Biophysical Society 62nd Annual Meeting | Program Guide

951-Plat 9:00 am HOW GLUT1 TRANSPORTER ACCOMPANIES GLUCOSE ALONG TRANS- PORT: A DETAILED ATOMISTIC VIEW OF THE MECHANISM. Matthieu Ng Fuk Chong, Lylia Challali, Sonia Abbar, Catherine Etchebest 952-Plat 9:15 am DISSECTING STEPS IN ATP-DRIVEN PROTEIN TRANSLOCATION THROUGH THE SECY TRANSLOCON ON SINGLE MOLECULE LEVEL.  Tomas Fessl 953-Plat 9:30 am FUNCTIONAL AND STRUCTURAL STUDIES OF INTERPLAY BETWEEN AN ABC TRANSPORTER AND ITS SURROUNDING MEMBRANE ENVIRON- MENT.  Su-Jin Paik , Alicia Damm, John Manzi, Maxime Dahan, Patricia Bassereau, Emmanuel Margeat, Daniel Levy 954-Plat 9:45 am Education Travel AwardeE ELECTROPHYSIOLOGICAL CHARACTERIZATION OF HYPERALDOSTERON- ISM-ASSOCIATED NA/K PUMP MUTATIONS.  Dylan J. Meyer , Craig Gatto, Pablo Artigas 955-Plat 10:00 am MECHANISTIC STUDIES OF THE KDP POTASSIUM TRANSPORT COMPLEX.  Marie E. Sweet , Paula Upla, Xihui Zhang, Bjørn P. Pedersen, David L. Stokes Platform Protein Structure and Conformation II 8:15 am–10:15 am, Esplanade, Room 153 Co-Chairs Jeliazko Jeliazkov, Johns Hopkins University Lauren Porter, HHMI 8:15 am ANALYSIS OF PROTEIN SEQUENCE AND STRUCTURAL CONSEQUENCES OF amINO ACID VARIANTS ASSOCIATED WITH AUTOIMMUNE INFLAMMA- TORY BOWEL DISEASE.  Chang Chen, Constance Jeffery 957-Plat 8:30 am EVOLUTION OF CDR H3 FLEXIBILITY AT AN IMMUNOMIC SCALE.  Jeliazko R. Jeliazkov , Adnan Slojka, Daisuke Kuroda, Nobuyuki Tsutchimu- ra, Kouhei Tsumoto, Naoki Katoh, Jeffrey J. Gray 958-Plat 8:45 am ANALYZING THE STRUCTURE AND SYMMETRY OF MEMBRANE PROTEINS THROUGH THE SYSTEMATIC ONLINE DATABASE ENCOMPASS.  Edoardo Sarti , Antoniya Aleksandrova, Lucy R. Forrest 959-Plat 9:00 am INACTIVATION MECHANISM OF PROTEIN KINASE A REVEALED BY MARKOV MODEL.  Yingjie Wang , Jonggul Kim, Cristina Olivieri, Jiali Gao, Gianluigi Veglia 960-Plat 9:15 am DYNAMICS AND INTERACTIONS OF PROTEINS AND METABOLITES IN CEL- LULAR CROWDING ENVIRONMENTS: ALL-ATOMMOLECULAR DYNAM- ICS STUDY OF PROTEINS AND METABOLITES IN CELLULAR CROWDING ENVIRONMENTS: ALL-ATOMMOLECULAR DYNAMICS STUDY.  Isseki Yu , Takaharu Mori, Tadashi Ando, Ryuhei Harada, Jaewoon Jung, Yuji Sugita, Michael Feig 961-Plat 9:30 am PROTEIN FOLD SWITCHING IS WIDESPREAD.  Lauren Porter , Loren Looger 962-Plat 9:45 am AUTOMATIC BUILDING OF PROTEIN ATOMIC MODELS FROM CRYO-EM MAPS.  Guillaume Bouvier , Benjamin Bardiaux, Michael Nilges 956-Plat

