Biophysical Society 61st Annual Meeting | Program Guide

1286-Pos Board B354 MAGNETIC CYTOSKELETON AFFINITY (MICA) PURIFICATION FOR FAST PURIFICATION OF CARGO-ATTACHED MOLECULAR MOTORS. Marco Tjioe , Hyeon Ryoo, Pinghua Ge, Yuji Ishitsuka, Kevin Teng, Paul Selvin 1287-Pos Board B355 TURNING AROUND AT THE TIP: SINGLE-MOLECULE DYNAMICS OF IN- TRAFLAGELLAR TRANSPORT IN C. ELEGANS CHEMOSENSORY CILIA. Jona Mijalkovic, Jaap van Krugten, Felix Oswald, Seyda Acar, Erwin J. Peterman 1288-Pos Board B356 Education Travel Awardee THE ROLE OF THE COVER-NECK BUNDLE IN MULTI-MOTOR TRANSPORT AGAINST LOAD IN CELLS. Breane G. Budaitis , Kristin I. Schimert, Guido Scarabelli, Barry J. Grant, Kristen J. Verhey 1289-Pos Board B357 MODELING CARGO TRANSPORT BY PAIRS OF KINESIN-1 AND -3 MO- TORS. Goker Arpag , Stephen Norris, Kristen Verhey, William O. Hancock, Erkan Tuzel 1290-Pos Board B358 Education Travel Awardee ENGINEERING INHIBITABLE KINESIN-3 MOTORS BY A NOVEL CHEMICAL- GENETIC APPROACH. Shirley Chen , T. Lynne Blasius, Martin F. Engelke, Kristen J. Verhey Myosins (Boards B359–B378) 1291-Pos Board B359 MOLECULAR MECHANISM OF SYNCHRONOUS FORCE GENERATIONS AMONG MYOSIN MOLECULES. Motoshi Kaya, Takumi Washio, Hideo Higuchi 1292-Pos Board B360 O-MYO! AN O-SHAPED MYOSIN GLIDING ASSAY FOR CHARACTERIZING LONG-TERM ACTIN-MYOSIN BEHAVIORS . Rizal F. Hariadi , Abhinav J. Appukutty, Sivaraj Sivaramakrishnan 1293-Pos Board B361 CHANGES IN MYOSIN CROSSBRIDGE CYCLE DURING HUMAN DEVELOP- MENT. Alice Ward Racca , Samantha Lynn, Michael A. Geeves 1294-Pos Board B362 International Travel Awardee A NEW HUMANIZED MOUSE MODEL FOR STUDYING INHERITED CAR- DIOMYOPATHIC MUTATIONS IN THE MYH7 GENE. Farah Haque , Mohsen Sarikhani, Souhrid Mukherjee, N. Ravi Sundaresan, John A. Mercer 1295-Pos Board B363 A R146N HYPERTROPHIC CARDIOMYOPATHY MYOSIN MUTATION DIS- RUPTS MYOSIN FUNCTION, MYOFIBRILLAR STRUCTURE, AND CARDIAC CONTRACTION IN DROSOPHILA . Adriana S. Trujillo , William A. Kronert, Kaylyn Bell, Meera C. Viswanathan, Girish C. Melkani, Anju Melkani, Anthony Cammarato, Douglas M. Swank, Sanford I. Bernstein 1296-Pos Board B364 KINETIC CHARACTERIZATION OF THE MITOCHONDRIAL TRANSPORTER HUMAN MYOSIN XIX. Matt Mcconnell, Laura Jackson, Ailian Xiong, Betty Belknap, Howard White, Omar Quintero, Eva Forgacs 1297-Pos Board B365 SINGLE MOLECULE CHARACTERISATION OF THE MOLECULAR MOTOR MYOSIN VB. Lucia Gardini, Sarah M. Heissler, Claudia Arbore, James R. Sellers, Francesco S. Pavone, Marco Capitanio 1298-Pos Board B366 DIRECT SINGLE MOLECULE OBSERVATIONS OF THE UNIQUE MECHANICAL STATE OF HUMAN MYOSIN-6. Yasuharu Takagi , Nikolas Hundt, Neil Bil- lington, Joanna Andrecka, Daniel Cole, Adam J. Fineberg, Noriko Katagiri, Jonathan E. Bird, Thomas B. Friedman, Philipp Kukura, James R. Sellers

