Biophysical Society 63rd Annual Meeting | Program Guide

2497-Pos Board B169 NMR STUDIES OF CONFORMATIONAL SELECTION OF HNRNP H ON RNA RECOGNITION AND ITS INTERACTION WITH THE HIV EXONIC SPLICING SILENCER ESS2P RNA. Liang-Yuan Chiu , Srinivas Penumutchu, Niyati Jain, Andrew Sugarman, Blanton S. Tolbert 2498-Pos Board B170 USING SINGLE MOLECULE METHODS TO STUDY MECHANISMS OF SITE SPECIFIC DNA CLEAVAGE. Allen C. Price , Stephen D. Parziale, Karissa Mehrtens, Anna D. Ware, Emily K. Matozel, Nathaniel Dale 2499-Pos Board B171 THE ROLE OF INTERFACIAL HYDRATION IN THE TRANSCRIPTION FACTOR PU.1/DNA COMPLEX. Amanda V. Albrecht , Hye Mi Kim, Gregory M. K. Poon 2500-Pos Board B172 CRYO-EM STRUCTURE OF THE P-ELEMENT TRANSPOSASE STRAND- TRANSFER COMPLEX. Elizabeth H. Kellogg , George Ghanim, Eva Nogales, Donald C. Rio 2501-Pos Board B173 FUNCTIONAL IMPLICATIONS OF THE RECQ HELICASE - TOPOISOMERASE III - SSB COMPLEX: INSIGHTS FROM SINGLE MOLECULE MEASURE- MENTS. K. Maria Mills , Yeonee Seol, Keir C. Neuman 2502-Pos Board B174 ESTABLISHING A SINGLE-MOLECULE FRET SYSTEM FOR STUDYING DNA- PROTEIN INTERACTIONS. Dacheng Zhao , Ishita Mukerji, Candice Etson 2503-Pos Board B175 COHESIN SA2 AND EWSR1 IN R-LOOP REGULATION. Hong Wang , Ashwin Ghadiyaram, Hai Pan, Yanlin Fan, Parminder Kaur, Aparna Gorthi, Robert Riehn, Alexander J.R. Bishop, Yizhi Jane Tao 2504-Pos Board B176 CHARACTERIZATION OF THE INTERACTIONS OF FRAGILE-X MENTAL RE- TARDATION PROTEIN WITH C9ORF72 REPEAT EXPANDED RNA. Kendy A. Pellegrene , Mihaela Rita Mihailescu, Jeffrey D. Evanseck 2505-Pos Board B177 SINGLE-MOLECULE STUDY OF TRF2 MEDIATED DNA COMPACTION USING PHYSIOLOGICALLY RELEVANT LONG TELOMERIC DNA. Parminder Kaur , Ryan Barnes, Hai Pan, Patricia Opresko, Robert Riehn, Hong Wang 2506-Pos Board B178 STRUCTURAL REARRANGEMENT OF DNA FOR CRISPR-CAS9 NUCLEASE SPECIFICITY REGULATED BY THE REC2 DOMAIN. Keewon Sung , Jinho Park, Younggyu Kim, Nam Ki Lee, Seong Keun Kim 2507-Pos Board B179 ALPHA-SYNUCLEIN BINDS TO DNA AND MODULATES ITS PHYSICAL PROPERTIES. Kai Jiang , Sandra Rocha, Alvina Westling, Sriram KK, Kevin D. Dorfman, Pernilla Wittung-Stafshede, Fredrik Westerlund 2508-Pos Board B180 SIMULATION OF H2A.B CONTAINING HISTONE VARIANT NUCLEO- SOME. Havva Kohestani , Jeffery M. Wereszczynski 2509-Pos Board B181 QUANTIFYING ANTICANCER DRUG DOXORUBICIN BINDING TO DNA US- ING OPTICAL TWEEZERS. Zachary Ells , Brian Dolle, Thayaparan Paramana- than

