Biophysical Society 63rd Annual Meeting | Program Guide

2160-Pos TRAVEL AWARDEE MOLECULAR DYNAMICS INVESTIGATION OF THE PHYSICAL BINDING OF THE NNK DIAZONIUM ION TO EXON 5 OF TP53. David M. Wahl , Christos Board B523

2146-Pos Board B509 THEORETICAL MODELING OF THE RNA-ENHANCED NTPASE ACTIVITY OF DENGUE AND ZIKA NS3 HELICASES. Russell B. Davidson , Martin McCul- lagh 2147-Pos Board B510 CONFORMATIONAL FLUCTUATIONS AND CHANGES OF SR-CA 2+ -ATPASE ON THE E1/E2 TRANSITION. Chigusa Kobayashi , Yasuhiro Matsunaga, Jaewoon Jung, Yuji Sugita 2148-Pos Board B511 UTILIZING UMBRELLA SAMPLING AND BROWNIAN DYNAMICS TO STUDY THE FUNCTIONAL AND DYNAMIC CHARACTERISTICS OF CARDIAC TROPO- NIN C.  Jacob D. Bowman , Steffen Lindert 2149-Pos Board B512 VIRTUAL SCREENING FINDS TROPONIN CALCIUM SENSITIZERS AND UM- BRELLA SAMPLING SIMULATIONS ELUCIDATE DIFFERENCES IN TROPONIN C ISOFORM AND MUTANT HYDROPHOBIC PATCH EXPOSURE. Jacob Bow- man, Melanie Aprahamian, Svetlana Tikunova, Jonathan P. Davis, Steffen Lindert 2150-Pos Board B513 HOW LIGAND BINDING ALTERS THE DYNAMICS OF TOLL-LIKE RECEPTOR 4 (TLR4) AND ITS CO-RECEPTOR MYELOID DIFFERENTIATION FACTOR 2 (MD-2): A MOLECULAR DYNAMICS SIMULATION. Alireza Tafazzol , Yong Duan 2151-Pos Board B514 ACTIVATION OF THE VOLTAGE GATED PROTON CHANNEL HV1: A CON- STANT PH MOLECULAR DYNAMICS STUDY.  Jack A. Henderson , Jana Shen 2152-Pos Board B515 EARLY TRANSLOCATION OF ANTHRAX LETHAL FACTOR: KINETICS FROM MOLECULAR DYNAMICS SIMULATIONS AND MILESTONING THEORY. Piao Ma , Alfredo E. Cardenas, Mangesh Chaudhari, Ron Elber, Susan L. Rempe 2153-Pos Board B516 CENP-A HIJACKS THE HISTONE CHAPERONE NETWORK IN CANCER--COM- PUTATIONAL INSIGHTS. Mary Pitman , Yamini Dalal, Garegin A. Papoian 2154-Pos Board B517 PROTEIN KINASE FREE ENERGY LANDSCAPES: THE ROLE OF THE ACTIVA- TION LOOP. Shima Arasteh , Peng He, Allan Haldane, Ronald M. Levy 2155-Pos Board B518 TRAVEL AWARDEE EXPLORATIONS OF DRUG TRANSPORT BY P-GLYCOPROTEIN USING MO- LECULAR DYNAMICS ENABLED BY HIGH RESOLUTION CRYSTAL STRUC- TURES. Lauren E. Ammerman , Pia D. Vogel, John G. Wise 2156-Pos Board B519 PEPTIDE BINDING INTERACTION BETWEEN ARKA AND ABP1SH3 USING MARKOV STATE MODELS. Henry Huang , Gabriella Gerlach 2157-Pos Board B520 EFFECT OF CAPSID TAIL ON SEMI-FLEXIBLE POLYMER PACKING INTO A CAPSID IN A CROWDED ENVIRONMENT. Nada Ahmed Alnaamani 2158-Pos Board B521 TRAVEL AWARDEE STRUCTURE AND DYNAMICS OF ALZHEIMER’S ASSOCIATED AMYLOID- BETA PEPTIDE. Thomas Löhr , Kai Kohlhoff, Gabriella Heller, Michele Vendruscolo 2159-Pos Board B522 INSIGHT INTO AMYLOID INTERACTIONS: MOLECULAR DYNAMICS SIMU- LATIONS OF MODEL PEPTIDE FRAGMENTS. Nicholas A. Cramer , Grant Kawecki, David R. Bevan, Anne M. Brown