1273-Pos Board B341 TROPOMYOSIN FLUCTUATIONS OVER A MULTI-WELL ENERGY LAND- SCAPE: A BROWNIAN RATCHET MODEL OF CARDIAC MUSCLE CONTRAC- TION. Yasser Aboelkassem , Natalia Trayanova 1274-Pos Board B342 INVESTIGATING THE PHENOTYPE OF CARDIOMYOPATHY-ASSOCIATED ALPHA-TROPOMYOSIN E192K MUTATION IN PATIENT-DERIVED ENGI- NEERED HEART TISSUE. Lorenzo R. Sewanan , Jinkyu Park, Yongming Ren, Angela Urdaneta, Michael Rynkiewicz, Jeffrey Moore, William Lehman, Daniel L. Jacoby, Yibing Qyang, Stuart G. Campbell

M O N D A Y

Kinesins, Dyneins, and Other Microtubule-based Motors I (Boards B343–B358)

1275-Pos Board B343 RECONSTITUTION OF EUKARYOTIC FLAGELLAR AXONEMES BY THE BOTTOM-UP STRATEGY. Misaki Shiraga, Junya Kirima, Hiroaki Kojima, Kazuhiro Oiwa 1276-Pos Board B344 THE COORDINATION AND REGULATION OF AXONEMAL DYNEIN.  Joshua Alper 1277-Pos Board B345 REGULATION OF DYNEIN-DRIVEN MOTILITY BY HOOK PROTEINS. Mara Olenick , Mariko Tokito, Malgorzata Boczkowska, Roberto Dominguez, Erika Holzbaur 1278-Pos Board B346 THREE-DIMENSIONAL SNAPSHOTS OF THE MICROTUBULE-BOUND DYNEIN-DYNACTIN COMPLEX. Danielle Grotjahn , Saikat Chowdhury, Yiru Xu, Gabriel Lander 1279-Pos Board B347 REGULATING NATIVE CYTOPLASMIC DYNEIN’S PROCESSIVITY. Vincent Behrens , Tim Scholz, Bernhard Brenner, Michael A. Geeves, Walter Stef- fen 1280-Pos Board B348 TRACKING DYNEIN STEPPING ALONG MICROTUBULES USING MULTI- COLOR HIGH RESOLUTION IMAGING. Stefan Niekamp , Nico Stuurman, Nan Zhang, Ronald D. Vale 1281-Pos Board B349 A DYNAMIC MODEL FOR THE PROCESSIVE MOTION OF DYNEIN ON MI- CROTUBULES. Ya-chang Chou 1282-Pos Board B350 MULTI-SCALE INVESTIGATION ON THE MECHANISMS OF DYNEINS’ MO- TION ON MICROTUBULE. Lin Li , Jushua Alper, Emil Alexov 1283-Pos Board B351 TAU DIRECTS TRANSPORT ALONG MICROTUBULES THROUGH DIFFER- ENTIAL REGULATION OF KINESIN AND DYNEIN. Abdullah R. Chaudhary , Adam G. Hendricks 1284-Pos Board B352 ENSEMBLE MICROSCOPY REVEALS NANOSCALE PATTERNS OF MOLECU- LAR MOTORS ON MICROTUBULES. Louis Reese , Marian Baclayon, Nùria Taberner Carretero, Maurits Kok, Roland Dries, Esengül Yildirim, Andrea Martorana, Martin Depken, Marileen Dogterom 1285-Pos Board B353 MECHANISMS UNDERLYING THE NUCLEATION AND KINESIN-DRIVEN AS- SEMBLY OF MICROTUBULE RINGS. George D. Bachand , Virginia VanDe- linder, Christina Ting, Stephanie Brener

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