Biophysical Society 62nd Annual Meeting | Program Guide

2833-Pos Board B41 DISSECTING THE DIVERGENT FUNCTIONS AND DYNAMICS OF ZAP-70 AND SYK. Helen T. Hobbs , Neel Shah, Susan Marqusee, John Kuriyan 2834-Pos Board B42 USING PH CHANGES TO OBTAIN TIME-RESOLVED CRYSTALLOGRAPHIC STRUCTURES OF HMG-COA REDUCTASE. Vatsal Purohit , Tony Rosales, Chandra Duncan, Calvin Steussy, Cynthia Stauffacher 2835-Pos Board B43 ROLE OF EXPORT CHAPERONES IN REGULATION OF FLAGELLUM ASSEM- BLY. Nandish K. Khanra , Paolo Rossi, Charalampos Kalodimos 2836-Pos Board B44 EFFECTS OF NATURAL POLYMORPHISMS OF NON-B HIV-1 PROTEASE ON PROTEIN CONFORMATIONS. Trang Tran , Zhanglong Liu, Gail Fanucci 2837-Pos Board B45 STRUCTURAL AND MECHANISTIC INSIGHT INTO HOW PATHOGENIC BAC- TERIA ASSEMBLE ADHESIVE SURFACE PILI VIA ISOPEPTIDE BONDS. Scott A. McConnell 2838-Pos Board B46 SOLUTION NMR STUDY OF A CYTOCHROME C MUTANT(A44C) WITH EN- HANCED APOPTOTIC ACTIVITY. Manoj Saxena , Johnathan Dallman, Ana B. Castaner, Marvin J. Bayro, Kai Griebenow Protein Structure, Prediction, and Design II (Boards B47–B64) 2839-Pos Board B47 PREDMP: A WEB RESOURCE FOR COMPUTATIONALLY PREDICTED MEM- BRANE PROTEINS VIA DEEP LEARNING. Sheng Wang , Shiyang Fei, Wang Zongan, Yu Li, Feng Zhao, Xin Gao 2840-Pos Board B48 HOMOLOGY MODELLING OF SODIUM IODIDE SYMPORTER. Hristina R. Zhekova , Igor Zdravkovic, Sergei Yu. Noskov, Toshie Sakuma, Susanna C. Concilio, Ryan Johnson, Stephen J. Russell, Kah-Whye Peng 2841-Pos Board B49 DE NOVO PROTEIN STRUCTURE PREDICTION BY COMBINING REPLICA EX- CHANGE SIMULATIONS WITH COEVOLUTIONARY DATA. Arthur Voronin , Alexander Schug 2842-Pos Board B50 MELD FOLDS NONTHREADABLE PROTEINS.  James Robertson , Alberto Perez, Ken Dill 2843-Pos Board B51 EFFICIENT SAMPLING FOR THE PREDICTION OF LONG AND MULTIDO- MAIN PROTEIN STRUCTURES. Clare E. West , Saulo H P de Oliveira, Elea- nor C. Law, Sebastian Kelm, Jiye Shi, Charlotte M. Deane 2844-Pos Board B52 NOVEL COARSE-GRAINING APPROACHES FOR LARGE SCALE PROTEIN MODELING. Aleksandra E. Dawid, Andrzej Koliński, Dominik Gront 2845-Pos Board B53 COMPENSATORY MUTATIONS IN PROTEIN SEQUENCES FROM BIG-DA- TA. Kejue Jia , Robert L. Jernigan 2846-Pos Board B54 PROTEIN STRUCTURE REFINEMENT VIA MOLECULAR DYNAMICS SIMULA- TIONS. Michael Feig , Lim Heo 2847-Pos Board B55 FROM SINGLE STRUCTURES TO ENSEMBLES: APPLICATION OF THE GAL- AXY PROGRAM SUITE TO UBIQUITIN, CYCLOPHILIN A AND PTP1B. Gyu Rie Lee, Chaok Seok, Matthias Buck

