Biophysical Society 63rd Annual Meeting | Program Guide

Wednesday, March 6, 2019 Daily Program Summary All rooms are located in the Baltimore Convention Center unless noted otherwise.

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8:00 am-11:00 am New Council Meeting

Room 331

8:00 am-3:00 pm

Poster Viewing

Exhibit Hall

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Symposium: Mapping the Cell

Ballroom I

Chair: Raymond Stevens, University of Southern California CREATING AN IMAGE-BASED STEM CELL STATE SPACE. Rick Horwitz

8:15 am-10:15 am

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LINKING SYSTEMS WITH STRUCTURE: DERIVING MECHANISMS FROM LARGE-SCALE DATA SETS. Nevan Krogan SIMULTANEOUS CROSS-EVALUATION OF HETEROGENEOUS E. COLI DATASETS VIA MECHANISTIC SIMULATION. Markus Covert TOWARDS A MODEL OF THE HUMAN PANCREATIC BETA CELL. Raymond C. Stevens Chair: Joseph D. Puglisi, Stanford University CO-TRANSLATIONAL PROTEIN FOLDING AND INSERTION INTO THE MEMBRANE. Marina Rodnina HIGH-RESOLUTION 3D STRUCTURE DETERMINATION OF LARGE AND DYNAMIC MACROMOLECULAR COMPLEXES. Holger Stark UNTANGLING MESSENGER RNA STRUCTURE WITH DEAD-BOX RNA HELICASES. Elizabeth Tran DYNAMICS OF EUKARYOTIC TRANSLATION INITIATION. Joseph D. Puglisi Symposium: RNA

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Ballroom II

8:15 am-10:15 am

8:15 am-10:15 am Platform: TRP Channels

Ballroom III

8:15 am-10:15 am Platform: Intrinsically Disordered Proteins (IDP) and Aggregates III

Ballroom IV

8:15 am-10:15 am Platform: General Protein-Lipid Interactions

Room 307/308

8:15 am-10:15 am Platform: Actin Structure, Dynamics & Associated Proteins

Room 309/310

Room 314/315

8:15 am-10:15 am Platform: Protein Assemblies/Enzyme Function, Cofactors & Post-translational Modifications II

8:15 am-10:15 am Platform: Mechanosensation

Room 316/317

10:30 am-12:30 pm Poster Presentations and Late Posters

Exhibit Hall

Symposium: Membrane Organization and Sculpting by Proteins Chair: Jenny Hinshaw, NIH REVERSE TOPOLOGY MEMBRANE SCISSION BY THE ESCRTS. James H. Hurley

Ballroom I

1:00 pm-3:00 pm

MEMBRANE CURVATURE AND THE ABC TRANSPORTER BmrA: A YIN & YANG STORY. Patricia M. Bassereau STRUCTURAL DYNAMICS OF POTASSIUM CHANNEL MONOMER IN A MEMBRANE ENVIRONMENT AND TETRAMERIC ASSEMBLY. Benoit Roux CAPTURING SEQUENTIAL STEPS OF DYNAMIN-MEDIATED FISSION BY CRYO-EM. Jenny E. Hinshaw Chair: Shi-Qiang Wang, Peking University, China ACUTE LOSS OF CMYBP-C INDUCES AUTO-OSCILLATORY CONTRACTIONS IN PERMEABILIZED CARDIOMYOCYTES: IMPLICATIONS FOR REVERSE E-C COUPLING? Samantha P. Harris CBIN1: FROM T-TUBULE FOLDS TO DYAD ORGANIZATION, TO MICROPARTICLES AND CLINICAL USE. Robin Shaw REGULATION OF THE RYR2 CALCIUM RELEASE CHANNEL BY SPEG. Xander H.T. Wehrens CONJUNCT UPREGULATION OF JUNCTOPHILIN-2 AND CAVEOLIN-3 TRANSCRIPTION ENHANCED EXCITATION-CON- TRACTION COUPLING EFFICIENCY IN HIBERNATING GROUND SQUIRRELS. Shi-Qiang Wang Co-Chairs: Susan Marqusee, University of California, Berkeley Andrej Sali, University of California, San Francisco ADDING DIMENSIONS TO QUANTITATIVE INTRAVITAL IMAGING. Scott Fraser CRYO-EM STRUCTURE OF MICROBIAL NANOWIRES REVEALS STACKED HEMES THAT TRANSPORT ELECTRONS OVER MICRONS. Edward Egelman MOLECULAR MODELS OF BACTERIAL CELL ENVELOPES COME OF AGE: BOTH MEMBRANES AND THE CELL WALL ARE SIMULATED TO REVEAL NEW INSIGHTS. Syma Khalid MICROED: CONCEPTION, PRACTICE AND FUTURE OPPORTUNITIES. Tamir Gonen Symposium: Molecular and Transcriptional Regulation of Cardiac E-C Coupling New and Notable

Ballroom II

1:00 pm-3:00 pm

Ballroom III

1:00 pm-3:00 pm

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