Biophysical Society 62nd Annual Meeting | Program Guide

3180-Pos Board B388 VOLATILE ANAESTHETICS INHIBIT THERMOSENSITIVE TRPM3 ION CHAN- NELS. Balázs Kelemen , Flóra Kulin, Erika Lisztes, János Posta, Thomas Voets, Tamás Bíró, Balázs István Tóth 3181-Pos Board B389 G-PROTEIN BETA-GAMMA SUBUNITS INHIBIT THE HEAT-SENSITIVE TRPM3 ION CHANNELS. Tibor Rohacs , Yevgen Yudin, Doreen Badheka, Istvan Borbiro, Aysenur Yazici, Siyuan Zhao, Cassandra Hartle, Tooraj Board B390 TRPM7 CURRENT INACTIVATION: EVIDENCE FOR INSIDE-OUT SIGNAL- ING. Tetyana Zhelay, J. Ashot Kozak 3183-Pos Board B391 PIP 2 DEPLETION CONTRIBUTES TO INHIBITION OF TRPM8 ACTIVITY BY G Q PROTEIN COUPLED RECEPTORS. Luyu Liu , Yevgen Yudin, Tibor Rohacs 3184-Pos Board B392 TRPM8 REGULATES SEXUAL DESIRE AND SATIETY. Lusine Demirkhanyan , Vivek Krishnan, Swapna Asuthkar, Brenda Alexander, Zahir Hussain, Pad- mamalini Baskaran, Yelena Nersesyan, Alejandro Cohen, Evgeny Pavlov, Baskaran Thyagarajan, Eleonora Zakharian 3185-Pos Board B393 MOLECULAR ELEMENTS FOR TEMPERATURE DETECTION IN TRPM8 CHANNEL. Karen Castillo , Natalia Raddatz, Melissa Alegría-Arcos, Ger- man Mi o-Galaz, Ignacio Diaz-Franulic, Fernando Gonzalez-Nilo, Ramon Latorre 3186-Pos Board B394 IDENTIFICATION OF CLUSTERED PHOSPHORYLATION SITES IN PKD2L1: HOW PKD2L1 CHANNEL ACTIVATION IS REGULATED BY CYCLIC amP SIG- NALING PATHWAY. Eunice Y. Park , Misun Kwak, Kotdaji Ha, Insuk So 3187-Pos Board B395 POLYCYSTIN-1/POLYCYSTIN-2 MEDIATED CALCIUM ENTRY INTO CILIA DURING SONIC HEDGEHOG SIGNALING. Bryn S. Moore , Ann N. Stepanch- ick, Jonathan Z. Luo, Tooraj Mirshahi 3188-Pos Board B396 International Travel Awardee REGULATION OF CILIARY LENGTH IN LLC-PK1 RENAL EPITHELIAL CELLS. Paula L. Perez , Noelia Scarinci, Maria del Rocio Cantero, Horacio F. Board B397 FUNCTIONAL CHARACTERIZATION OF A CALCIUM-SENSING RECEPTOR- POLYCYSTIN-2 CHANNEL COMPLEX IN THE PLASMA MEMBRANE OF LLC-PK1 CELLS. Noelia Scarinci , Paula L. Perez, Maria del Rocio Cantero, Horacio F. Cantiello 3190-Pos Board B398 ACTIVATION MECHANISMS UNDERLYING INFLUX-OPERATED CALCIUM ENTRY OF TRPP CHANNELS. Liu Yuxia Skeletal Muscle Mechanics, Structure, and Regulation II (Boards B399–B411) 3191-Pos Board B399 AN IN-SITU STUDY OF THE MODULATION OF THE MECHANO-KINETIC PARAMETERS OF THE SLOW ISOFORM OF MUSCLE MYOSIN II BY THE HEART DRUG OMECAMTIV MECARBIL. Marco Caremani, Cristina Gallart, Valentina Percario, Gabriella Piazzesi, Vincenzo Lombardi, Marco Linari 3192-Pos Board B400 MYOSIN EFFECTS ON THIN FILAMENT ACTIVATION IN SLOW-TWITCH HUMAN SOLEUS MUSCLE FIBERS. Alfredo J. Lopez-Davila , Robert Stehle, Stefan Zittrich, Birgit Piep, Faramarz Matinmehr, Andras Malnasi, Anna Rauscher, Joseph Chalovich, Theresia Kraft, Bernhard Brenner Mirshahi 3182-Pos Cantiello 3189-Pos

