Biophysical Society 62nd Annual Meeting | Program Guide

Protein Structure and Conformation I (Boards B1–B30) 1092-Pos Board B1 CONSERVED DOMAIN ARCHITECTURE OF HUMAN BLM HELICASE MAIN- TAINS BALANCE BETWEEN D-LOOP DISRUPTION AND EXTENSION.  Gábor M. Harami , Yeonee Seol, János Pálinkás, Máté Gyimesi, Zoltán J. Kovács, Máté Martina, Anna Budai, Julianna B. Németh, Keir C. Neuman, Mihály Kovács 1094-Pos Board B3 RECQ HELICASE TRIGGERS A BINDING MODE CHANGE IN THE SSB-DNA COMPLEX EFFICIENTLY INITIATE DNA UNWINDING. Gábor M. Harami, Maria Mills, Yeonee Seol, Máté Gyimesi, Máté Martina, Zoltán J. Kovács, Mihaly Kovacs , Keir C. Neuman 1093-Pos Board B2 SECRET FROM THE ABYSS: STRUCTURES OF THE D-FAMILY DNA POLY- MERASE (POLD) REVEAL THAT DNA REPLICATION AND DNA TRANSCRIP- TION SHARE A JOINT EVOLUTIONARY HISTORY IN ARCHAEA. Pierre Raia, Pierre Béguin, Ghislaine Henneke, Marc Delarue, Ludovic Sauguet 1095-Pos Board B4 POTENTIAL DISRUPTION OF EBOLA VIRUS MATRIX BY GRAPHENE NANO- SHEETS. Rudramani Pokhrel , Jeevan GC, Nisha Bhattarai, Prem Chap- again, Bernard Gerstman 1096-Pos Board B5 TOWARD HIGH RESOLUTION STRUCTURES OF THE HIV-1 IN/LEDGF/DNA COMPLEX. Julien Batisse, Eduardo Bruch, Nicolas Levy, Benoit Maillot, Sylvia Eiler, Oyindamola Oladosu, Marc Ruff 1097-Pos Board B6 CAN SAXS TELL US WHETHER ANTIBODY SHAPE EVOLVES?  Rosaleen A. Calvert , Katy A. Doré, Brian J. Sutton, Andrew J. Beavil 1098-Pos Board B7 ACCOUNTING FOR SPECIFICITY AND CROSS-REACTIVITY IN T CELL RECEP- TOR MOLECULAR RECOGNITION. Brian M. Baker 1099-Pos Board B8 FLAVIVIRUS CAPSID PROTEIN BINDING TO HOST LIPID SYSTEMS. Ana S. Martins, André Nascimento, André F. Faustino, Filomena A. Carvalho, Nuno C. Santos, Ivo C. Martins 1100-Pos Board B9 NANOBODIES TARGETING NOROVIRUS CAPSID REVEAL FUNCTIONAL EPITOPES AND POTENTIAL MECHANISMS OF NEUTRALIZATION.  Anna D. Koromyslova , Grant S. Hansman 1101-Pos Board B10 MERCURY AND ALZHEIMERS DISEASE: HG(II) IONS DISPLAY SPECIFIC BINDING TO THE amYLOID-BETA PEPTIDE AND MODULATE ITS AGGREGA- TION. Sebastian Warmlander , Cecilia Wallin, Sabrina Sholts, Per Roos, Jyri Jarvet, Astrid Graslund 1102-Pos Board B11 CID Travel Awardee SPECTROSCOPIC STUDIES OF BUFFER AND METAL ION EFFECTS ON amYLOID-BETA PEPTIDE STRUCTURE AND AGGREGATION. Keyon Carter 1103-Pos Board B12 COMBINING DNP NMR WITH SEGMENTAL AND SPECIFIC LABELING TO STUDY THE QUATERNARY STRUCTURES OF YEAST PRION PROTEIN STRAINS. Yiling Xiao , Whitney Costello, Carla Madrid, Kendra Frederick 1104-Pos Board B13 International Travel Awardee UNDERSTANDING THE STRUCTURAL BASIS OF RECOGNITION BETWEEN PLASMODIUM FALCIPARUM AND HUMAN SUMOYLATION MACHIN- ERY.  Jai Shankar Singh , Vaibhav Kumar Shukla, Mansi Gujarati, Ram Kumar Mishra, Ashutosh Kumar

