Biophysical Society 63rd Annual Meeting | Program Guide

Protein Structure and Conformation II (Boards B1 - B35) 899-Pos Board B1 MOLECULAR BASIS OF THE MARBURG VIRUS PROTEIN VP24 INTER- ACTIONS WITH HUMAN KEAP1. Nisha Bhattarai , Prem P. Chapagain, Bernard Gerstman 900-Pos Board B2 SOLUTION NMR STRUCTURE OF THE GTPASE ACTIVATING (GAP) DOMAIN OF VOPE, A VIBRIO CHOLERAE T3SS EFFECTOR PROTEIN. Kyle P. Smith , Woonghee Lee, Marco Tonelli, Priscilla S-W Yeung 901-Pos Board B3 CHARACTERIZATION AND IRON BINDING DYNAMICS OF HAEMOPHILUS INFLUENZAE FERRIC BINDING PROTEIN. Goksin Liu , Ezgi Altun, S. Mert Unal, Canan Atilgan, Zehra Sayers 902-Pos Board B4 DESIGNING SUPERHYDROPHILIC, DISORDERED PEPTIDES TO IMPROVE THE STABILITY AND EFFICACY OF PROTEIN THERAPEUTICS.  Joshua Smith , Patrick McMullen, Zhefan Yuan, Shaoyi Jiang, Jim Pfaendtner 903-Pos Board B5 SYSTEMATIC ANALYSIS OF INTERNAL HYDRATION IN A PROTEIN. Anne M. Rice , Jaime L. Schlessman, Bertrand Garcia-Moreno 904-Pos Board B6 MARKOV MODELS OF FUNCTIONAL DYNAMICS OF HISTONE LYSINE METHYLTRANSFERASES BY MILLISECOND-TIMESCALE MOLECULAR SIMU- LATION AND CHEMICAL PROBING. Rafal P. Wiewiora , Shi Chen, Minkui Luo, John D. Chodera 905-Pos Board B7 STRUCTURAL MODULATION OF RYR1 BY MGATP AND FREE MG 2+ IN LIPID MEMBRANE USING CRYOEM. Ashok R. Nayak , Alex H. Will, Joshua Lobo, Pablo C. Hartmann, Montserrat Samso 906-Pos Board B8 CLASSIFYING OF ARRHYTHMOGENIC CARDIOMYOPATHY-LINKED DESMO- PLAKIN VARIANTS THROUGH MOLECULAR MECHANISMS OF PATHOGE- NICITY. Tyler L. Stevens , Heather Manring, Taylor Albertelli, Ronald Ng, Nathan T. Wright, Stuart Campbell, Maegen Ackermann 907-Pos Board B9 CHARACTERIZATION OF PREDICTED SMALL PROTEINS. Allison Whited , Christina Cleveland, Jeffre Allen, Irwin Jungreis, John Rinn, Loren Hough 908-Pos Board B10 TRAVEL AWARDEE SIMULATION GUIDED DESIGN OF SPECTROSCOPY EXPERIMENTS VIA MAXIMIZING KINETIC INFORMATION GAIN. Shriyaa Mittal , Diwakar Shukla 909-Pos Board B11 STRUCTURAL BASIS UNDERLYING AUTOINDUCER ACTIVATION OF THE VIBRIO CHOLERAE VQMA QUORUM-SENSING RECEPTOR.  Jon Paczkowski 910-Pos Board B12 REINFORCEMENT LEARNING OF PROTEIN CONFORMATIONAL ENSEM- BLE.  Jiangyan Feng 911-Pos Board B13 BIOINFORMATICS OF NEW SELECTIVE INSECTICIDE TARGET IN INSECT SPECIES. Hassan M. Younis 912-Pos Board B14 DISASSEMBLING AND REASSEMBLING COMPLEX STRUCTURE OF GLUTA- MATE DEHYDROGENASE 1 (DGH-1), MONITORED BY TRYPTOPHAN AND 1-ANILINONAPHTHALENE-8-SULFONATE (ANS) FLUORIMETRY. Bogumil Zelent , David F. Wilson, Franz M. Matschinsky