963-Plat 10:00 am QUANTITATIVE CHARACTERIZATION OF THE CONFORMATIONAL DYNAM- ICS OF THE UNBOUND LIPASE-SPECIFIC FOLDASE LIF BY MD SIMULATIONS AND FLUORESCENCE SPECTROSCOPY.  Neha Verma , Jakub Kubiak, Peter Dollinger, Filip Kovacic, Holger Gohlke, Claus Seidel, Karl-Erich Jaeger Platform

M O N D A Y

Bioengineering and Biomaterials 8:15 am–10:15 am, Esplanade, Room 154

Co-Chairs Meagan Small, University of Maryland, Baltimore Christine Selhuber-Unkel, University of Kiel, Germany 964-Plat 8:15 am

TAILORED MULTIVALENT BIOMOLECULES FOR AN OPTIMAL INTERACTION WITH INFLUENZA A VIRUS HEMAGGLUTININ–FROM IN SILICO MODELING TO IN VIVO VIRAL INFECTION INHIBITION.  Daniel Lauster , Victor Bandlow, Susanne Liese, Kai Ludwig, Marlena Stadtmüller, Simon Klenk, Sandra Sänger, Christoph Böttcher, Thorsten Wolff, Christian Hackenberg- er, Oliver Seitz, Roland Netz, Andreas Herrmann 965-Plat 8:30 am IMPARTING NONNATIVE GOLD BINDING FUNCTIONALITY BY BIOENGI- NEERING BACTERIAL FIMBRIAL TIP PROTEIN FIMH WITH GOLD BINDING PEPTIDES. Meagan C. Small , Jessica L. Terrell, Dimitra N. Stratis-Cullum, Margaret M. Hurley 966-Plat 8:45 am HIGH THROUGHPUT ELECTROPORATION SYSTEM FOR BIO-MOLECULE DELIVERY INTO ZEBRAFISH FOLLICLE.  Tayyebeh Saberbaghi , Ebrahim Ghafar-zadeh, Chun Peng 967-Plat 9:00 am DEFORMABILITY OF INDIVIDUAL CELLS PROBED BY ELECTRICAL AND OPTICAL SIGNALS.  Zuzanna S. Siwy , Preston Hinkle, Trisha M. Westerhof, Yinghua Qiu, David J. Mallin, Matthew L. Wallace, Chih-Yuan Lin, Edward L. Nelson, Peter Taborek 968-Plat 9:15 am FLUORESCENT NANOSENSORS FOR TWO-PHOTON INFRARED IMAG- ING OF DOPAMINE RELEASE IN BRAIN TISSUE.  Jackson T. Del Bonis- O’Donnell , Ralph Page, Abraham Beyene, Eric Tindall, Ian McFarlane, Markita Landry 969-Plat 9:30 am INTERCONNECTED MICROCHANNELS IN HYDROGELS TO CONTROL CELL ADHESION AND MECHANOTRANSDUCTION. Mohammadreza Taale, Christine Arndt, Christine Selhuber-Unkel 970-Plat 9:45 am AN EEL-INSPIRED ARTIFICIAL ELECTRIC ORGAN: 110 VOLTS FROMWATER AND SALT.  Anirvan Guha , Thomas B. H. Schroeder, Aaron Lamoureux, Gloria VanRenterghem, David Sept, Max Shtein, Jerry Yang, Michael Mayer 971-Plat 10:00 am WET ADHESIVE NANOMATERIALS INSPIRED BY THE BARNACLE ADHE- SIVE.  Christopher R. So , Elizabeth Yates, Luis Estrella, Ashley Schenck, Catherine Yip, Kathryn J. Wahl Platform

Protein-Nucleic Acid Interactions 8:15 am–10:15 am, Esplanade, Room 155

Co-Chairs Kalli Kappel, Stanford University Polly Fordyce, Stanford University

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