Biophysical Society 62nd Annual Meeting | Program Guide

801-Pos Board B571 TRAJECTORY-BASED SIMULATIONS OF ELECTRON PARAMAGNETIC RESO- NANCE SPECTRA. Peter Martin , Stefan Stoll, David Thomas 802-Pos Board B572 PROTEIN-PROTEIN INTERACTIONS OF CO-RECONSTITUTED SERCA, PLB AND DWORF INVESTIGATED BY ELECTRON PARAMAGNETIC RESO- NANCE. Mark D. Rustad , Peter D. Martin, Daniel R. Stroik, Christine B. Karim, David D. Thomas 803-Pos Board B573 EXPLORATION OF EUKARYOTIC CELLS AND ORGANELLE NMR SIGNA- TURES. Sabrina H. Werby , Lynette Cegelski 804-Pos Board B574 CHARACTERIZATION OF LIGAND- AND ION-DEPENDENT DYNAMICS OF F. NUCLEATUM GLYCINE RIBOSWITCH APTAMER II VIA SITE-DIRECTED SPIN LABELING EPR. Michelle Ehrenberger Electron Microscopy (Boards B575–B598) 805-Pos Board B575 EFFECTS OF CRYO-EM FREEZING ON THE STRUCTURAL ENSEMBLE.  Lars V. Bock , Helmut Grubmüller 806-Pos Board B576 LASER-BASED ZERNIKE PLATE FOR PHASE CONTRAST TRANSMISSION ELECTRON MICROSCOPY. Osip Schwartz , Jeremy J. Axelrod, Robert M. Glaeser, Holger Müller 807-Pos Board B577 DUAL-ENERGY SERIAL BLOCK FACE SEM IMAGING OF BIOLOGICAL STRUC- TURES AT NEAR ISOTROPIC SPATIAL RESOLUTION. Qianping He , David C. Joy, Guofeng Zhang, Richard D. Leapman 808-Pos Board B578 HUMAN AND BACTERIAL CTP SYNTHASE FILAMENT STRUCTURE AND FUNCTION DIVERGE. Eric M. Lynch , Derrick R. Hicks, Matthew Shepherd, James A. Endrizzi, Allison Maker, Jesse M. Hansen, Rachael M. Barry, Zemer Gitai, Enoch P. Baldwin, Justin M. Kollman 809-Pos Board B579 STRUCTURAL STUDIES OF ALPHA-SYNUCLEIN amYLOID FILAMENTS.  Guilherme A. P. de Oliveira , Weili Zheng, Edward H. Egelman 810-Pos Board B580 FULLY AUTOMATED CORRELATION-BASED REFINEMENT OF ATOMIC MODELS INTO HIGH RESOLUTION CRYO-EM DENSITY MAPS.  Andrea C. Vaiana , Maxim Igaev, Carsten Kutzner, Helmut Grubmueller 811-Pos Board B581 TITLE–‘FIXING’ THE GATEWAY BETWEEN ELECTRON MICROSCOPY AND BSL3 VIRUSES. Amar D. Parvate , Evan Willaims, Colleen B. Jonsson, Jason K. Lanman 812-Pos Board B582 PH-GATING OF GAP JUNCTION CHANNELS: VISUALIZATION OF A “BALL- AND-CHAIN” BY CRYOEM. Ali K. Khan , Maciej J. Jagielnicki, Michael D. Purdy, Mark Yeager 813-Pos Board B583 RELIABILITY OF ELECTRON MICROSCOPY ATOMIC MODEL REFINE- MENT. Lyman Monroe , Genki Terashi, Daisuke Kihara 814-Pos Board B584 CRYO-ELECTRON MICROSCOPY OF A POLYHEDRAL VIRUS INFECTING HY- PERTHERMOPHILIC ARCHAEA. Fengbin Wang , Ying Liu, Thomas Edwards, Ulrich Baxa, Mart Krupovic, David Prangishvili, Edward H. Egelman

