Biophysical Society 62nd Annual Meeting | Program Guide

DNA Structure and Dynamics I (Boards B210–B229.1)

426-Pos Board B196 CIRCULOMICS: THE STRUCTURAL GENOMICS OF ENDOGENOUS AND

EXOGENOUS EXTRACHROMOSOMAL CIRCULAR DNAS.  Stephen D. Levene , Massa J. Shoura, Andrew Z. Fire 427-Pos Board B197

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440-Pos Board B210 FOLDING/UNFOLDING THERMODYNAMICS OF THREE-WAY AND FOUR- WAY JUNCTIONS. Luis A. Marky , Carolyn E. Carr 441-Pos Board B211 UNEXPECTED DISCONTINUOUS SUPERCOILING OF TORSIONALLY BUCKLED DNA: EVIDENCE FOR A SOLENOID? Andrew Dittmore , Keir C. Board B212 DIRECT MEASUREMENT OF TORQUE INDUCED TELOMERE STRAND INVASION USING MAGNETIC TWEEZERS. Xi Long, Terren Chang , Shankar Shastry, Joeseph W. Parks, Michael D. Stone 443-Pos Board B213 SINGLE MOLECULE MEASUREMENT OF DNA FOLDING BY PROT- AMINES. Luka Matej Devenica , Bishop Grimm, Ashley R. Carter 444-Pos Board B214 ISOTHERMAL CALORIMETRY INVESTIGATION OF DNA COMPACTION UNDER OSMOTIC STRESS. Kurt Andresen , amlan Chowdhury 445-Pos Board B215 1-PROPANOL CAUSES REENTRANT TRANSITION ON DNA WHEREAS 2-PROPANOL DOES NOT: EXPERIMENTAL VERIFICATION THROUGH SINGLE MOLECULAR OBSERVATION. Yue Ma , Yuko Yoshikawa, Koichiro Sadakane, Kenichi Yoshikawa 446-Pos Board B216 THE BINDING KINETICS AND MECHANICAL PROPERTIES OF DNA-YOYO-1 COMPLEXES. Ali A. Almaqwashi , Mark C. Williams 447-Pos Board B217 STRONG ACCUMULATION OF DNA AT A HEATED AIR-WATER INTERFACE. Jonathan Liu , Matthias Morasch, Dieter Braun 448-Pos Board B218 CID Travel Awardee STRUCTURE-HYDRATION RELATIONSHIPS IN DNA MINOR GROOVE BIND- ING. Noa Erlitzki , Abdelbasset A. Farahat, Arvind Kumar, David W. Boykin, Gregory M.K. Poon 449-Pos Board B219 THE EFFECT OF CATION SIZE ON DNA THERMAL STABILITY. Earle Stellwa- gen, Nancy C. Stellwagen 450-Pos Board B220 ELASTIC PROPERTIES OF DNA AS THE ENTROPIC DRIVING FORCE FOR DEHYBRIDIZATION TRANSITIONS. Sebastian Sensale , Hsueh-Chia Chang, Zhangli Peng 451-Pos Board B221 EXPERIMENTALLY MOTIVATED SEQUENCE-DEPENDENT MODELS OF MELTING AND OVERSTRETCHING FOR DIAMINOPURINE-SUBSTITUTED DNA. Daniel T. Kovari , Matteo Cristofalo, Roberta Corti, Domenico Salerno, Valeria Cassina, Yoojin Lee, Geethika Malla, Laura Finzi, Fran- cesco Mantegazza, David Dunlap 452-Pos Board B222 PROBING CHANGES IN IONIC ATMOSPHERE AND HYDRATION ACCOMPA- NYING I-MOTIF FORMATION. Lutan Liu 453-Pos Board B223 GLOBAL STRUCTURAL DEFORMATIONS OBSERVED THROUGH OPTIMIZA- TION CALCULATIONS OF SMOOTHLY BENT AND MINI-KINKED CLOSED DNA. Robert T. Young , Wilma Olson Neuman 442-Pos

