Biophysical Society 63rd Annual Meeting | Program Guide

372-Pos Board B147 AFM SHOWS THAT HUMAN CTIP FORMS A TETRAMERIC DUMBBELL- SHAPED PARTICLE WHICH BINDS AND BRIDGES DNA ENDS.  Alejandro Martin-Gonzalez , Oliver Wilkinson, Hae Joo Kang, Sarah Northall, Dale Wigley, Mark S. Dillingham, Fernando Moreno-Herrero 373-Pos Board B148 NOVEL ASSAY RESOLVES D-LOOP PROCESSING PATHWAYS BY E. COLI RECQ AND HUMAN BLM HELICASES. Gabor M. Harami , Janos Palinkas, Yeonee Seol, Mate Gyimesi, Zoltan J. Kovacs, Keir C. Neuman, Mihaly Kovacs 374-Pos Board B149 MECHANISM OF SSB DISPLACEMENT BY REPLICATIVE DNA POLYMERASES DURING LAGGING STRAND SYNTHESIS. Fernando Cerron, Grzegorz L. Ciesielski, Laurie S. Kaguni, Francisco J. Cao, Borja Ibarra 375-Pos Board B150 SINGLE-MOLECULE MOVIES OF THE INTERPLAY BETWEEN DNA POLY- MERASE AND SINGLE STRAND DNA BINDING (SSB) PROTEIN. Longfu Xu , Julia Bakx, Seyda Acar, Andreas Biebricher, Erwin J. Peterman, Gijs J. Wuite 376-Pos Board B151 ELUCIDATION OF THE ROLE OF THE INTERACTION BETWEEN RECQ HELICASE AND SSB PROTEIN. Gabor M. Harami, K. Maria Mills, Zoltan J. Kovacs, Yeonee Seol, Veronika Barath, Julianna B. Nemeth, Hajnalka Harami-Papp, Keir C. Neuman, Mihaly Kovacs 377-Pos Board B152 NOVEL CONFORMATIONALLY-TAUTOMERIC PROPERTIES OF THE BIOLOGI- CALLY IMPORTANT AT DNA BASE PAIRS. Ol’ha Brovarets’ , Kostiantyn Tsiupa 378-Pos Board B153 MUTS HOMOLOG SLIDING CLAMPS SHIELD THE DNA FROM BINDING PROTEINS.  Jeungphill Hanne , Brooke M Britton, Jonghyun Park, Jiaquan Liu, Juana Martin-Lopez, Nathan Jones, Matthew Schoffner, Piotr Klajner, Ralf Bundschuh, Jong-Bong Lee, Richard Fishel 379-Pos Board B154 SINGLE-MOLECULE STUDIES REVEAL NEW REPLICATION REACTIVATION PATHWAYS OF BACTERIOPHAGE T7. Bo Sun , Michelle D. Wang 380-Pos Board B155 NANOPORE DETECTS COMPROMISE BETWEEN SPEED AND PROCES- SIVITY OF PCRA HELICASE. Momcilo Gavrilov , Ram Tippana, Dmitriy Bobrovnikov, Taekjip Ha 381-Pos Board B156 REPLISOME PRESERVATION BY A SINGLE-STRANDED DNA GATE IN THE CMG HELICASE. Michael R. Wasserman , Grant D. Schauer, Michael E. O’Donnell, Shixin Liu 382-Pos Board B157 TRAVEL AWARDEE A NEW DNA INVERSION MECHANISM: RECOMBINATION OF THE DNA FOLDBACK INTERCOIL STRUCTURE. Byung Ho Lee , Soojin Jo, Hyunki Kim, Sung Ha Park, Byung-Dong Kim, Moon Ki Kim 383-Pos Board B158 EXOG DISPLAYS 5ʹ-EXONUCLEASE ACTIVITY ON BOTH SSDNA AND SS- RNA. Anna Karlowicz , Michal R. Szymanski 384-Pos Board B159 BIOPHYSICAL CHARACTERIZATION OF FULL LENGTH EXOG A HUMAN MI- TOCHONDRIAL INNER MEMBRANE NUCLEASE. Andrzej B. Dubiel , Michal R. Szymanski 385-Pos Board B160 ROLE OF MIS LOCALIZATION OF DNA REPAIR FACTORS IN CELL CYCLE AR- REST. Manasvita Vashisth , Sangkyun Cho, Dennis Discher

