Biophysical Society 62nd Annual Meeting | Program Guide

2718-Plat 9:30 am IN SITU REPLACEMENT OF CMYBP-C N’-TERMINAL DOMAINS USING THE NOVEL SPY-C METHOD.  Katia Touma, Sabine J. van Dijk, Joshua Strom, Samantha P. Harris 2719-Plat 9:45 am ENGINEERED HEART TISSUES EXPRESSING MUTANT DESMOPLAKIN EXHIBIT ALTERED TWITH KINETICS.  Ronald Ng , Xia Li, Heather Manring, Jinkyu Park, Jiesi Luo, Daniel Jacoby, Maegen A. Ackermann, Stuart 10:00 am CREATINE-KINASE SHUTTLE AND RAPID MITOCHONDRIAL MEMBRANE POTENTIAL CONDUCTIVITY ARE NEEDED SIMULTANEOUSLY TO MAINTAIN UNIFORMMETABOLITE DISTRIBUTIONS IN THE CARDIAC CELL CONTRAC- TION CYCLE.  Shouryadipta Ghosh , Kenneth Tran, Edmund Crampin, Eric Hanssen, Vijay Rajagopal Platform Membrane Dynamics and Fusion II 8:15 am–10:15 am, Esplanade, Room 154 Co-Chairs Ilya Levental, University of Texas Medical School at Houston David Weliky, Michigan State University 2721-Plat 8:15 am SPATIO-TEMPORAL DYNAMICS AND TURNOVER OF LIPOPOLYSACCHA- RIDE IN THE BACTERIAL OUTER MEMBRANE.  Sam Lenton , Rosalyn M. Leaman, Richard J. Spears, Martin A. Fascione, Dmitri O. Pushkin, Mark C. Coles, Christoph G. Baumann 2722-Plat 8:30 am Education Travel Awardee THE BIOPHYSICAL ASYMMETRY OF MAMMALIAN PLASMA MEMBRANES.  Joseph H. Lorent , Eric Malmberg, Ilya Levental 2723-Plat 8:45 am FORMATION AND STABILITY OF MEMBRANE NECKS FROMMOLECULAR SIMULATION.  Rikhia Ghosh , Andrea Grafmüller, Reinhard Lipowsky 2724-Plat 9:00 am DIFFUSION OF PROTEINS AND LIPIDS IN PROTEIN-RICH MEMBRANES.  Matti Javanainen, Hector Martinez-Seara, Ralf Metzler, Ilpo Vattulainen 2725-Plat 9:15 am GENERAL NON-AXISYMMETRIC SHAPES OF BIOLOGICAL MEMBRANES AND THEIR IMPORTANCE IN UNDERSTANDING ENDOCYTOSIS.  Kranthi K. Mandadapu , Yannick Omar, amaresh Sahu, Roger Sauer 2726-Plat 9:30 am CID Travel Awardee MOLECULAR MECHANISM OF MICRODOMAIN DEPENDENT PROTEIN TRAFFICKING.  Blanca B. Diaz-Rohrer , Kandice R. Levental, Ilya Levental 2727-Plat 9:45 am CAPACITIVE DETECTION OF LOW-ENTHALPY, HIGHER-ORDER PHASE TRANSITIONS IN SYNTHETIC AND NATURAL LIPID MEMBRANES.  Graham J. Taylor , Frederick A. Heberle, John Katsaras, C. Patrick Collier, Stephen A. Sarles 2728-Plat 10:00 am NMR CONTACTS BETWEEN THE HIV FUSION PEPTIDE AND LIPID SUPPORT A BETA-BOWL MEMBRANE TOPOLOGY OF THE PEPTIDE WITH THERMO- DYNAMIC PREFERENCE FOR PEPTIDE/CHOLESTEROL CONTACT.  David Weliky Campbell 2720-Plat