CIRCULOMICS: ULTRASENSITIVE CHARACTERIZATION OF EXTRACHROMO- SOMAL CIRCULAR DNA (ECCDNA) DISTRIBUTIONS AND FUNCTIONS IN EUKARYOTES. Massa Shoura , Stephen Levene, Andrew Fire 428-Pos Board B198 MASSIVELY PARALLEL MEASUREMENT OF DNA MISMATCH REPAIR EFFICIENCY IN VIVO. Tunc Kayikcioglu , Chang-Ting Lin, Taekjip Ha 429-Pos Board B199 PHYSICAL BIOLOGY OF MEIOTIC CHROMOSOME PAIRING IN THE NEMA- TODE LINEAGE. Baris Avsaroglu , Kayla Baskevitch, Abby Dernburg 430-Pos Board B200 A GENOME EDITED PIG WITH THE HYPERTROPHIC CARDIOMYOPATHY- MUTATION R723G IN THE MYH7- GENE.  Judith Montag , Björn Petersen, Anna Katharina Flögel, Edgar Becker, Andrea Lucas-Hahn, Gregory J. Cost, Christian Mühlfeld, Theresia Kraft, Heiner Niemann, Bernhard Brenner 431-Pos Board B201 VERTEBRATE ENDONUCLEASE G PREFERENTIALLY CLEAVES HOLLIDAY JUNCTIONS AND SPECIFICALLY RECOGNIZES 5-HYDROXYMETHYLCYTO- SINE. Crystal M. Vander Zanden , Adam B. Robertson, Shing P. Ho 432-Pos Board B202 COMPUTATIONAL ANALYSIS OF DNA HOMOLOGOUS RECOMBINATION PATHWAY IN A FOLDBACK INTERCOIL STRUCTURE. Byung Ho Lee , Soojin Jo, Byung-Dong Kim, Sung Ha Park, Moon Ki Kim 433-Pos Board B203 MOLECULAR DYNAMICS SIMULATION STUDY OF DNA MISMATCH RECOG- NITION BY COMPLEMENTARY STRAND INTERACTIONS IN THYMINE DNA GLYCOSYLASE. Ozge Yoluk , Alexander C. Drohat, Alexander D. MacKerell Jr. 434-Pos Board B204 HOMOLOGY MODELING AND STRUCTURAL ANALYSIS OF S. CEREVISIAE MSH4 AND MSH5 PROVIDE INSIGHT INTO DNA BINDING AND SPECIFIC- ITY. Sudipta Lahiri , Ishita Mukerji 435-Pos Board B205 VISUALIZING SPONTANEOUS DNA DYNAMICS AND ITS ROLE IN MIS- MATCH RECOGNITION BY DAMAGE RECOGNITION PROTEIN RAD4. Sagnik Chakraborty, Debamita Paul, Saroj Baral , Hong Mu, Peter J. Steinbach, Suse Broyde, Jung-Hyun Min, Anjum Ansari 436-Pos Board B206 SINGLE MOLECULE EXPERIMENTS REVEAL MOLECULAR LEVEL DETAILS OF MUTS-MUTL INTERACTIONS IN DNA MISMATCH ACTIVATED SLIDING CLAMP. Pengyu Hao , Sharonda LeBlanc, Dorothy Erie, Keith Weninger 437-Pos Board B207 HIGH-SPEED MAGNETIC TWEEZERS STUDIES OF THE E. COLI REPLI- SOME. Samuel M. Leachman , Nynke H. Dekker 438-Pos Board B208 ATP-DEPENDENT TOPOLOGY DISCRIMINATION BY TYPE IIA TOPOISOMER- ASES: IMPLICATIONS FOR BELOW EQUILIBRIUM TOPOLOGY SIMPLIFICA- TION. Yeonee Seol , Tamara Litwin, Lauren Kim, Laudan Nikoobakht, Neil Osheroff, Keir C. Neuman 439-Pos Board B209 SKEWING THE PLAYING FIELD: A SINGLE-MOLECULE STUDY ON HOW RSS SEQUENCE INFLUENCES GENE SEGMENT SELECTION. Soichi Hirokawa , Nathan M. Belliveau, Geoffrey A. Lovely, Michael Anaya, David G. Schatz, David Baltimore, Rob Phillips

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