Biophysical Society 62nd Annual Meeting | Program Guide

Board S69 RESOLVING THE MECHANISM OF ADHESION MEDIATED BY A NON- CLUSTERED DELTA-1 PROTOCADHERIN. Debadrita Modak (2002-Pos, B18) Board S70 LOCATION OF HYPERTROPHIC CARDIOMYOPATHY-CAUSING TROPONIN T MUTATIONS DETERMINES DEGREE OF MYOFILAMENT DYSFUNCTION. Maike Schuldt (1557-Pos, B466) Board S71 A LEVER-LIKE TRANSDUCTION PATHWAY FOR LONG-DISTANCE CHEMI- CAL- AND MECHANO-GATING OF THE MECHANOSENSITIVE PIEZO1 CHANNEL. Yanfeng Wang (576-Pos, B346) Board S72 EXPERIMENTAL AND COMPUTATIONAL STUDIES OF OBSCURIN’S FLEX- IBILITY. Jake Whitley (2013-Pos, B29) Membrane Biophysics Board S73 MULTISCALE SIMULATIONS OF MEMBRANE RECOGNITION BY LIPID KINASES. Sarah-Beth Amos (3042-Pos, B250) Board S74 LIPID BINDING AND LIPID-UPTAKE IN P-GLYCOPROTEIN: COMPARISON OF THE INWARD- AND OUTWARD-FACING CONFORMATION. Estefania Barreto-Ojeda (746-Pos, B516) Board S75 INVESTIGATING A DOMAIN I HYPOKALEMIC PERIODIC PARALYSIS MU- TATION IN HNAV1.4: A COMPUTATIONAL APPROACH. Landon Bayless-Edwards (3133-Pos, B341) Board S76 STRUCTURAL STUDIES OF MAGNESIUM TRANSPORTER CNNM. Yu Chen (2823-Pos, B31) Board S77 PHYSIOLOGICAL TRADEOFFS OF TTX RESISTANCE IN NA V 1.4: WHOLE CELL ELECTROPHYSIOLOGY AND TISSUE MYOGRAPHY REVEAL RE- DUCED TETRODOTOXICITY AT THE COST OF CHANNEL FUNCTION. Robert del Carlo (3132-Pos, B340) Board S78 ROLE OF AN INTRASUBUNIT CA 2+ BRIDGE DEPENDENT ACTIVATION OF BK CHANNELS. Alberto Gonzalez-Hernandez (2370-Pos, B386) Board S79 INVESTIGATING THE INTERACTIONS BETWEEN VEGFR2 AND EGFR. Hana Grubb (2291-Pos, B307) Board S80 FUNCTIONAL CHARACTERIZATION OF NOVEL PHOTO-SWITCHABLE NEUROMUSCULAR BLOCKERS. Clara Herrera-Arozamena (1490-Pos, B399)

Board S81 FLEXIBILITY OF A TRANSMEMBRANE HELIX UNDERLIES DRAMATIC REVERSAL OF NET ANESTHETIC EFFECTS IN A PENTAMERIC LIGAND- GATED ION CHANNEL. Stephanie Heusser (2414-Pos, B430) Board S82 OPTIMAL DESIGN OF AN AQUAPORIN LIPID MEMBRANE SYSTEM US- ING MOLECULAR DYNAMICS SIMULATION. Hyunki Kim (3028-Pos, B236) Board S83 EXPLORING A NOVEL OLIGOMERIZATION MECHANISM OF THERMO- STABLE DIRECT HEMOLYSIN, A PORE-FORMING PROTEIN. Nidhi Kundu (1986-Pos, B2) Board S84 SYNTHETIC BATRACHOTOXIN DERIVATIVES AS MOLECULAR PROBES OF VOLTAGE-GATED SODIUM ION CHANNEL FUNCTION. Timothy MacKenzie (3137-Pos, B345) Board S85 IDENTIFICATION OF POTENT AND SELECTIVE INHIBITORS TO INVESTI- GATE THE ROLE OF EPITHELIAL SODIUM CHANNELS IN NEURODEGEN- ERATION. Victoria Miller (3364-Pos, B572) Board S86 STRUCTURAL AND ENERGETIC DETAILS OF THE BINDING OF PTEN TO PHOSPHATIDYLINOSITOL PHOSPHATE-CONTAINING MEMBRANES THROUGH MOLECULAR SIMULATIONS. Fiona Naughton (1396-Pos, B305) Board S87 HEAT SENSITIVE GATING MECHANISM OF TRPV1 CHANNEL REVEALED BY MOLECULAR DYNAMICS SIMULATION. Soon Woo Park (2377-Pos, B393) Board S88 INTERACTION SITES OF SEROTONIN TYPE 3A INTRACELLULAR DOMAIN (5-HT 3A -ICD) WITH CHAPERON PROTEIN RIC-3. Elham Pirayesh (1497-Pos, B406) Board S89 RATIONAL DESIGN OF AGO-ALLOSTERIC SMALL MOLECULE OF GLP-1R. Tejashree Redij (286-Pos, B56) Board S90 DEVELOPMENT AND APPLICATION OF A PEPTIDE INHIBITOR-BOUND QUANTUM DOT TARGETING THE VOLTAGE-GATED POTASSIUM CHAN-

S U N D A Y

NEL KV1.3 IN THE OLFACTORY BULB. Austin Schwartz (1545-Pos, B454)

Board S91 EFFECTS OF 5-HT 3A

INTRACELLULAR DOMAIN MODIFICATIONS ON

OLIGOMERIZATION. Antonia Stuebler (1496-Pos, B405)

Board S92 CALCIUM-DEPENDENT REGULATION OF POTASSIUM CHANNELS IN CARDIAC ELECTROPHYSIOLOGY: A COMPUTATIONAL STUDY. Henry Sutanto (2340-Pos, B356)

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