESS FUNCTIONAL CONSEQUENCES OF HYPOPP MUTANT CA V 1.1- R528H. Fenfen Wu, Steve C. Cannon ANGIOTENSIN RECEPTORS ACTIVATES CA V

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