3167-Pos Board B375 CARBOXYL TERMINUS AS A KEY REGULATOR OF GATING AND SIGNALING OF L-TYPE CALCIUM CHANNELS. Yaxiong Yang, Yuanyuan He, Xiaodong Liu 3168-Pos Board B376 PROBING THE PATHOGENIC MECHANISMS UNDERLYING CA V 1.2 CHAN- NELOPATHIES. Moradeke A. Bamgboye , Maria K. Traficante, David T. Yue, Board B377 DIRECT INHIBITION OF CAV2.3 BY GEM DOES NOT REQUIERE A DIRECT ALPHA1E/BETA INTERACTION. Gustavo F. Contreras , Nieves Navarro, Guido Mellado, Daniela De Giorgis, Carlos Gonzalez, Alan Neely 3170-Pos Board B378 A SKELETAL MUSCLE L-TYPE CALCIUM CHANNEL WITH A MUTATION WITHIN THE SELECTIVITY FILTER CONDUCTS POTASSIUM. Roger A. Bannister , Donald Beqollari TRP Channels II (Boards B379–B398) 3171-Pos Board B379 DROSOPHILA -INSPIRED MOLECULAR THERMOSENSORS. Marzie Amirshenava , Benjamin Zars, Benton Berigan, Paige Martinez, Troy Zars, Lorin S. Milescu, Mirela Milescu 3172-Pos Board B380 IP6 DOES NOT INDUCE BINDING BETWEEN COILED-COIL HELICES OR BETWEEN THE N-TERM ARDS AND COILED-COIL. Gilbert Q. Martinez , Sharona E. Gordon 3173-Pos Board B381 DISTINCTIVE DRUG BINDING SITES AND GATING MECHANISMS OF THE NOCICEPTIVE ION CHANNEL TRPA1.  Jun Chen , Tania Chernov-Rogan 3174-Pos Board B382 TRPC3 UNDERLIES GABA B RECEPTOR-MEDIATED AUGMENTATION OF TYPE-1 METABOTROPIC GLUTAMATE RECEPTOR-COUPLED SLOW EX- CITATORY POSTSYNAPTIC POTENTIAL IN CEREBELLAR PURKINJE NEU- RONS.  JinBin Tian , Michael X. Zhu 3175-Pos Board B383 PHOTOSWITCHABLE DIACYLGLYCEROLS IDENTIFY A NOVEL LIPID-GATING MECHANISM IN TRPC3 CHANNELS. Oleksandra Tiapko , Michaela Lichtenegger, Gema Guedes de la Cruz, Toma N. Glasnov, Barbora Svobo- dova, Wolfgang Schreibmayer, Dieter Platzer, Sarah Krenn, Niroj Shrestha, Rainer Schindl, Thomas Stockner, Christoph Romanin, Klaus Groschner 3176-Pos Board B384 CA 2+ -DEPENDENT INACTIVATION MEDIATED BY CALMODULIN IN TRPC6 CHANNEL UNDERLIES FSGS CHANNELOPATHY. Masatoshi Uno, Onur K. Polat , Tran Nam Ha, Shota Yamaji, Yasuo Mori, Hidehito Tochio, Masayuki X. Mori 3177-Pos Board B385 Education Travel Awardee ISCHEMIC NEURONAL CELL DEATH MEDIATED BY TRPC CHANNELS.  Jaepyo Jeon , Sun Guanghua, Jinbin Tian, Sung-Ming Ting, Jaroslaw Aronowski, Michael X. Zhu 3178-Pos Board B386 FUNCTIONAL CHARATERIZATION OF ZEBRAFISH TRANSIENT RECEPTOR POTENTIAL MELASTATIN 2. Ha Nam Tran , Jure Hederih, Tomohiro Nu- mata, Masayuki X. Mori, Shingo Maegawa, Hiroshi Hosokawa, Yasuo Mori 3179-Pos Board B387 BIOCHEMICAL CHARACTERIZATION OF THE INTERACTION OF TRPM3 WITH G ΒΓ PROTEINS. Fabian Gruss , Marc Behrendt, Mieke Nys, Johannes Oberwinkler, Chris Ulens Ivy E. Dick 3169-Pos

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