.913-Pos Board B15 IN-CELL FAST PHOTOCHEMICAL OXIDATION OF PROTEINS FOR PRO- TEOME WIDE STRUCTURAL BIOLOGY. Emily E. Chea , Lisa M. Jones 914-Pos Board B16 EXPLORE THE BINDING OF HEPATITIS B VIRUS CORE PROTEIN PEPTIDES WITH HLA-A2.1 BY MOLECULAR MODELING METHODS. Lianhua Piao, Zhou Chen, Shan Chang, Jian Li, Ren Kong 915-Pos Board B17 DIVULGING CHARACTERISTIC FEATURES OF THE NOVEL Α-SYNUCLEIN OLIGOMERS AUGMENTING PARKINSON’S DISEASE. Animesh Mondal , Nakul Chandra Maiti 916-Pos Board B18 ATOMISTIC MECHANISMS UNDERLYING THE ACTIVATION OF G PROTEIN- COUPLED SWEET RECEPTOR HETERODIMER MEDIATED BY SUGAR ALCO- HOL RECOGNITION. Thanyada Rungrotmongkol 917-Pos Board B19 INVESTIGATING THE RESPONSE OF TYPE IV PILINS AND TYPE IV PILUS FILAMENTS TO APPLIED FORCE USING ALL-ATOM STEERED MOLECULAR DYNAMICS SIMULATIONS. Maria N. Fairfield , Stephen J. Jones, Nicolas Biais, Joseph L. Baker 918-Pos Board B20 PROBING THE POLYMORPHIC TRANSITION OF TYPE IV PILUS FILAMENTS UNDER FORCE USING COARSE-GRAINED MOLECULAR DYNAMICS SIMU- LATIONS. Bryan A. Bogin , Christopher A. Lovenduski, Nicolas Biais, Joseph Board B21 MOLECULAR DYNAMICS INVESTIGATIONS OF ENZYME CONFORMATION- AL CHANGES. Prabin Baral , Nisha Bhattarai, Rudramani Pokhrel, Bernard Gerstman, Prem P. Chapagain 920-Pos Board B22 HIGH YIELD PRODUCTION OF FUNCTIONAL HIF PROLYL HYDROXYLASE DOMAIN PROTEINS FROM INCLUSION BODY EXPRESSION IN E. COLI .  Nakoa K. Webber , Thomas J. Fasano, Jacob T. Zangaro, Pamela N. Gallo, Kayla A. Schardien, Michelle M. Currie, Nathaniel V. Nucci 921-Pos Board B23 STUDYING THE DYNAMIC MOTIONS OF WATER SURROUNDING THE ICE- BINDING FACE OF M1.1 ANTIFREEZE PROTEIN.  Joseph C. Iovine , Pamela N. Gallo, Kayla A. Callaway, Peter L. Davies, Nathaniel V. Nucci 922-Pos Board B24 SINGLE-MOLECULE FORCE SPECTROSCOPY OF M-VALUE MUTANTS OF STAPHYLOCOCCAL NUCLEASE INDICATES COMPLEX PROTEIN FOLDING LANDSCAPE.  James Rives , Joseph Rehfus, Vincent J. Hilser 923-Pos Board B25 COMPUTATIONAL AND SPECTROSCOPIC INVESTIGATION OF COMMUNI- CATION MECHANISMS USED BY ACYL CARRIER PROTEINS.  Terra Sztain-Pedone , Michael D. Burkart, James A. McCammon 924-Pos Board B26 DISSECTING THE ALLOSTERIC EFFECTS OF PVHL G123F MUTATION IN TYPE 2A PVHL DISEASE. Hongsheng Qian , Yu Zou, Qingwen Zhang 925-Pos Board B27 ION PAIRS BURIED IN HYDROPHOBIC ENVIRONMENTS WITHIN PROTEINS: ELECTROSTATIC CROSSTALK BETWEEN BURIED GROUPS. Aaron Robinson , Andrea Theodoru, Jamie L. Schlessman, Bertrand Garcia-Moreno 926-Pos Board B28 POLYMORPHISMS MODULATE SHEEP PRION PROTEIN SUSCEPTIBILITY TO MISFOLDING BY ALTERING THE RESIDUE NETWORK OF INTERAC- TIONS.  India Claflin , Noah Yoshida, Patricia Soto L. Baker 919-Pos

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