Biophysical Society 62nd Annual Meeting | Program Guide

2027-Pos Board B43 ENGINEERING A PROMISCUOUS ACETYLTRANSFERASE.  Jenna Morris , Yadilette Rivera-Colón 2028-Pos Board B44 ENGENDERING METHANE MONOOXYGENASE AND HYDROGEN PEROX- IDE OXIDASE ACTIVITY INTO A DESIGNED DIMETAL PROTEIN BY INCREAS- ING PROTEIN DYNAMICS. Ronald L. Koder , Jonathan M. Preston, Bernard H. Everson, Emma Bjerkefeldt, Florika C. Macazo, Fabien Giroud, Shelly D. Minteer, David J. Vinyard, Gary W. Brudvig 2029-Pos Board B45 A MULTI-SCALE APPROACH TO THE STUDY OF PROTEIN DESIGN, FOLD- ING AND AGGREGATION. Francesca Nerattini, Valentino Bianco, Chiara Cardelli, Luca Tubiana, Ivan Coluzza 2030-Pos Board B46 MONITOR AND CONTROL UPSTREAM BIOPROCESSING USING A POINT- OF-NEED MASS SPECTROMETER. Richard W. Moseley , Alexander I. Board B47 PEBANK: A COMPREHENSIVE DATABASE FOR PROTEIN ENGINEERING AND DESIGN. Connie Wang , Paul Chang, Marie Ary, Stephen Mayo, Barry Olafson 2032-Pos Board B48 A KNOB-SOCKET BASED RULE SET FOR DESIGNING PEPTIDE BINDING TO PDZ DOMAINS. Shivarni Patel , Hyun Joo, Jerry Tsai Protein Stability, Folding, and Chaperones II (Boards B49–B67) 2033-Pos Board B49 QUANTITATIVE PREDICTION OF BACTERIAL FITNESS FROM A PROTEIN’S ENERGY LANDSCAPE. Catherine R. Knoverek , Kathryn M. Hart, Gregory R. Bowman 2034-Pos Board B50 PREDICTION OF NEW STABILIZING MUTATIONS BASED ON MECHANIS- TIC INSIGHTS FROMMARKOV STATE MODELS. Maxwell I. Zimmerman , Kathryn M. Hart, Carrie A. Sibbald, Thomas E. Frederick, John R. Jimah, Catherine R. Knoverek, Niraj H. Tolia, Gregory R. Bowman 2035-Pos Board B51 PROBING PROTEIN FOLDING LANDSCAPE BY USING COMBINED FORCE SPECTROSCOPY AND MOLECULAR DYNAMICS SIMULATIONS.  Ha H. Truong , Susan Marqusee 2036-Pos Board B52 THE STRUCTURAL BASIS OF THERMOSTABILITY IN AN ENGINEERED VARI- ANT OF THE ENGRAILED HOMEODOMAIN.  Jennifer T. Young , Catrina Nguyen, Michelle E. McCully 2037-Pos Board B53 CHEMICAL CHAPERONE ACTIVITY OF NAD + IN PROTEIN FOLDING. Chen Chen, Pei-Fen Liu, Chiwook Park 2038-Pos Board B54 THE INFLUENCE OF THE APICAL DOMAIN OF GROEL CHAPERONE ON THE KINETICS AND THERMODYNAMICS OF ZEBRAFISH DIHYDROFOLATE RE- DUCTASE UNDER THERMAL STRESS. Charu Thapliyal , Pratima Chaudhuri, Tapan K. Chaudhuri 2039-Pos Board B55 NANOMECHANICS OF PROTEIN UNFOLDING OUTSIDE PROTEASE NANO- PORES. Binquan Luan McIntosh 2031-Pos

2013-Pos Board B29 EXPERIMENTAL AND COMPUTATIONAL STUDIES OF OBSCURIN’S FLEXIBIL- ITY.  Jake Whitley , Daniel Marzolf, Oleksandr Kokhan, Nathan Wright Protein Structure, Prediction, and Design I (Boards B30–B48) 2014-Pos Board B30 CID Travel Awardee ANALYSIS OF RELATIVE BINDING AFFINITY PREDICTIONS FOR PROTEIN- PROTEIN COMPLEXES. Xavier Bonner , Brian Kuhlman, Hayretin Yu- merefendi 2015-Pos Board B31 MOLECULAR DESIGN OF ARTIFICIAL RING FINGERS FOR DETECTING UBIQUITINATION ACTIVITIES. Kazuhide Miyamoto , Ayumi Yamashita, Kazuki Saito 2016-Pos Board B32 RATIONAL ENGINEERING AND ROSETTA DESIGN OF A GENETICALLY ENCODED FLUORESCENT REPORTER OF PROTEIN CONFORMATIONAL CHANGE.  Jan Maly , Yann Thillier, Grace Or, Kit Lam, Jon T. Sack, Lin Tian, Vladimir Yarov-Yarovoy 2017-Pos Board B33 SUCCESSFUL RATIONAL AFFINITY MATURATION OF AN ALPHA-SYNUCLEIN ANTIBODY. Sai Pooja Mahajan , Bunyarit Meksiriporn, Dujduan Waraho- Zhmayev, Fernando Escobedo, Matthew P. Delisa 2018-Pos Board B34 THE DYNAMIC SELF-REGULATION OF MODULAR CULLIN-RING LIGAS- ES. Ryan Lumpkin , Elizabeth Komives 2019-Pos Board B35 IDENTIFICATION OF A SCHIFF BASE ADDUCT IN CYP3A4. Parker Flanders , Matthew Schwartz, Justice Spriggs, Tom Larson, Larry R. Masterson 2020-Pos Board B36 DESIGNING SELECTIVE PROTEIN BINDING SITES. Francesca Nerattini , Luca Tubiana, Chiara Cardelli, Valentino Bianco, Christoph Dellago, Ivan Coluzza 2021-Pos Board B37 ARE PROTEINS SUCH UNIQUE POLYMERS?–THE ROLE OF DIRECTIONAL INTERACTIONS IN THE DESIGNABILITY OF GENERALIZED HETEROPOLY- MERS. Chiara Cardelli , Valentino Bianco, Lorenzo Rovigatti, Francesca Nerattini, Luca Tubiana, Christoph Dellago, Ivan Coluzza 2022-Pos Board B38 RATIONAL DESIGN OF PDZ DOMAIN SPECIFICITY. Young Joo Sun , Titus Hou, Lokesh Gakhar, Sahezeel Awadia, Rafael Garcia-Mata, Ernesto Fuentes 2023-Pos Board B39 GLASS CHIP FOR NANOPORE BASED LOW NOISE RESISTIVE PULSE SENS- ING. Lennart J. de Vreede , Cuifeng Ying, Michael Mayer 2024-Pos Board B40 DE NOVO DESIGN OF CROSS-Α amYLOID-LIKE FIBRILS WITH CELLULAR ACTIVITY. Shao-Qing Zhang , Lijun Liu, Junjiao Yang, Marco Lolicato, Huong Kratochvil, Xiaokun Shu, William F. DeGrado 2025-Pos Board B41 RATIONAL PROTEIN DESIGN VIA STRUCTURE-ENERGETICS-FUNCTION RELATIONSHIPS IN THE PHOTOACTIVE YELLOW PROTEIN (PYP) MODEL SYSTEM.  Johan H. Both , Robert M. Parrish, Todd J. Martínez, Steven G. Boxer 2026-Pos Board B42 Education Travel Awardee STRUCTURAL DESIGN OF NOVEL PROTEIN ACETYLTRANSFERASES.  Logan Kaler , Yadilette Rivera-Colón

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