Biophysical Society 62nd Annual Meeting | Program Guide

2154-Pos Board B170 BENCHMARKING RNA FORCE FIELDS USING HAIRPIN LOOP FOLDING FREE ENERGY CHANGE. Louis G. Smith , Zhen Tan, Aleksandar Spasic, Alan Grossfield, David H. Mathews 2155-Pos Board B171 ENHANCED SAMPLING OF LNCRNA CONFORMATIONAL SPACE FOR DE- FINING ENSEMBLES OF STRUCTURES USED IN ENSEMBLE DOCKING AND VIRTUAL SCREENING OF RNA-FOCUSED SMALL MOLECULES. Michael Yonkunas , Nathan Baird 2156-Pos Board B172 CHARACTERIZING THE FOLDING AND MISFOLDING OF THE AQUIFEX AEOLICUS TMRNA FRAMESHIFTING PSEUDOKNOT VIA MASSIVELY PAR- ALLEL MOLECULAR DYNAMICS SIMULATIONS. Xavier Martinez 2157-Pos Board B173 MESO-SCALE MODELING FOR PREDICTING PROPERTIES OF RNA COM- PLEXES. Eckart Bindewald , Mathias Viard, Bruce A. Shapiro 2158-Pos Board B174 IN-SILICO, IN-VITRO, AND IN-VIVO STUDIES OF SIRNA DELIVERY USING CATIONIC BOLAAMPHIPHILE VESICLES. Taejin Kim , Kirill Afonin, Mathias Viard, Eliahu Heldman, Bruce Shapiro 2159-Pos Board B175 AN EFFECTIVE SCORING FUNCTION FOR RNA-RNA INTERACTIONS DE- RIVED WITH A DOUBLE-ITERATIVE METHOD. Yumeng Yan, Zeyu Wen, Di Zhang, Jiahua He, Shengyou Huang 2160-Pos Board B176 RNA STRUCTURE PREDICTION GUIDED BY COEVOLUTIONARY INFORMA- TION. Mehari Bayou Zerihun , Alexander Schug 2161-Pos Board B177 HELIX-BASED RNA TWO-DIMENSIONAL STRUCTURE PREDICTION. Fengfei Wang, Xiaojun Xu 2162-Pos Board B178 MARTINI COARSE-GRAINED FORCE FIELD FOR RNA. Jaakko J Uusitalo, Helgi I Ingólfsson, Siewert J Marrink, Ignacio Faustino 2163-Pos Board B179 AUTOMATED FORCE-FIELD PARAMETRIZATION GUIDED BY MULTISYSTEM ENSEMBLE AVERAGES. Andrea Cesari , Sandro Bottaro, Giovanni Bussi 2164-Pos Board B180 TOPOLOGICAL CONSTRAINTS AND THEIR CONFORMATIONAL ENTROPIC PENALTIES ON RNA FOLDS. Ethan N.H. Phan , Chi H. Mak 2165-Pos Board B181 EXAGGERATED SWIVEL MOTIONS OF THE SMALL SUBUNIT HEAD DOMAIN ARE REQUIRED FOR TRNA TRANSLOCATION THROUGH THE BACTERIAL RIBOSOME. Wataru Nishima, Scott C. Blanchard, Karissa Y. Sanbonmatsu 2166-Pos Board B182 A MULTI-COLOR RIBOSWITCH-BASED PLATFORM FOR IMAGING OF MRNA AND SMALL NON-CODING RNA IN LIVE MAMMALIAN CELLS.  Esther Braselmann , Aleksandra Wierzba, Jacob T. Polaski, Mikołaj Chromiński, Dilara Batan, Dorota Gryko, Robert T. Batey, amy Palmer 2167-Pos Board B183 SUBNANOMETER CRYO-EM STRUCTURE OF T-BOX AND TRNA COM- PLEX. Zhaoming Su 2168-Pos Board B184 PROBING MECHANICAL PROPERTIES OF BIOMOLECULES USING NANO- PORES. Prasad Bandarkar , Huan Yang, Robert Henley, Pradeep Waduge, Meni Wanunu, Paul C. Whitford

2169-Pos Board B185 ORNITHINE DECARBOXYLASE ANTIZYME PSEUDOKNOT RNA BINDING TO SPERMINE REGULATES GENE EXPRESSION.  Juliane Strauss-Soukup , Jodi Monahan, Katie Del Vecchio, Molly McDevitt, Zachariah Holmes, Saman- tha Stoupa, Garrett Soukup 2170-Pos Board B186 SELECTED POLYCATIONIC SURFACTANTS AS SIRNA CARRIERS FOR GENE THERAPY. Weronika J. Andrzejewska , Michalina Wilkowska, Barbara Peplińska, Maciej Kozak 2171-Pos Board B187 ABIOTIC FABRICATION OF SUGAR PHOSPHATES AND RIBONUCLEOSIDES IN WATER MICRODROPLETS.  Inho Nam , Jae Kyoo Lee, Hong Gil Nam, Richard N. Zare Protein-Nucleic Acid Interactions III (Boards B188–B216) 2172-Pos Board B188 SENSITIZED DSDNA-PEPTIDE COMPLEX AND ITS PHYSICOCHEMICAL PROPERTIES. Paweł Wityk , Janusz Rak 2173-Pos Board B189 A GENERAL SAXS-BASED SCREENING PROTOCOL VALIDATED IN RNA- PROTEIN INTERACTIONS. Po-chia Chen , Pawel Masiewicz, Vladimir Rybin, Dmitri Svergun, Janosch Hennig 2174-Pos Board B190 ALLOSTERIC CONTROL OF HUMAN CGAS DIMERIZATION UNDERPINS ITS CONTEXT-DEPENDENT RESPONSE TO CYTOPLASMIC DNA . Richard Hooy , Jungsan Sohn 2175-Pos Board B191 VIZUALIZING THE MECHANISM OF H-NS GENE REGULATION. Kathy R. Chaurasiya , Ramon van der Valk, Bram Henneman, Remus T. Dame 2176-Pos Board B192 G QUADRUPLEX AND STEM INTERACTIONS IN RGG BOX DOMAIN RECOGNITION. Kendy A. Pellegrene , Mihaela-Rita Mihailescu, Jeffrey D. Board B193 A COMPARISON OF BASIC SIDE CHAIN INTERNAL MOTIONS FOR THE FREE AND DNA-BOUND STATES OF THE ANTENNAPEDIA HOMEODOMAIN. Dan Nguyen , Zoe A. Hoffpauir, Junji Iwahara 2178-Pos Board B194 International Travel Awardee MECHANISTIC INSIGHT INTO THE ASSEMBLY OF THE HERA-NURA HELI- CASE-NUCLEASE DNA END RESECTION COMPLEX USING NATIVE MASS SPECTROMETRY. Zainab Ahdash , Andy M. Lau, Robert Thomas Byrne, Katja Lammens, Paula J. Booth, Eamonn Reading, Karl-Peter Hopfner, Argyris Politis 2179-Pos Board B195 ARE CAJAL BODIES DROPLET ORGANELLES? Edward M. Courchaine , Karla M. Neugebauer 2180-Pos Board B196 LIQUID-LIQUID PHASE TRANSITIONS AT THE ORIGINS OF LIFE? Helen G. Hansma 2181-Pos Board B197 PROTEIN-SENSING RIBOSWITCHES. Roee amit 2182-Pos Board B198 WIDESPREAD INCREASE IN TRANSCRIPTION FACTOR-DNA BINDING DUE TO MISMATCH DAMAGE. Ariel Afek , Raluca Gordan Evanseck 2177-Pos

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