1105-Pos Board B14 STRUCTURAL BASIS OF AN ESSENTIAL INTERACTION BETWEEN DNAG AND DNAB IN MYCOBACTERIAL TUBERCULOSIS . Dhakaram P. Sharma , Ramachandran Vijayan, Arif Abdul Rehman, Samudrala Gourinath 1106-Pos Board B15 International Travel Awardee EVOLUTION OF ANTIBODY STRUCTURE AND FUNCTION THROUGH STUD- IES OF IGE AND IGM. Rosemary Nyamboya 1107-Pos Board B16 CPOW Travel Awardee SPECTROSCOPIC STUDY OF CU(II) BINDING TO THE LIGHT CHAIN 6AJL2 AND ITS EFFECT ON amYLOID FIBER FORMATION. Angel Pelaez-Aguilar, Carlos amero, Lina Rivillas-Acevedo 1108-Pos Board B17 ELECTROSTATIC INTERACTIONS AT THE DIMER INTERFACE STABILIZE THE E. COLI Β SLIDING CLAMP. Anirban Purohit 1109-Pos Board B18 DISSOCIATION OF FACTOR XIII HOMODIMER DURING ACTIVATION PRO- CESS: SOLUTION EVIDENCE WEIGHS IN ON DECADES-LONG DEBATE.  Boris Anokhin , Vilius Stribinskis, William Dean, Muriel Maurer 1110-Pos Board B19 STRUCTURE AND CONFORMATIONAL DYNAMICS OF THE SPLICING FACTOR HNRNP H. Liang-Yuan Chiu , Blanton S. Tolbert, Srinivasa Rao Penumutuchu 1111-Pos Board B20 AMYLOID BETA PEPTIDE AGGREGATION PROCESS IN THE PRESENCE OF SUGAR-BASED SURFACTANTS- CONFORMATIONAL AND STRUCTURAL STUDIES. Michalina Wilkowska , Weronika Andrzejewska, Ryszard Zieliński, Maciej Kozak 1112-Pos Board B21 MAPPING THE REGIONS IN PCNA THAT MEDIATE NUCLEOSOME ASSEM- BLY. Lynne Dieckman , Molly Carrig, Claire Embree, Kurt Shaffer, Hunter Board B22 TAU PEPTIDE INTERACTIONS WITH LIPID MEMBRANES: SECONDARY STRUCTURE ANALYSIS. Sam Ealy 1114-Pos Board B23 DECIPHERING THE INTERACTIONS BETWEEN AN ANTICANCER BACTERIO- CIN AND THE P53 DNA BINDING DOMAIN. Yongqi Huang , Jingjing Zhou, Xiyao Cheng, Zhengding Su 1115-Pos Board B24 MOTIF IV AND V OF ACTIVE DNA DEPENDENT ATPASE A DOMAIN, A SWI2/SNF2 PROTEIN, ARE REQUIRED FOR BOTH LIGAND BINDING AND CONFORMATIONAL INTEGRITY. Vijendra Arya , Rohini Muthuswami 1116-Pos Board B25 HUMAN NOROVIRUS INHIBITION THROUGH COMBINATION DRUG TREATMENT. Alessa Ringel , Turgay Kilic, Jessica Devant, Kerstin Ruoff, Anna Koromyslova, Alexander Hempelmann, Michelle Haas, Celina Geiß, Imme Roggenbach, Juliane Graf, Grant Hansman 1117-Pos Board B26 MONITORING OF ALZHEIMER’S amYLOID-Β PEPTIDE AGGREGATION VIA FLUORESCENCE CORRELATION SPECTROSCOPY AND TOTAL INTERNAL RE- FLECTION MICROSCOPY.  Jüri Jarvet , Astrid Gräslund, Ann Tiiman, Vladana Board B27 BIOCHEMICAL AND BIOPHYSICAL CHARACTERISATION OF INFLUENZA A VIRUS PROTEINS. Muhd Faiz-Hafiz Mohd Kipli , Jolyon Claridge, Jason Schnell VanDolah 1113-Pos Vukoevic 1118-Pos

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