Biophysical Society 61st Annual Meeting | Program Guide

1539-Plat 9:45 am SPATIAL ORGANIZATION OF NUCLEAR STRUCTURES BY DUAL COLOUR SUPER-RESOLUTION MICROSCOPY. Maria J. Sarmento , Lorenzo Scipioni, Melody Di Bona, Mario Faretta, Laura Furia, Gaetano I. Dellino, Pier G. Pelicci, Paolo Bianchini, Alberto Diaspro, Luca Lanzanò 1540-Plat 10:00 am TIME-RESOLVED SINGLE CELL, SUB-CELLULAR COMPARTMENTALIZED PROTEOMICS, COMBINING PRECISE MICROFLUIDICS, DECONVOLUTION AND ULTRASENSITIVE SINGLE-MOLECULE MICROSCOPY.  Adam J. M. Wollman , Sviatlana Shashkova, Niek Welkenhuysen, Erik G. Hedlund, Stefan Hohmann, Mark C` Leake Platform Protein-Nucleic Acid Interactions II 8:15 am - 10:15 am, Room R08/09 Co-Chairs Ioulia Rouzina, University of Minnesota Vladimir Mekler, Rutgers University 1541-Plat 8:15 am GENOMIC RNA BINDING PROMOTES RETROVIRAL GAG PROTEIN INTER- ACTIONS IN AN ASSEMBLY-COMPETENT CONFORMATION LEADING TO SELECTIVE GENOME PACKAGING.  Ioulia Rouzina , Shuohui Liu, Erik D. Olson, Tiffiny Rye-McCurdy, Christiana Binkley, Joshua-Paolo Reyes, Leslie J. Parent, Karin Musier-Forsyth 1542-Plat 8:30 am KINETICS OF DCAS9 TARGET SEARCH IN ESCHERICHIA COLI.  Daniel Jones , Cecilia Unoson, Prune Leroy, Vladimir Curic, Johan Elf 1543-Plat 8:45 am ARGONAUTE TARGET SEARCH IS FACILITATED BY LONG DISTANCE DIF- FUSION.  Tao Ju Cui , Stanley D Chandradoss, Jorrit Hegge, John van der Oost, Chirlmin Joo 1544-Plat 9:00 am HOW CONFORMATIONAL DYNAMICS INFLUENCES THE PROTEIN SEARCH FOR TARGETS ON DNA. Maria P. Kochugaeva , Alexey A. Shvets, Anatoly B. Kolomeisky 1545-Plat 9:15 am SPLICEOSOMAL U1A PROTEIN-SL2 RNA BINDING AFFINITY DECREASES IN CELLS.  Caitlin Davis , Irisbel Guzman, David Gnutt, Martin Gruebele 1546-Plat 9:30 am VISUALIZING INFECTION INITIATION OF BACTERIOPHAGE P22 BY CRYO- ELECTRON TOMOGRAPHY.  Chunyan Wang , Jiagang Tu, Bo Hu, Ian Molineux, Jun Liu 1547-Plat 9:45 am USING SITE SPECIFIC FLUORESCENT PROBES TO EXAMINE REPLICATION FORK DESTABILIZATION BY REGULATORY PROTEINS OF THE BACTERIO- PHAGE T4 DNA REPLICATION COMPLEX.  Davis Jose , Miya Mary Michael, Wonbae Lee, Thomas H. Steinberg, Andrew H. Marcus, Peter H. von Hippel 1548-Plat 10:00 am MECHANISM OF DUPLEX DNA DESTABILIZATION BY RNA-GUIDED CAS9 NUCLEASE DURING DNA INTERROGATION.  Vladimir Mekler , Leonid Minakhin, Konstantin Severinov

1528-Plat 9:00 am MECHANOSENSETIVE ATP RELEASE INVOLVES A NON-CONDUCTIVE PATH- WAY: EVIDENCE FROM LARGE FIELD OF VIEW REAL-TIME IMAGING.  Olga Ponomarchuk , Francis Boudreault, Sergei N. Orlov, Ryszard Grygorczyk 1529-Plat 9:15 am THE SHORT TERM RESPONSE OF PECAM-1 TO MECHANICAL LOADING: CYCLOOXYGENASE-2 AND NITRIC OXIDE PRODUCTION WITH AFM PULL- ING AND SHEAR STRESS.  Anne Marie T. Weber , Rick Mathews, Zahin Haq, Limary M. Cancel, John M. Tarbell 1530-Plat 9:30 am MECHANICALLY-INDUCED GATING IN PKD2L1 (TRPP2): CALCIUM-IN- DUCED ACTIVATION MASQUERADING AS FORCE SENSITIVITY?  Charles D. Cox , Chai Ann Ng, Navid Bavi, Boris Martinac 1531-Plat 9:45 am MICROGRAVITY MODULATES DRUG-INDUCED ENHANCEMENT OF CANCER CELL MIGRATION.  Devika Prasanth, Sindhuja Suresh, Michael Mimlitz, Noah Zetocha, Andrew E. Ekpenyong 1532-Plat 10:00 am TREK-2 HAS AN ASYMMETRICAL RESPONSE TO FORCE CHANGES IN THE MEMBRANE. Michael Voldsgaard Clausen , Viwan Jarerattanachat, Jackie Ang, Liz Carpenter, Stephen Tucker Platform Optical Microscopy and Super-Resolution Imaging: Applications to Cellular Molecules 8:15 am - 10:15 am, Room R06/07 Co-Chairs AdamWollman, University of York, United Kingdom Linda Kenney, University of Illinois, Chicago 1533-Plat 8:15 am ILLUMINATING BACTERIAL ELECTROPHYSIOLOGY.  Giancarlo N. Bruni , Benjamin Dodd, Joel Kralj 1534-Plat 8:30 am UNDERSTANDING THE ASYMMETRIC MIPZ GRADIENT IN CAULOBACTER CRESCENTUS . Matthew D. Stilwell , Nikolai P. Radzinski, James C. Weis- shaar, Douglas B. Weibel 1535-Plat 8:45 am A NOVEL DNA BINDING MODE OF H-NS DRIVES CHROMOSOME COM- PACTION AND GENE SILENCING IN SINGLE BACTERIAL CELLS.  Linda J. Kenney 1536-Plat 9:00 am INVESTIGATING RNAP SEARCH DYNAMICS IN LIVE E. COLI CELLS USING SINGLE MOLECULE AND STATISTICAL METHODS.  Kelsey Bettridge , Chris Bohrer, Jie Xiao 1537-Plat 9:15 am COLLECTIVE LIVE-CELL SUPERRESOLVED TRACES REVEAL NONAXONOMAL DYNAMICS OF INTRAFLAGELLAR TRANSPORT PARTICLES AT THE CILIARY BASE.  Tony Yang , Nguyet Thi Minh Tran, Weng Man Chong, Jung-Chi Liao 1538-Plat 9:30 am REAL-TIME SUBCELLULAR LOCALIZATION REVEALS HIDDEN INTRAFLA- GELLAR TRANSPORT MECHANISMS.  Anthony Kovacs, Jonathan Kessler, Je-Luen Li, HuaWen Lin, Susan Dutcher, Yan Mei Wang

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