2707-Plat 8:45 am SUPER RESOLUTION IMAGING OF START TRANSCRIPTION FACTORS IN YEAST.  Labe Black , Jean-Bernard Fiche, Sylvain Tollis, Jing Cheng, Stephen Notley, Ben Crevier, Michael Tyers, Marcelo Nollmann, Catherine Royer 2708-Plat 9:00 am TWO-COLOR 3D STORM REVEALS CILIARY TRANSITION ZONE ARCHI- TECTURE AND ITS ROLE IN CILIARY SIGNALING.  Xiaoyu Shi , Galo Garcia, Jeremy F. Reiter, Bo Huang 2709-Plat 9:15 am VISUALIZING DYNAMIC MICROVILLAR SEARCH AND STABILIZATION DUR- ING LIGAND DETECTION BY T CELLS.  En Cai , Kyle Marchuk, Peter Beemi- ller, Casey Beppler, Matthew G. Rubashkin, Valerie M. Weaver, Audrey Gérard, Tsung-Li Liu, Bi-Chang Chen, Eric Betzig, Frederic Bartu- meus, Matthew F. Krummel 2710-Plat 9:30 am LIGHT-SHEET MICROSCOPY ALLOWS SIMULTANEOUS IMAGING OF SECOND MESSENGERS IN INTACT PANCREATIC ISLETS.  Zeno Lavagnino , Michael DiGruccio, David W. Piston 2711-Plat 9:45 am ROTOR-BASED ORGANELLE VISCOSITY IMAGING. Markéta Kubánková , Joseph E. Chambers, Stefan J. Marciniak, Marina K. Kuimova 2712-Plat 10:00 am A POLAR MATRIX MICRODOMAIN CONSTRAINS DIFFUSION AND REGU- LATES INTRACELLULAR SIGNALING.  Alex von Diezmann , Keren Lasker, Thomas H. Mann, Daniel G. Ahrens, Lucy Shapiro, W. E. Moerner Platform Cardiac Muscle Mechanics, Structure, and Regulation II 8:15 am–10:15 am, Esplanade, Room 153 Co-Chairs Jonathan Kirk, Loyola University Chicago Matthew Caporizzo, The University of Pennsylvania 2713-Plat 8:15 am LENGTH-DEPENDENT ACTIVATION IS REDUCED IN MYOCARDIUM FROM PATIENTS WITH NON-ISCHEMIC HEART FAILURE.  Bertrand C.W. Tanner , Peter O. Awinda, Cheavar A. Blair, Maya A. Guglin, Kenneth S. Campbell 2714-Plat 8:30 am CARDIAC MUSCLE REGULATORY UNITS ARE PREDICTED TO INTERACT STRONGER THAN NEIGHBORING CROSS-BRIDGES. Mari Kalda , Marko Vendelin 2715-Plat 8:45 am HUMAN EMBRYONIC STEM-CELL DERIVED CARDIOMYOCYTES: SINGLE- CELL MAPPING TO RELATE TWITCH KINETICS TO MYOSIN HEAVY CHAIN PROTEIN AND MRNA-EXPRESSION.  Natalie Weber, Kathrin Kowalski, Tim Holler, Ante Radocaj, Kristin Schwanke, Alexander Lingk, Uwe Krumm, Meike Wendland, Urs Zywietz, Boris Chichkov, Ulrich Martin, Robert Zweigerdt, Bernhard Brenner, Theresia Kraft 2716-Plat 9:00 am LIVE CELL PALM TECHNIQUES FOR SUPER RESOLUTION IMAGING OF MURINE CARDIAC MYOCYTES.  Yufeng Hou , Ornella Manfra, Jia Li, Xin Shen, William E. Louch 2717-Plat 9:15 am UNDERSTANDING CARDIAC TUBE FORMATION IN DEVELOPING DRO- SOPHILA EMBRYOS USING LIGHT SHEET MICROSCOPY AND CARDIAC DRUG SCREENING.  Christopher MJ McFaul , Rodrigo Fernandez- Gonzalez, Christopher M. Yip

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