358-Pos Board B133 MULTI-SCALE SIMULATION OF THE CHROMATIN FIBER TO ELUCIDATE OCT4 GENE REPRESSION. Michael R. Williams , Dmitri Kireev 359-Pos Board B134 SURFACE FLUCTUATIONS AND COALESCENCE OF NUCLEOLAR DROPLETS IN THE HUMAN CELL NUCLEUS. Christina M. Caragine , Shannon Haley, Alexandra Zidovska 360-Pos Board B135 A PLATFORM FOR INVESTIGATING NUCLEAR ORGANIZATION AND ITS CHANGES DURING HUMAN IPSC DIFFERENTIATION. Susanne M. Rafelski 361-Pos Board B136 INTENSITY SORTED FLUORESCENCE CORRELATION SPECTROSCOPY: A NOVEL METHOD TO PROBE NUCLEAR DYNAMICS AND CHROMATIN ORGANIZATION IN LIVING CELLS. Melody Di Bona , Simone Pelicci, Isotta Cainero, Giuseppe Vicidomini, Davide Mazza, Michael A. Mancini, Alberto Diaspro, Luca Lanzano’ 362-Pos Board B137 EFFECT OF DIFFERENT TRANSCRIPTIONAL STATES ON THE SINGLE GENE DYNAMICS. Fang-Yi Chu , Alexandra Zidovska 363-Pos Board B138 DYNAMICAL SIGNATURES OF LOCAL DNA DAMAGE IN LIVE CELLS.  Jonah Eaton 364-Pos Board B139 DESTABILIZING NUCLEOSOMES AND THE ROLE OF HMGB PROTEINS.  Micah J. McCauley , Ran Huo, Emily Navarrete, Nicole Becker, Qi Hu, Mol- ly Nelson Holte, Uma Muthurajan, Ioulia Rouzina, Karolin Luger, Georges Mer, L. James Maher III, Nathan Israeloff, Mark C. Williams 365-Pos Board B140 CHROMATIN FOLDING HETEROGENEITY INFERRED FROM HIGH-RESOLU- TION NUCLEOSOME STRUCTURES. Stefjord Todolli , John Yager, Wilma K. Olson 366-Pos Board B141 HISTONE TAIL-DNA INTERACTIONS: CHARGE REGULATION AND SE- QUENCE SPECIFICITY. Raju Timsina , Xiangyun Qiu 367-Pos Board B142 MANY-BODY CHROMATIN INTERACTIONS IN SUPER-ENHANCER TADS. Alan Perez-Rathke , Qiu Sun, Valentina Boeva, Jie Liang 368-Pos Board B143 QUANTITATIVE MEASUREMENT OF NUCLEOSOME OCCUPANCY AND DNA ACCESSIBILITY. Razvan V. Chereji , Terri D. Bryson, Steven Henikoff 369-Pos Board B144 THE CHROMOSOME’S FIGHT AGAINST DISORDER IN E. COLI.  Christopher H. Bohrer , Elijah Roberts, Jie Xiao DNA Replication, Recombination, and Repair (Boards B145 - B166) 370-Pos Board B145 DNA MISMATCH REPAIR RELIES ENTIRELY ON STOCHASTIC TRANSAC- TIONS.  Jiaquan Liu , Ryang-Geun Lee, Brooke Britton, James London, Jeungphill Hanne, Jong-Bong Lee, Richard Fishel 371-Pos Board B146 DECIPHERING THE ESSENTIAL INTERACTION BETWEEN PRIMASE AND HELICASE IN MYCOBACTERIUM TUBERCULOSIS . Dhakaram P. Sharma , Ramachandran Vijayan, Syed Arif Abdul Rehman, Samudrala Gourinath

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