Biophysical Society 62nd Annual Meeting | Program Guide

1956-Plat 5:45 pm MECHANISM OF REGULATION OF GI/O-MEDIATED TRPC4 ACTIVATION BY INTRACELLULAR PROTONS.  Qiaochu Wang , Dhananjay P. Thakur, Jinbin Tian, Jaepyo Jeon, Michael X. Zhu Platform Protein Dynamics and Allostery II 4:00 pm–6:00 pm, Esplanade, Room 156 Co-Chairs Toshiko Ichiye, Georgetown University Denis Schmidt, Heinrich Heine University Düsseldorf, Germany 1957-Plat 4:00 pm IDENTIFYING CAUSALITY IN MUTANT KRAS RESIDUE PAIRS FROMMO- LECULAR DYNAMICS DATA ANALYSIS.  Sezen Vatansever , Burak Erman, Zeynep H. Gumus 1958-Plat 4:15 pm PROTEIN HYDRAULICS: WATER MEDIATED COOPERATIVITY OF SUBSTRATE BINDING IN PKA.  Piotr Setny 1959-Plat 4:30 pm AN ALLOSTERIC REGION OF SRC TYROSINE KINASE ALLOWS FOR STABI- LIZATION OF ITS ACTIVE-LIKE CONFORMATION.  Lalima G Ahuja , Yilin Meng, Alexandr P Kornev, Benoit Roux, Susan Taylor 1960-Plat 4:45 pm DIRECT OBSERVATION OF GDP UNBINDING REVEALS MULTIPLE AL- LOSTERIC PATHWAYS UNDERLIE G-PROTEIN ACTIVATION.  Sukrit Singh , Xianqiang Sun, Kendall J. Blumer, Gregory R. Bowman 1961-Plat 5:00 pm CONFORMATIONAL DYNAMICS OF HISTONE METHYLTRANSFERASE SET8 PROBED BY MILLISECOND-TIMESCALE MOLECULAR DYNAMICS, MARKOV STATE MODELING AND BIOCHEMICAL EXPERIMENTS.  Rafal P. Wiewiora , Shi Chen, Minkui Luo, John D. Chodera 1962-Plat 5:15 pm HOW COLLAGEN FIBRILS DYNAMICALLY DISTRIBUTE AND MEASURE STRESSES.  Agnieszka Obarska-Kosinska , Christopher Zapp, Frauke Gräter 1963-Plat 5:30 pm Education Travel Awardee INVESTIGATING CHEMOKINE RECEPTOR CCR2 DYNAMICS AND DRUG- GABILITY BY ENSEMBLE BASED APPROACHES.  Bryn C. Taylor , Irina Kufareva, Tracy Handel, Rommie E. Amaro 1964-Plat 5:45 pm MHC CLASS II COMPLEXES SAMPLE INTERMEDIATE STATES ALONG THE ANTIGENIC PEPTIDE EXCHANGE PATHWAY.  Sebastian Stolzenberg , Marek Wieczorek, Jana Sticht, Sebastian Günther, Christoph Wehmeyer, Zeina El Habre, Miguel Álvaro-Benito, Frank Noé, Christian Freund Dinner Meet-Ups 5:30 pm – 5:45 pm, South Lobby, Society Booth Interested in making new acquaintances and experiencing the cuisine of San Francisco? Meet at the Society Booth each evening, Sunday through Tuesday, at 5:30 pm where a BPS member will coordinate dinner at a local restaurant. Publications Committee Meeting 6:00 pm–10:00 pm, Marriott Marquis, Pacific A

1944-Plat 4:45 pm COMBINATORIAL ORIGIN OF PROTEIN EXPRESSION NOISE.  Sangjin Kim , Christine Jacobs-Wagner 1945-Plat 5:00 pm THE INTERACTION BETWEEN BACTERIOPHAGE T7 DNA POLYMERASE AND GENE 2.5 PROTEIN AT THE SINGLE-MOLECULE LEVEL.  Julia Bakx , Jordi Cabanas-Danes, Erwin J.G. Peterman, Gijs J.L. Wuite 1946-Plat 5:15 pm ANISOTROPIC FLUCTUATIONS IN THE RIBOSOME DETERMINE AA-TRNA KINETICS.  Huan Yang , Jeffrey Noel, Paul Charles Whitford 1947-Plat 5:30 pm MECHANISTIC INSIGHT INTO THE INITIATION OF REPEAT-ASSOCIATED NONAUG TRANSLATION.  Rosslyn Grosely , Joseph Puglisi 1948-Plat 5:45 pm EVOLUTIONARILY-ENCODED TRANSLATION KINETICS COORDINATE CO- TRANSLATIONAL SSB CHAPERONE BINDING IN YEAST.  Nabeel Ahmed , Kristina Döring, Günter Kramer, Bernd Bukau, Edward P. O’Brien Platform TRP Channels 4:00 pm–6:00 pm, Esplanade, Room 155 Co-Chairs Eleonora Gianti, Temple University Eleonora Zakharian, University of Illinois 1949-Plat 4:00 pm MOLECULAR INSIGHTS INTO TRPV1 POLYMODAL ACTIVATION: IS AL- LOSTERIC COUPLING BETWEEN THE TOXIN AND THE VANILLOID BINDING SITES MEDIATED BY ANNULAR LIPIDS?  Eleonora Gianti , Michael Klein, Tibor Rohács, Vincenzo Carnevale 1950-Plat 4:15 pm THE ROLE OF THE SELECTIVITY FILTER IN TRPV1 CHANNEL GATING.  Andres Jara-Oseguera , Kenton J. Swartz 1951-Plat 4:30 pm OXYTOCIN MODULATES NOCICEPTION AS A DIRECT AGONIST OF PAIN- SENSING TRPV1.  Yelena Nersesyan, Lusine Demirkhanyan, Deny Cabezas- Bratesco, Victoria Oakes, Ricardo Kusuda, Tyler Dawson, Xiaohui Sun, Chike Cao, Alejandro Cohen, Katharina Zimmermann, Carmen Domene, Sebastian Brauchi, Eleonora Zakharian 1952-Plat 4:45 pm MECHANISM OF TRPV5 MODULATION AND GATING AS REVEALED BY CRYO-EM.  Taylor E. T. Hughes , David Lodowski, Kevin Huynh, Aysenur Yazici, John del Rosario, Abhijeet Kapoor, Sandip Basak, amrita Samanta, Sudha Chakrapani, Z. Hong Zhou, Marta Filizola, Tibor Rohacs, Seungil Han, Vera Moiseenkova-Bell 1953-Plat 5:00 pm STRUCTURES OF THE ENDOLYSOSOMAL TRPML3 CHANNEL IN DISTINCT STATES REVEAL ACTIVATION AND REGULATION MECHANISMS. Minghui Li, Xiaoyuan Zhou, Deyuan Su, Qi Jia, Huan Li, Xueming Li, Jian Yang 1954-Plat 5:15 pm RESIDUES AT TRPA1 S4-S5 LINKER N-TERMINUS ARE CRITICAL FOR TRANSLATING COVALENT MODIFICATION TO CHANNEL ACTIVATION.  Wei Chou Tseng , Karen Padilla, Seungil Han, Aaron Gerlach 1955-Plat 5:30 pm A PIP 2 BINDING SITE ON A HUMAN TRP CHANNEL: SIMULATION STUDIES OF PKD2.  Qinrui Wang , George Hedger, Prafulla Aryal, Jiye Shi, Elizabeth P. Carpenter, Mark S. P. Sansom

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