2818-Pos Board B26 SINGLE-MOLECULE ATOMIC FORCE MICROSCOPY OF BLOOD COAGULA- TION FACTOR XIII AND ITS SUBUNITS. Anna D. Protopopova, Andrea Ramirez, Rustem I. Litvinov , John W. Weisel 2819-Pos Board B27 CRYO-EM STUDIES OF ATPASES AND SUBSTRATE ENGAGEMENT. Colby Sandate 2820-Pos Board B28 SHEDDING LIGHT ON NIGHT OWL BEHAVIOR: HOW THE DISORDERED C-TERMINAL TAIL OF CRY1 MODULATES CIRCADIAN TIMEKEEPING. Gian Carlo Parico , Ivette Perez, Carrie Partch 2821-Pos Board B29 ROLE OF THE DILEUCINE MOTIF IN NEF-INDUCED TRIMERIZATION OF THE ARF1:AP-1 CLATHRIN ADAPTOR COMPLEX. Cosmo Z. Buffalo , Kyle L. Mor- ris, Xuefeng Ren, James H. Hurley 2822-Pos Board B30 BIOCHEMICAL CHARACTERISATION OF LECTIN FROM INDIAN HYACINTH PLANT BULBS WITH POTENTIAL INHIBITORY ACTION AGAINST HUMAN CANCER CELLS. Sanjit Kumar , Sanjay Naik, Ravindra Singh Rawat 2823-Pos Board B31 STRUCTURAL STUDIES OF MAGNESIUM TRANSPORTER CNNM. Yu Chen , Meng Yang, Rayan Fakih, Guennadi Kozlov, Kalle Gehring 2824-Pos Board B32 INSIGHT INTO LIGAND BINDING AND CONFORMATIONAL DYNAMICS OF KYNURENINE 3-MONOOXYGENASE. Rajni Verma , Katie Mitchell-Koch 2825-Pos Board B33 INVESTIGATING THE ROLE OF THROMBOMODULIN IN THE ACTIVATION OF COMPLEMENT.  Julia R. Koeppe , Gary Ellis, Nicholas Joannides, Van- essa Wiltsie 2826-Pos Board B34 HOST-PATHOGEN INTERACTIONS VIA UBIQUITINATION PATHWAYS. Kathy Wong , Guennadi Kozlov, John D. Perpich, Miroslaw Cygler, Yousef Abu Kwaik, Kalle Gehring 2827-Pos Board B35 INTERACTIONS OF FRATAXIN WITH ISCU AND FERREDOXIN ON THE CYS- TEINE DESULFURASE COMPLEX LEADING TO FE-S CLUSTER ASSEMBLY. Kai Cai 2828-Pos Board B36 STRUCTURE AND MEMBRANE BINDING OF R9AP, A MEMBRANE- ANCHOR PROTEIN. Sarah Bernier , Marc-Antoine Millette, Line Cantin, Christian Salesse 2829-Pos Board B37 Education Travel Awardee STRUCTURE-FUNCTION STUDIES OF THE HYPOXIA-INDUCIBLE PROYLY HY- DROXYLASES. Pamela N. Gallo , Kayla Schardien, Taylor Keagy, Nathaniel V. Nucci 2830-Pos Board B38 UNDERSTANDING AAV PACKAGING. Vishaka Santosh 2831-Pos Board B39 SIMULTANEOUS REAL-TIME OBSERVATION OF DNA UNWINDING AND NUCLEASE DOMAIN ACTIVATION IN CAS9-RNA-DNA COMPLEX VIA THREE-COLOR SINGLE MOLECULE FRET. Yanbo Wang , Digvijay Singh, John Mallon, Boyang Hua, Scott Bailey, Taekjip Ha 2832-Pos Board B40 STRUCTURAL AND KINETIC CHARACTERIZATION OF HIGH-AFFINITY LEAD(II)-SYNAPTOTAGMIN I INTERACTIONS. Sachin Katti , Bin Her, Atul Srivastava, Alexander B. Taylor, P. John Hart, Steve Lockless, Tatyana Igumenova

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