Biophysical Society 62nd Annual Meeting | Program Guide

70-Symp 8:45 am PROTEIN-MEDIATED LOOPS IN SUPERCOILED DNA GENERATE LARGE, DYNAMIC TOPOLOGICAL DOMAINS.  Laura Finzi 71-Symp 9:15 am ORGANISATION AND FUNCTION OF DNA SUPERCOILING IN THE HUMAN GENOME.  Nick Gilbert 72-Symp 9:45 am THE ROLE OF DNA TOPOLOGY AND CONFORMATION IN GENE REGULATION, IN VIVO.  David Levens , Fedor Kouzine, Laura F. Baranello Platform Optical Microscopy and Superresolution Imaging: Methods I 8:15 am–10:15 am, South, Level Two, Room 207/208 Co-Chairs Samuel Hess, University of Maine Xiyu Yi, University of California, Los Angeles 73-Plat 8:15 am THE ROLE OF PROBE PHOTOPHYSICS IN LOCALIZATION-BASED SUPER- RESOLUTION MICROSCOPY.  Francesca Pennacchietti, Travis J. Gould, Samuel T. Hess 74-Plat 8:30 am PUSHING THE BOUNDARY OF STORM RESOLUTION: SEEING THE ACTIN LATTICE IN MUSCLE.  Sheema Rahmanseresht , Kyounghwan Lee, Jeffrey Robbins, David M. Warshaw, Roger Craig, Michael J. Previs 75-Plat 8:45 am FAST SUPER RESOLVED IMAGING OF LIVE CELLS USING SUPERRESOLU- TION OPTICAL FLUCTUATION IMAGING 2.0 (SOFI-2.0).  Xiyu Yi , Sungho Son, Shimon Weiss 76-Plat 9:00 am 3D SINGLE-MOLECULE SUPERRESOLUTION MICROSCOPY IN MAMMA- LIAN CELLS USING A TILTED LIGHT SHEET.  Anna-Karin Gustavsson , Petar N. Petrov, Maurice Y. Lee, Yoav Shechtman, W. E. Moerner 77-Plat 9:15 am IMAGING COMPLEX PROTEIN MACHINES BY HIGH-THROUGHPUT LOCAL- IZATION MICROSCOPY.  Joran Deschamps , Markus Mund, Jonas Ries 78-Plat 9:30 am OPTIMIZATION OF HIGHLY INCLINED OPTICAL SHEET ILLUMINATION FOR SUPERRESOLUTION MICROSCOPY.  Tiziano Vignolini, Lucia Gardini, Valentina Curcio, Marco Capitanio , Francesco Saverio Pavone 79-Plat 9:45 am GRAPHENE BIOINTERFACES FOR OPTICAL STIMULATION OF GENETI- CALLY INTACT CELLS.  Alex Savtchenko , Volodymyr Cherkas, Alexander Kleschevnikov, Gary Braun, Aliaksandr Zaretski, Darren L. Lipomi, Ke Wei, Elena Molokanova 80-Plat 10:00 am A NEWMETHOD (SIGMA-SHREC) FOR TWO-COLOR FLUORESCENT DISTANCE MEASUREMENTS WITH NANOMETER ACCURACY.  Stefan Niekamp , Jongmin Sung, Walter Huynh, Ronald D. Vale, Nico Stuurman

Sunday, February 18

S U N D A Y

Editorial Board Boot Camp 7:00 am–9:00 am, South, Level Three, Room 313 Postdoctoral Breakfast 7:30 am–8:30 am, South, Level Three, Room 307/308 Support contributed by the Burroughs Wellcome Fund. This breakfast presents an opportunity for postdoctoral Annual Meeting attendees to meet and discuss the issues they face in their current career stage. Limited to the first 100 attendees. Panelists Shawnna Buttery, Editor, Cell Reports Darren Hwee, Group Leader, Cytokinetics Mana Candida Vila Registration/Exhibitor Registration 7:30 am–5:00 pm, South Lobby Poster Viewing 8:00 am–10:00 pm, Exhibit Hall ABC Symposium Biophysical Mechanisms of Molecular Evolution 8:15 am–10:15 am, North, Lower Lobby, Room 24 Co-Chairs Michael Harms, University of Oregon Claus Wilke, University of Texas, Austin 65-Symp 8:15 am STRUCTURAL AND FUNCTIONAL CONSTRAINTS ON PROTEIN EVOLUTION. Claus O. Wilke 66-Symp 8:45 am MOLECULAR ENSEMBLES SHAPE EVOLUTIONARY TRAJECTORIES.  Michael J. Harms , Zachary R. Sailer, Lucas C. Wheeler 67-Symp 9:15 am CELLULAR CONSEQUENCES OF SYSTEMATIC PERTURBATIONS OF A HIGHLY CONSERVED BIOLOGICAL SWITCH.  Tanja Kortemme 68-Symp 9:45 am AN ALTERNATIVE STRATEGY TO GENERATE BINDING PROTEINS.  Andreas Plueckthun Symposium DNA Supercoiling 8:15 am–10:15 am, North, Lower Lobby, Room 25 Co-Chairs Laura Finzi, Emory University Sarah Harris, University of Leeds, United Kingdom 69-Symp 8:15 am SEEING SUPERCOILED DNA WITH ATOMISTIC SIMULATION: A NEW TWIST ON A FAMILIAR STRUCTURE.  Sarah A. Harris , Agnes Noy, Thana Sutthibutpong

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