Biophysical Society 63rd Annual Meeting | Program Guide

Monday, March 4 Graduate Student Breakfast 7:30 am - 8:30 am, Room 321/322/323

Platform Protein-Small Molecule Interactions 8:15 am - 10:15 am, Ballroom III

M O N D A Y

Co-Chairs Alex Dickson, Michigan State University Rezvan Shahoei, University of Illinois at Urbana-Champaign 749-Plat 8:15 am MAPPING LIGAND BINDING LANDSCAPES USING WEIGHTED ENSEMBLES OF TRAJECTORIES.  Alex Dickson 750-Plat 8:30 am THE RELEVANCE OF CONFORMATIONAL ENTROPY FOR PROTEIN LIGAND INTERACTIONS: THE CASE OF BIOTIN AND STREPTAVIDIN. Mona Sarter , Andreas M. Stadler, Doreen Niether, Bernd W. Koenig, Michaela Zamponi, Lohstroh Wiebke, Simon Wiegand, Joerg Fitter 751-Plat 8:45 am STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF PERIPLASMIC SIALIC ACID BINDING PROTEINS FROM PATHOGENIC BACTERIA.  Thanuja Gangi Setty , Ramaswamy S 752-Plat 9:00 am MECHANICAL STRENGTH OF CATCH BOND FORMING FIMH AND MAN- NOSE.  Laura A. Carlucci , Keith Johnson, Wendy E. Thomas 753-Plat 9:15 am MENTHOL BINDS TO EXTRACELLULAR AND TRANSMEMBRANE DOMAINS OF THE HUMAN Α4Β2 NICOTINIC RECEPTOR.  Rezvan Shahoei , Emad Tajkhorshid 754-Plat 9:30 am MOLECULAR DETERMINANTS OF NON-OXIME BISPYRIDINIUM ACTIVITY AT ADULTS MUSCLE NACHRS. Max Epstein 755-Plat 9:45 am TARGETING THE MRNAS TRANSLATION PROCESS: A NOVEL THEORETICAL BASED APPROACH TO DESIGN TAILORED ANTICANCER AGENTS.  Daniele Di Marino , Stefano Raniolo, Alessandro Gori, Vittorio Limongelli 756-Plat 10:00 am PROTEIN DATABANK SURVEY HINTS INTO THE EMERGENCE OF PROTEIN- ADENINE RECOGNITION IN EVOLUTION.  Aya Narunsky, Ron Solan, amir Kessel, Rachel Kolodny, Nir Ben-Tal Platform Excitation-Contraction Coupling/Cardiac and Skeletal Muscle Electrophysiology II 8:15 am - 10:15 am, Ballroom IV Co-Chairs Sabine Lotteau, Smidt Heart Institute Filip Van Petegem, University of British Columbia, Canada 757-Plat 8:15 am L-TYPE CALCIUM CHANNELS ARE A MAJOR SOURCE OF PLASMALEMMEL CALCIUM INFLUX FOR DROSOPHILA CARDIOMYOCYTES.  Worawan B. Limpitikul , Meera C. Viswanathan, Brian O’Rourke, David T. Yue, Anthony Cammarato 758-Plat 8:30 am EFFICIENT HIGH-THROUGHPUT SCREENING FOR TYPE 1 RYANODINE RECEPTOR INHIBITORS USING ER CA 2+ MEASUREMENTS.  Takashi Murayama , Nagomi Kurebayashi, Mari Yuasa-Ishigami, Shuichi Mori, Haruo Ogawa, Junji Suzuki, Kazunori Kanemaru, Masamitsu Iino, Hiroyuki Kagechika, Takashi Sakurai

This breakfast presents an opportunity for graduate student Annual Meeting attendees to meet and discuss the issues they face in their cur- rent career stage. Limited to the first 100 attendees. Speakers Lamar Mair, Weinberg Medical Physics Frank Sachse, University of Utah Registration/Exhibitor Registration 7:30 am - 5:00 pm, Charles Street Lobby Poster Viewing 8:00 am - 10:00 pm, Exhibit Hall Symposium Large Macromolecular Machines in the Cell 8:15 am - 10:15 am, Ballroom I Chair Titia Sixma, Netherlands Cancer Institute, The Netherlands 743-Symp 8:15 am CRYO-EM STRUCTURE OF HUMAN TELOMERASE AND NEW INSIGHT INTO ITS ASSEMBLY AND FUNCTION.  Kelly THD Nguyen , Jane Tam, Robert Alexander Wu, Basil J. Greber, Eva Nogales, Kathleen Collins 744-Symp 8:45 am HIGH-RESOLUTION MODELING AND SIMULATION OF CELLULAR STRUC- TURES AND PROCESSES, ONE ATOM AT A TIME.  Emad Tajkhorshid 745-Symp 9:15 am STRUCTURE-FUNCTION MAPPING OF THE NUCLEAR PORE COMPLEX.  Michael P. Rout 746-Symp 9:45 am STEPPING THROUGH DNA MISMATCH REPAIR INITIATION.  Rafael Fernan- dez-Leiro, Doreth Bhairosing-Kok, Flora Groothuizen, Laffeber Charlie, Joyce H. Lebbink, Peter Friedhoff, Meindert Lamers, Titia K. Sixma Symposium Biological Membranes and Vesicles 8:15 am - 10:15 am, Ballroom II Chair John Briggs, MRC Laboratory of Molecular Biology, United Kingdom No Abstract 8:15 am STRUCTURAL CELL BIOLOGY OF VIRUS-HOST INTERACTIONS.  Kay Grünewald 747-Symp 8:45 am UNCOVERING THE MECHANISMS OF CLATHRIN-MEDIATED ENDOCYTOSIS USING QUANTITATIVE BIOLOGY APPROACHES.  Julien Berro 748-Symp 9:15 am CROWDING IN THE CELLULAR CONTEXT: TALES OF CLUSTERS AND DYNAMICS. Michael Feig No Abstract 9:45 am REVEALING THE STRUCTURES OF TRAFFICKING VESICLES AND ENVEL- OPED VIRUSES USING CRYO-ELECTRON TOMOGRAPHY.  John Briggs

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