Biophysical Society 63rd Annual Meeting | Program Guide

2277-Plat 9:15 am ENANTIOMERIC AΒ PEPTIDES INHIBIT THE FLUID SHEAR STRESS RE- SPONSE OF PIEZO1.  Philip A. Gottlieb , Mohammed M. Maneshi, Freder- ick Sachs, Susan Z. Hua 2278-Plat 9:30 am PIEZO1 MEDIATED CA 2+ SIGNALING CAUSES NUCLEAR SHRINKAGE UNDER FLUID SHEAR STRESS.  Deekshitha Jetta, Philip A. Gottlieb, Frederick Sachs, Susan Z. Hua 2279-Plat 9:45 am STRUCTURAL RELATIONSHIP BETWEEN THE PUTATIVE HAIR CELL MECHA- NOTRANSDUCTION CHANNEL TMC1 AND TMEM16 PROTEINS.  Angela Ballesteros Morcillo , Maria Cristina Fenollar-Ferrer, Kenton J. Swartz 2280-Plat 10:00 am CYSTEINE SUBSTITUTION REVEALS THE PORE-FORMING REGION OF TMC1 IN HAIR CELL SENSORY TRANSDUCTION CHANNELS.  Bifeng Pan, Nurunisa Akyuz, Xiao-Ping Liu, Yukako Asai, Carl Nist-Lund, Kiyoto Kurima, Bruce Derfler, Bence György, Walrati Limapichat, Sanket Walujkar, Lahiru Wimalasena, Marcos Sotomayor, David Corey, Jeffrey R. Holt Poster Presentations and Late Posters 10:30 am - 12:30 pm, Exhibit Hall Symposium Membrane Organization and Sculpting by Proteins 1:00 pm - 3:00 pm, Ballroom I Chair Jenny Hinshaw, NIH 2281-Symp 1:00 pm REVERSE TOPOLOGY MEMBRANE SCISSION BY THE ESCRTS.  James H. Hurley 2282-Symp 1:30 pm MEMBRANE CURVATURE AND THE ABC TRANSPORTER BMRA: A YIN & YANG STORY.  Patricia M. Bassereau , Ajay K. Mahalka, Su-Jin Paik, Giovanni Manzi, Andrew Callan-Jones, Daniel Levy 2283-Symp 2:00 pm STRUCTURAL DYNAMICS OF POTASSIUM CHANNEL MONOMER IN A MEMBRANE ENVIRONMENT AND TETRAMERIC ASSEMBLY.  Benoit Roux , Kevin Song, Young Hoon Koh, Eduardo Perozo, Tobin R. Sosnick 2284-Symp 2:30 pm CAPTURING SEQUENTIAL STEPS OF DYNAMIN-MEDIATED FISSION BY CRYO-EM.  Jenny E. Hinshaw , Leopold Kong, Kem A. Sochacki, Huaibin Wang, Bertram J. Canagarajah, Andrew D. Kehr, William J. Rice, Marie- Paule Strub, Justin W. Taraska Symposium Molecular and Transcriptional Regulation of

2266-Plat 8:30 am SUPERRESOLUTION IMAGING OF AMYLOID STRUCTURES OVER EX- TENDED TIMES USING TRANSIENT BINDING OF SINGLE THIOFLAVIN T MOLECULES.  Kevin Spehar, Tianben Ding, Yuanzi Sun, Niraja Kedia, Jin Lu, George R. Nahass, Matthew D. Lew, Jan Bieschke 2267-Plat 8:45 am IN VITRO STUDY OF THE EFFECT OF INSULIN ON AMYLOID Β-PROTEIN AS- SEMBLY AND TOXICITY.  Kaho Long , Thomas L. Williams, Brigita Urbanc 2268-Plat 9:00 am TRAVEL AWARDEE MULTIMERIC PROTEINS REVERSIBLY FORM CONDENSATES UPON OS- MOTIC COMPRESSION.  Ameya P. Jalihal 2269-Plat 9:15 am PHOTONIC PLATFORM FOR DETAILED PHYSICAL CHARACTERIZATION OF LIQUID PROTEIN DROPLETS.  Gheorghe Cojoc , Timon Beck, Saeed Ahmed, Titus Franzmann, Paul Müller, Mirjam Schürmann, Raimund Schlüβler, Kyoohyun Kim, Elisabeth Fischer-Friedrich, Simon Alberti, Jochen Guck 2270-Plat 9:30 am TRAVEL AWARDEE DISSECTION OF PROTEIN FUNCTION WITHIN A BACTERIAL BIOMOLECU- LAR CONDENSATE BY IN VITRO RECONSTITUTION.  Saumya Saurabh , Lucy Shapiro 2271-Plat 9:45 am EFFECT OF RESULTANT DIPOLE MOMENT ON MECHANICAL STABILITY OF PROTEIN-PEPTIDE COMPLEXES. Maksim Kouza, Anirban Banerji, Andrzej Kolinski, Irina Buhimschi, Andrzej Kloczkowski 2272-Plat 10:00 am COARSE-GRAINED AND ATOMISTIC SIMULATIONS OF THE MATURE HIV CAPSID AND RELATED RESTRICTION FACTORS.  Alvin Yu , Barbie K. Ganser- Pornillos, Owen Pornillos, Gregory A. Voth Platform Mechanosensation 8:15 am - 10:15 am, Room 316/317 Co-Chairs Jeffrey Holt, Harvard Medical School Amanda Buyan, Australian National University, Australia 2273-Plat 8:15 am TRAVEL AWARDEE HIGH-RESOLUTION STRUCTURES OF MSCS IN A LIPID BILAYER: REINTER- PRETING “FORCE FROM LIPIDS” ACTIVATION IN MECHANOSENSITIVE CHANNELS.  Bharat Reddy , Allen Lu, Navid Bavi, Allen Hsu, Mario Borg- nia, Eduardo Perozo 2274-Plat 8:30 am STRUCTURES AND SIMULATIONS OF MEMBRANE ADJACENT FRAGMENTS OF PROTOCADHERIN-15.  Pedro De-la-Torre, Yoshie Narui , Deepanshu Choudhary, Raul Araya-Secchi, Marcos Sotomayor 2275-Plat 8:45 am UNDERSTANDING PIEZO1’S RELATIONSHIP WITH LIPIDS.  Amanda Buyan , Charles D. Cox, Jonathan Barnoud, Boris Martinac, Siewert-Jan Marrink, 9:00 am DIETARY FATTY ACIDS FINE-TUNE PIEZO1 ACTIVITY.  Luis O. Romero , Ale- jandro Mata-Daboin, AndrewMassey, Francisco J. Sierra Valdez, Chauhan C. Subhash, Julio F. Cordero-Morales, Valeria Vasquez Ben Corry 2276-Plat

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Cardiac E-C Coupling 1:00 pm - 3:00 pm, Ballroom II

Chair Shi-Qiang Wang, Peking University, China 2285-Symp 1:00 pm

ACUTE LOSS OF CMYBP-C INDUCES AUTO-OSCILLATORY CONTRACTIONS IN PERMEABILIZED CARDIOMYOCYTES: IMPLICATIONS FOR REVERSE E-C COUPLING?  Samantha P. Harris 2286-Symp 1:30 pm CBIN1: FROM T-TUBULE FOLDS TO DYAD ORGANIZATION, TO MICROPAR- TICLES AND CLINICAL USE.  Robin Shaw

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