2484-Pos Board B156 CPG METHYLATION OF THE C9ORF72 NUCLEOTIDE REPEAT EXPANSION ALTERS G-QUADRUPLEX TOPOLOGICAL DISTRIBUTION. Kadir Ozcan , Aaron Haeusler Protein-Nucleic Acid Interactions II (Boards B157 - B181) 2485-Pos Board B157 CELLULAR DISTRIBUTION AND DIFFUSIVITY OF HFQ WITH INTERACTING RNAS. Seongjin Park , Karine Prévost, Matt Reyer, Emily Heideman, Wei Liu, Eric Massé, Jingyi Fei 2486-Pos Board B158 STRUCTURAL CHARACTERIZATION OF A PEPTIDE DERIVED FROM A LAB- EVOLVED PROTEIN THAT TARGETS HIV-1 TAR RNA. Sai Shashank Chavali , Ivan Belashov, Jermaine Jenkins, Joseph Wedekind 2487-Pos Board B159 NUCLEOTIDE-DEPENDENT STABILITY OF NUCLEOSOME-CHD1 COMPLEX- ES. Samaneh Ghassabi Kondalaji , Ren Ren, Ilana M. Nodelman, Gregory D. Bowman 2488-Pos Board B160 A HIGH-THROUGHPUT PLATFORM FOR PROBING MECHANISMS OF TRANSCRIPTION FACTOR-DNA BINDING. Arjun Aditham , Polly M. Fordyce 2489-Pos Board B161 CAENORHABDITIS ELEGANS MORC-1 TOPOLOGICALLY TRAPS AND COM- PACTS DNA. HyeongJun Kim , Linda Yen, Somsakul Wongpalee, Joseph Loparo, Steve Jacobsen 2490-Pos Board B162 AN EFFECTIVE SCORING FUNCTION WITH ATOMIC AND COARSE-GRAINED HYBRID REPRESENTATION FOR PROTEIN-RNA INTERACTIONS. Jiahua He, Shengyou Huang 2491-Pos Board B163 INVESTIGATING THE DNA BINDING ACTIVITY OF THE POLYBROMO-1 BROMODOMAINS. Saumya M. De Silva , Yangtian Shangguan, Tyler M. Weaver, Brianna E. Lupo, Catherine A. Musselman 2492-Pos Board B164 DETERMINATION OF THE MECHANISM OF RNA REGULATION BY CPSF30 UTILIZING BOTH BIOPHYSICAL AND STRUCTURAL APPROACHES.  Jordan D. Pritts , Abdulafeez A. Oluyadi, Daniel Deredge, Patrick L. Wintrode, Sarah L. J. Michel 2493-Pos Board B165 RNA G-QUADRUPLEX IS RESOLVED BY REPETITIVE AND ATP DEPENDENT MECHANISM OF DHX36. Ramreddy Tippana , Michael C. Chen, Natalia A. Demeshkina, Adrian R. Ferré-D’Amaré, SuA Myong 2494-Pos Board B166 DEEP LEARNING MODELS EXPLORE THE STRUCTURAL EFFECTS OF TRAN- SCRIPTION FACTOR-DNA COMPLEXES ON BINDING SPECIFICITY. Tyler C. Shimko , Polly M. Fordyce 2495-Pos Board B167 RRM2 OF CELF1 PROTEIN FROM PLASMODIUM FALCIPARUM PREFEREN- TIALLY BINDS TO UG REPEATS RNA. Garima Verma , Neel Sarovar Bhavesh 2496-Pos Board B168 SINGLE-STRANDED DNA BINDING AND CROSSLINKING ACTIVITIES OF THE VIRAL RESTRICTION FACTOR APOBEC3G CHARACTERIZED BY FORCE SPECTROSCOPY .  Ioulia F. Rouzina , Michael Morse, Nabuan Naufer, Yuq- ing Feng, Linda Chelico, Mark C. Williams

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