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Deligkaris 2161-Pos

Board B524 MOLECULAR DYNAMICS SIMULATIONS USING ACCURATE CHARGE- CHARGE INTERACTIONS PREDICT UNEXPECTED PHASE BEHAVIORS OF DNA CONTROLLED BY EPIGENETIC MODIFICATIONS. Sunjoo You, Jejoong Yoo Optical Microscopy and Superresolution Imaging III (Boards B525 - B548) 2162-Pos Board B525 UNDERSTANDING CARDIAC TUBE FORMATION IN DEVELOPING DRO- SOPHILA EMBRYOS USING LIGHT SHEET MICROSCOPY AND CARDIAC DRUG SCREENING. Christopher Mj McFaul , Rodrigo Fernandez-Gonzalez, Christopher M. Yip 2163-Pos Board B526 PAIR CORRELATION ANALYSIS OF LOCALIZATION MICROSCOPY DATA WHEN SAMPLING DENSITY IS NOT UNIFORM. Thomas R. Shaw , Sarah A. Shelby, Sarah L. Veatch 2164-Pos Board B527 ACHIEVING AXIAL SUPER-RESOLUTION WITH THE TWO-PHOTON DUAL- COLOR Z-SCAN METHOD. Siddarth Reddy Karuka , Isaac Angert, John Kohler, G. W. Gant Luxton, Louis M. Mansky, Joachim D. Mueller 2165-Pos Board B528 TRAVEL AWARDEE DEVELOPMENT AND OPTIMIZATION OF THE Y-FAST:FLUOROGEN SYSTEM FOR SUPER-RESOLUTION IMAGING. Elizabeth M. Smith , Arnaud Gautier, Elias M. Puchner 2166-Pos Board B529 A NOVEL VIEWPOINT TO ANALYZE STRUCTURED ILLUMINATION MICROS- COPY (SIM) DATA.  Isotta Cainero , Simone Pelicci, Melody Di Bona, Alberto Diaspro, Luca Lanzano’ 2167-Pos Board B530 SINGLE-CELL CORRELATIONS OF INTRON, MRNA, AND PROTEIN CONTENT IN HUMAN IMMUNE-IMMUNE CELLS. Daniel Kalb , Samantha Adikari, Pulak Nath, Elizabeth Hong-Geller, James Werner 2168-Pos Board B531 OPTIMIZATION OF SINGLE MOLECULE PALM IMAGING CONDITIONS US- ING MEOS2. Ragnar Stefánsson 2169-Pos Board B532 IMAGING CANCER CELLS AND THEIR INTERACTIONS WITHIN 3D MI- CROENVIRONMENT - A QUANTITATIVE STUDY USING CRYO SOFT X-RAY TOMOGRAPHY.  Jian-Hua Chen , Axel Ekman, Venera Weinhardt, Gerry McDermott, Mark A. Le Gros, Carolyn A. Larabell 2170-Pos Board B533 SPATIAL CUMULANT ANALYSIS TO STUDY D2-LIKE DOPAMINE RECEP- TOR DYNAMICS ON PLASMA MEMBRANE. Daniel J. Foust , Alessandro Ustione, David W. Piston 2171-Pos Board B534 LIVE CELL SUPER-RESOLUTION IMAGING WITH RED-SHIFTED STATES OF CONVENTIONAL BODIPY FLUOROPHORES. Santosh Adhikari , Joe Moscatelli, Elias Puchner 2172-Pos Board B535 OPTIMIZING ASTIGMATISM FOR 3D STOCHASTIC OPTICAL RECONSTRUC- TION MICROSCOPY. Alondra Escobar , Christopher M. Yip

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