815-Pos Board B585 STRUCTURAL INSIGHTS INTO THE REGULATION MECHANISM OF HSP90 BY CO-CHAPERONE AHA1. Yanxin Liu , David A. Agard 816-Pos Board B586 RAPID SCREENING OF FABS FROM PHAGE DISPLAY LIBRARIES FOR STRUC- TURAL STUDIES. Evan Green , Natalia Sevillano, Nancy Li, Yifan Cheng, Charles Craik 817-Pos Board B587 A NOVEL FILAMENTOUS VIRUS INFECTS HYPERTHERMOPHILIC ACIDO- PHILES THAT LIVE IN NEARLY BOILING ACID. Tomasz Osinski , Fengbin Wang, Ying Liu, Mart Krupovic, David Prangishvili, Edward H. Egelman 818-Pos Board B588 ULTRASTRUCTURAL STUDY OF KERATINOCYTES AND MELANOCYTES IN SEBORRHEIC KERATOSIS. Seulgi Noh, Hyosun Choi, Il Whan Kim, Ji Young Mun 819-Pos Board B589 STREPTAVIDIN AFFINITY GRIDS FOR CRYO-EM. Robert M. Glaeser , Bong- Gyoon Han, Zoe Watson, Fred Ward, Jamie H. D. Cate 820-Pos Board B590 NOVEL METHODS FOR BIODISTRIBUTION ANALYSIS OF MAGNETIC NANOPARTICLES IN VIVO. Alicia Cascella , Ali Hadjikhani, Joseph Favata, Sina Shahbazmohamadi 821-Pos Board B591 HIGH RESOLUTION CRYO-EM STRUCTURE OF A HIV NEF-INHIBITED AP-1 CLATHRIN ADAPTOR COMPLEX. Kyle L. Morris , Cosmo Buffalo, Xuefeng Ren, James H. Hurley 822-Pos Board B592 STANDARDIZING THE FOCUSED ION BEAM-SEMWORKFLOW AS A TOOL FOR VERSATILE IMAGING OF CELLULAR STRUCTURES. Ashleigh M. Raczkowski , Edward T. Eng, William J. Rice, Sargis Dallakyan, Carl Negro, Laura Y. Kim, Kelsey D. Jordan, Bridget Carragher, Clinton S. Potter 823-Pos Board B593 STRUCTURE DETERMINATION OF amYLOID-Β FIBRILS BY CRYO-EM.  Carla T. Schenk 824-Pos Board B594 ACCOUNTING FOR MICROTUBULE DISTORTIONS IN CRYO-EM STRUC- TURES USING PATCH REFINEMENTS. Garrett Debs , Xueqi Liu, Hyo Keun Cha, Charles Sindelar 825-Pos Board B595 PUSHING SIZE AND RESOLUTION LIMITS OF SINGLE PARTICLE CRYO-EM AT 200 KEV. Mengyu Wu , Mark A. Herzik, Jr., Gabriel C. Lander 826-Pos Board B596 CRYO-EM STUDIES ON THE MECHANISM AND INHIBITION OF TARGET DNA BINDING IN THE TYPE I-F CSY SURVEILLANCE COMPLEX.  Edward T. Eng , Hui Yang, Ashleigh M. Raczkowski, Dinshaw Patel, Clint S. Potter, Bridget Carragher 827-Pos Board B597 ELECTRON TOMOGRAPHY TO VISUALIZE INDIVIDUAL IGM AND IGG MOLECULE USING CRYO-EM. Takeshi Mise , Ayumi Maegawa, Ruby May Andales, Ulf Skoglund, Akira Kamei 828-Pos Board B598 3D-STRUCTUAL MODELING OF MYOGENIC DIFFERENTIATION OF C2C12 MYOBLASTS BY ADVANCED ELECTRON MICROSCOPY AND LIGHT MI- CROSCOPY. Takako M. Ichinose, Sei Saitoh, Atsuko H. Iwane

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